2,170 research outputs found
Depression, School Performance, and the Veridicality of Perceived Grades and Causal Attributions
An external criterion was assessed to test whether depressives have distorted perceptions of covariation information and whether their attributions are consistent with this information. Studentsâ actual and self-perceived grades, depression status, and attributions for failures were assessed. Furthermore, partici pants estimated average grades. Generally, self-perceived own past grades were inflated. Depressed students and those with low grades distorted their own grades (but not the average grade) more to their favor than individuals low in depression and those with high grades. Depression went along with lower actual grades and with internal, stable, and global failure attributions. Mood differences in attributions were not due to differences in previous grades. Depressed individuals drew (unrealistically) more depressogenic causal inferences when they perceived average grades to be low than when average grades were perceived to be high. However, they (realistically) attributed failure more in a depressogenic fashion than did nondepressives when their own grade history was low
Organizational Systems and Employee Motivation
[Excerpt] Motivation is typically thought of as a within-person phenomenon. Yet the individuals at work are a part of a larger organizational system, and as such, a more complete understanding of employee motivation recognizes the role of organizational-level factors in influencing work motivation. Major organizational practices that influence employee motivation include the evaluation, feedback, involvement, and reward systems. In addition, organizational culture and workplace policies and strategies surrounding job security, development opportunities, and diversity play a role in influencing employee motivation at work. The purpose of this chapter is to examine these organizational influences and address the impact of organizational characteristics and contemporary changes in the nature of work systems that influence employee motivation
Impact of Manure and N-Management Systems on Water Quality
Nitrate from fertilizers and manure application have been detected in the surface and ground water in many agricultural regions of the country including Iowa. The current practices of fertilizer application methods and rates are believed to be contributing significantly in the contamination of groundwater. Therefore, it is imperative that tillage and planting systems, regarded as best management practices for agricultural sustainability, minimize the potential for chemical runoff and leaching losses to groundwater with alternative chemical management systems. If the potential for contamination is not reduced by developing and successfully demonstrating the innovative nitrogen and pesticide management practices, the potential for contamination will remain and could result in additional regulations. Because of these concerns, researchers must develop alternative farming practices with the goals of reducing the input costs, and preserving the resource base for the sustainability of our agriculture and protecting the environment
On the Properties of Plastic Ablators in Laser-Driven Material Dynamics Experiments
Radiation hydrodynamics simulations were used to study the effect of plastic
ablators in laser-driven shock experiments. The sensitivity to composition and
equation of state was found to be 5-10% in ablation pressure. As was found for
metals, a laser pulse of constant irradiance gave a pressure history which
decreased by several percent per nanosecond. The pressure history could be made
more constant by adjusting the irradiance history. The impedance mismatch with
the sample gave an increase o(100%) in the pressure transmitted into the
sample, for a reduction of several tens of percent in the duration of the peak
load applied to the sample, and structured the release history by adding a
release step to a pressure close to the ablation pressure. Algebraic relations
were found between the laser pulse duration, the ablator thickness, and the
duration of the peak pressure applied to the sample, involving quantities
calculated from the equations of state of the ablator and sample using shock
dynamics.Comment: Typos fixe
Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes
