Factors that Affect Maternal Care Seeking Behaviour and the Choice of Practitioner(s) during Complications: the Case of Mang’anja Tribe in Malawi

Despite the high prevalence rate of maternal mortality coupled with under-utilisation of health services, little attempt has been made in Malawi to explore and document people’s understanding and beliefs about causes and appropriate treatment of the major complications that are medically believed to be the causes of maternal deaths. Any difference between the insider’s and the biomedical perceptions of what is a serious maternal complication is dangerous because it may delay seeking of lifesaving care. This study was therefore, designed to elicit and explore the local explanatory associated with the major biomedical cause of maternal mortality (haemorrhage) among Mang’anja tribe in Malawi and how these influence care seeking behaviour. Descriptive qualitative research design was adopted and data was collected using Kleinman’s ‘explanatory model interview guide’ from 25 respondents. The findings generally suggest that being aware of maternal danger signs is not enough to provoke a trip to the appropriate healer. Since it is the cause not the effect of the maternal complications that determines care seeking, a shift in approach of health education provided to pregnant women is recommended. Keywords: Malawi, maternal health, explanatory model, care seeking, haemorrhag

A Multimethod Examination of the Motives and Effects of Herbal Medicine Use During Pregnancy

Background There are suggestions that the use of herbal medicine during pregnancy is associated with adverse pregnancy outcomes. However, the extent of use, the reasons for use and the link between use and poor outcomes have not been rigorously studied. So, my PhD research examined associations between the use of herbal medicine during pregnancy and adverse maternal and neonatal outcomes. It also explored the socio-cultural explanations of the pregnancy-related problems and how this influences the use of herbal medicine. Methods The PhD research project comprised of four sub-studies. The first was a systematic review and meta-analysis of the effectiveness, safety and prevalence of herbal medicines during pregnancy at global and regional (sub-Saharan Africa) levels. The second was a secondary analysis of Cluster-randomised controlled trial data from Malawi. For this analysis, I examined the link between herbal medicine use and adverse pregnancy outcomes amongst 32,254 births recorded from 2005 to 2010 in Mchinji. The other two sub-studies were part of a field-based ‘exploratory sequential mixed-methods study’ in Malawi. I first conducted a qualitative study involving semi-structured interviews with women who had recently (<24 months) given birth (n=10) and focus group discussions with grandmothers or traditional birth attendants (n=2) and community health workers (n=2). This was followed by a hospital-based case-cohort study with 1,830 women (15-49 years old) who had just given birth. The motives for herbal medicine use and the associations between herbal medicine use and pregnancy outcomes were assessed. Results Multiple explanations of pregnancy complications were identified, and most of them are grounded in cultural beliefs. Specifically, most pregnancy problems were attributed to witchcraft and associated supernatural forces. The findings further show that the explanations of pregnancy problems influence the choice of practitioners and care-seeking practices, including the use of herbal medicine. Herbal medicine use during pregnancy is high in both Malawi and other sub-Saharan countries. I also found that some of the herbal medicines were associated with adverse maternal and neonatal outcomes (e.g. pre-labour rupture of membranes and neonatal death) while others were not. Conclusion There appear to be mixed-effects of herbal medicines during pregnancy. Some were associated with adverse pregnancy outcomes whereas others were not. Because it is not yet clear as to which herbal medicines are safe or not, the key recommendation from this thesis is that where possible all herbal medicines of unproven safety should be avoided during pregnancy

Associations between the use of herbal medicines and adverse pregnancy outcomes in rural Malawi : a secondary analysis of randomised controlled trial data

