Do we need universal competence in space

В данной статье рассматривается вопрос влияния личностных качеств на профессиональную деятельность. К чему может привести отсутствие компетенций? Какими качествами должен обладать космонавт - испытатель? Проведен анализ трудовых функций космонавта - испытателя, и по этим данным подобраны универсальные компетенции космонавта, находящегося в космосе. Универсальные компетенции - это качества личности, от которых зависит ее успех практически во всех областях профессиональной деятельности.This article discusses the question of the impact of personal qualities on professional activities. What can be due to lack of competencies? What are the qualities of a test cosmonaut? The analysis of the job functions of test - cosmonaut on this data selected generic competence astronaut is in space. Universal jurisdiction is the quality of the person depends on its success in almost all areas of professional activity

High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid

Increased monocyte activation and intestinal damage have been shown to be predictive for the increased morbidity and mortality observed in treated people living with human immunodeficiency virus (PLHIV). A cross-sectional analysis of cellular and soluble markers of monocyte activation, coagulation, intestinal damage, and inflammation in plasma and cerebrospinal fluid (CSF) of PLHIV with suppressed plasma viremia on combination antiretroviral therapy and age and demographically comparable HIV-negative individuals participating in the Comorbidity in Relation to AIDS (COBRA) cohort and, where appropriate, age-matched blood bank donors (BBD). People living with HIV, HIV-negative individuals, and BBD had comparable percentages of classical, intermediate, and nonclassical monocytes. Expression of CD163, CD32, CD64, HLA-DR, CD38, CD40, CD86, CD91, CD11c, and CX3CR1 on monocytes did not differ between PLHIV and HIV-negative individuals, but it differed significantly from BBD. Principal component analysis revealed that 57.5% of PLHIV and 62.5% of HIV-negative individuals had a high monocyte activation profile compared with 2.9% of BBD. Cellular monocyte activation in the COBRA cohort was strongly associated with soluble markers of monocyte activation and inflammation in the CSF. People living with HIV and HIV-negative COBRA participants had high levels of cellular monocyte activation compared with age-matched BBD. High monocyte activation was predictive for inflammation in the CS