The gene encoding eukaryotic initiation factor 5A (EIF5A) is found in diabetes-susceptibility loci in mouse and human. eIF5A is the only protein known to contain hypusine (hydroxyputrescine lysine), a polyamine-derived amino acid formed post-translationally in a reaction catalyzed by deoxyhypusine synthase (DHPS). Previous studies showed pharmacologic blockade of DHPS in type 1 diabetic NOD mice and type 2 diabetic db/db mice improved glucose tolerance and preserved beta cell mass, which suggests that hypusinated eIF5A (eIF5AHyp) may play a role in diabetes pathogenesis by direct action on the beta cells and/or altering the adaptive or innate immune responses. To translate these findings to human, we examined tissue from individuals with and without type 1 and type 2 diabetes to determine the expression of eIF5AHyp. We detected eIF5AHyp in beta cells, exocrine cells and immune cells; however, there was also unexpected enrichment of eIF5AHyp in pancreatic polypeptide-expressing PP cells. Interestingly, the presence of eIF5AHyp co-expressing PP cells was not enhanced with disease. These data identify new aspects of eIF5A biology and highlight the need to examine human tissue to understand disease
Operation Moshtarak and the manufacture of credible, âheroicâ warfare
Richard Lance Keeble argues that Fleet Streetâs coverage of the Afghan conflict has served largely to promote the interests of the military/industrial/media complex â and marginalise the views of the public who have consistently appealed in polls for the troops to be brought back hom
Influence of Nanoparticle Size and Shape on Oligomer Formation of an Amyloidogenic Peptide
Understanding the influence of macromolecular crowding and nanoparticles on
the formation of in-register -sheets, the primary structural component
of amyloid fibrils, is a first step towards describing \emph{in vivo} protein
aggregation and interactions between synthetic materials and proteins. Using
all atom molecular simulations in implicit solvent we illustrate the effects of
nanoparticle size, shape, and volume fraction on oligomer formation of an
amyloidogenic peptide from the transthyretin protein. Surprisingly, we find
that inert spherical crowding particles destabilize in-register -sheets
formed by dimers while stabilizing -sheets comprised of trimers and
tetramers. As the radius of the nanoparticle increases crowding effects
decrease, implying smaller crowding particles have the largest influence on the
earliest amyloid species. We explain these results using a theory based on the
depletion effect. Finally, we show that spherocylindrical crowders destabilize
the ordered -sheet dimer to a greater extent than spherical crowders,
which underscores the influence of nanoparticle shape on protein aggregation
Mechanically Stabilized Tetrathiafulvalene Radical Dimers
Two donorâacceptor [3]catenanesâcomposed of a tetracationic molecular square, cyclobis(paraquat-4,4âČ-biphenylene), as the Ï-electron deficient ring and either two tetrathiafulvalene (TTF) and 1,5-dioxynaphthalene (DNP) containing macrocycles or two TTF-butadiyne-containing macrocycles as the Ï-electron rich componentsâhave been investigated in order to study their ability to form TTF radical dimers. It has been proven that the mechanically interlocked nature of the [3]catenanes facilitates the formation of the TTF radical dimers under redox control, allowing an investigation to be performed on these intermolecular interactions in a so-called âmolecular flaskâ under ambient conditions in considerable detail. In addition, it has also been shown that the stability of the TTF radical-cation dimers can be tuned by varying the secondary binding motifs in the [3]catenanes. By replacing the DNP station with a butadiyne group, the distribution of the TTF radical-cation dimer can be changed from 60% to 100%. These findings have been established by several techniques including cyclic voltammetry, spectroelectrochemistry and UVâvisâNIR and EPR spectroscopies, as well as with X-ray diffraction analysis which has provided a range of solid-state crystal structures. The experimental data are also supported by high-level DFT calculations. The results contribute significantly to our fundamental understanding of the interactions within the TTF radical dimers
Reviews
Miscellany. . Reviewed by George Colvin.
Wilkie Collins: A Critical and Biographical Study. Dorothy L. Sayers, ed. E.R. Gregory. Reviewed by J. R. Christopher.
Bloodhounds of Heaven: The Detective in English Fiction from Godwin to Doyle. Ian Ousby. Reviewed by J. R. Christopher.
The Dark Tower and Other Stories. C.S. Lewis, Ed. Walter Hooper. Reviewed by Nancy-Lou Patterson.
The Mythology of Middle-earth. Ruth S. Noel. Reviewed by Nancy-Lou Patterson.
Faeries. Brian Froud and Alan Lee. Reviewed by Robert S. Ellwood Jr..
Eschatus. Bruce Pennington. Reviewed by Robert S. Ellwood Jr..
The Lord of the Rings. Ralph Bakshi, director; Saul Zaentz, producer. Reviewed by Steven C. Walker.
The Lord of the Rings. Ralph Bakshi, director; Saul Zaentz, producer. Reviewed by Dale Ziegler
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