BACKGROUND: The use of herbal medicines during pregnancy is very high globally and previous studies have pointed out possible associations with adverse pregnancy outcomes. Nevertheless, the safety of herbal medicines in pregnancy is under-explored in low-income countries experiencing high maternal and neonatal complications. We investigated the associations between self-reported use of Mwanamphepo (a group of herbal medicines commonly used to induce or hasten labour) and adverse maternal and neonatal outcomes in rural Malawi. METHODS: We conducted a cross-sectional analysis of secondary household data relating to 8219 births that occurred between 2005 and 2010 in Mchinji district, Malawi. The data were collected as part of a cluster-randomised controlled trial (RCT) that evaluated community interventions designed to reduce maternal and neonatal mortality. Data were gathered on maternity history, demographic characteristics, pregnancy outcomes and exposure to Mwanamphepo. Associations between self-reported use of Mwanamphepo and maternal morbidity as well as neonatal death or morbidity were examined using mixed-effects models, adjusted for relevant covariates. All analyses were also adjusted for the clustered nature of the survey. RESULTS: Of the 8219 births, Mwanamphepo was used in 2113 pregnancies, representing an estimated prevalence of 25.7%. The self-reported use of Mwanamphepo was significantly associated with increased occurrence of maternal morbidity and neonatal death or morbidity. Specifically, the odds of maternal morbidity were 28% higher among self-reported users than non-users of Mwanamphepo (AOR = 1.28; 95% CI = 1.09-1.50) and the probabilities of neonatal death or morbidity were 22% higher (AOR =1.22; 95% CI = 1.06-1.40) among neonates whose mother reportedly used Mwanamphepo than those who did not. CONCLUSION: The use of Mwanamphepo was associated with adverse pregnancy outcomes in rural Malawi. Thus, herbal medicines may not be safe in pregnancy. Where possible, pregnant women should be discouraged from using herbal medicines of unconfirmed safety and those who report to have used should be closely monitored by health professionals. The study was limited by the self-report of exposure and unavailability of data relating to some possible confounders

Effectiveness and safety of herbal medicines for induction of labour : a systematic review and meta-analysis

OBJECTIVE: The use of herbal medicines for induction of labour (IOL) is common globally and yet its effects are not well understood. We assessed the efficacy and safety of herbal medicines for IOL. DESIGN: Systematic review and meta-analysis of published literature. DATA SOURCES: We searched in MEDLINE, AMED and CINAHL in April 2017, updated in June 2018. ELIGIBILITY CRITERIA: We considered experimental and non-experimental studies that compared relevant pregnancy outcomes between users and non-user of herbal medicines for IOL. DATA EXTRACTION AND SYNTHESIS: Data were extracted by two reviewers using a standardised form. A random-effects model was used to synthesise effects sizes and heterogeneity was explored through I2 statistic. The risk of bias was assessed using 'John Hopkins Nursing School Critical Appraisal Tool' and 'Cochrane Risk of Bias Tool'. RESULTS: A total of 1421 papers were identified through the searches, but only 10 were retained after eligibility and risk of bias assessments. The users of herbal medicine for IOL were significantly more likely to give birth within 24 hours than non-users (Risk Ratio (RR) 4.48; 95% CI 1.75 to 11.44). No significant difference in the incidence of caesarean section (RR 1.19; 95% CI 0.76 to 1.86), assisted vaginal delivery (RR 0.73; 95% CI 0.47 to 1.14), haemorrhage (RR 0.84; 95% CI 0.44 to 1.60), meconium-stained liquor (RR 1.20; 95% CI 0.65 to 2.23) and admission to nursery (RR 1.08; 95% CI 0.49 to 2.38) was found between users and non-users of herbal medicines for IOL. CONCLUSIONS: The findings suggest that herbal medicines for IOL are effective, but there is inconclusive evidence of safety due to lack of good quality data. Thus, the use of herbal medicines for IOL should be avoided until safety issues are clarified. More studies are recommended to establish the safety of herbal medicines

Reaching the poor with health interventions: Programme-incidence analysis of seven randomised trials of women's groups to reduce newborn mortality in Asia and Africa

Background Efforts to end preventable newborn deaths will fail if the poor are not reached with effective interventions. To understand what works to reach vulnerable groups, we describe and explain the uptake of a highly effective community-based newborn health intervention across social strata in Asia and Africa. Methods We conducted a secondary analysis of seven randomised trials of participatory women's groups to reduce newborn mortality in India, Bangladesh, Nepal and Malawi. We analysed data on 70 574 pregnancies. Socioeconomic and sociodemographic differences in group attendance were tested using logistic regression. Qualitative data were collected at each trial site (225 focus groups, 20 interviews) to understand our results. Results Socioeconomic differences in women's group attendance were small, except for occasional lower attendance by elites. Sociodemographic differences were large, with lower attendance by young primigravid women in African as well as in South Asian sites. The intervention was considered relevant and interesting to all socioeconomic groups. Local facilitators ensured inclusion of poorer women. Embarrassment and family constraints on movement outside the home restricted attendance among primigravid women. Reproductive health discussions were perceived as inappropriate for them. Conclusions Community-based women's groups can help to reach every newborn with effective interventions. Equitable intervention uptake is enhanced when facilitators actively encourage all women to attend, organise meetings at the participants' convenience and use approaches that are easily understandable for the less educated. Focused efforts to include primigravid women are necessary, working with families and communities to decrease social taboos

Documentation of the partograph in assessing the progress of labour by health care providers in Malawi’s South-West zone

Abstract Background There is some evidence that appropriate use of partograph in monitoring the progress of labour could decrease delivery related complications. The documentation of parameters of partographs is however, poorly understood. The aim of the present study was to determine the extent to which health care workers are making use of the partograph in monitoring the progress of labour through checking the documentation of the parameters of the partographs. Methods A hospital-based descriptive study involving retrospective review of partographs for births that occurred in 2016 was conducted in Malawi’s South-West zone. A total of 1070 partographs that were used to monitor labour in two public hospitals were reviewed to determine the documentation of the parameters of partographs and descriptive statistics were computed using statistical package for the social science software version 22.0. Results Of the total 1070 partographs reviewed, 58.6% (n = 627) of the partographs had no recording of maternal blood pressure and 65.3% (n = 699) of the partographs had no temperature documentation. Moulding was not recorded in 25.4% (n = 272) of the partographs, foetal heart rate was not recorded in 14.9% (n = 159) of the partographs and descent of the foetal head was not recorded in 12.0% (n = 128) of the partographs. Conclusion There is poor documentation of vital parameters of the partographs. This suggests insufficient monitoring of the progress of labour, which may lead to adverse pregnancy outcomes. To improve the accurate documentation of parameters of the partograph, there is a need to understand the problem and provide tailor-made solutions to address them and ultimately improve pregnancy outcomes. In the meantime, in-service refresher courses on partograph use to health care workers need to be conducted regularly. Supportive supervision to obstetric care providers and regular partograph audit could also improve documentation

Understanding the mechanisms through which women's group community participatory intervention improved maternal health outcomes in rural Malawi: was the use of contraceptives the pathway?

Background: Women's group intervention is a community based initiative through which rural women form groups, meet regularly to discuss maternal health issues affecting them, and come up with locally available solutions. This intervention has been associated with reduced maternal and neonatal mortality in limited resource settings. Nevertheless, the mechanisms through which women's groups influence maternal health outcomes are uncertain. Because contraception reduces the risk of maternal mortality and women's groups also tackled this issue, we speculated that contraceptive use might be the pathway. Consequently, this study investigated whether participation in women's groups was associated with contraceptive use in Malawi. Design: We examined the use of contraceptives between women who participated in women's groups and those who did not through a community-based cross-sectional study in Mchinji, Malawi. The study involved 3,435 women of reproductive age (15–49 years) who were recruited using a multistage sampling approach. Members (treated) and non-members (control) of women's groups were matched on observed covariates using propensity scores and the counterfactual for the treated individuals was estimated. Results: Crude analysis revealed that women's groups improved uptake of contraceptives by 26% (odds ratio (OR)=1.26; 95% confidence interval (CI)=1.03–1.56; p=0.024). However, using the matched data, uptake of contraceptives was almost the same among members and non-members of women's groups. More precisely, the likelihood of using contraceptives was not significantly different between the members and non-members of women's groups (OR=1.00; 95% CI=0.81–1.24; p=0.991). Conclusions: There is insufficient evidence of an association between participation in women's groups and contraceptive use among rural Malawian women. The implication is that contraception was not the mechanism through which women's groups contributed to reduced maternal mortality in Malawi. Because the effects of community interventions are usually comprehensive and sometimes difficult to demonstrate, ethnographic studies should be considered in the evaluation of women's groups and other related interventions

Factors associated with contraceptive use among young women in Malawi: analysis of the 2015–16 Malawi demographic and health survey data

Abstract Background Although Malawi is one of the countries with highest Contraceptive Prevalence Rate (CPR) in Sub–Saharan Africa, pregnancies and fertility among young women remain high. This suggests low up take of contraceptives by young women. The aim of this study was to investigate the factors associated with contraceptive use among young women in Malawi. Methods This is a secondary analysis of household data for 10,422 young women aged 15–24 years collected during the 2015–16 Malawi Demographic and Health Survey (MDHS). The sample was weighted to ensure representativeness. Descriptive statistics, bivariate and multivariate logistic regressions were performed to assess the demographic, social – economic and other factors that influence contraceptive use among young women. Crude Odds Ratio (COR) and Adjusted Odds Ratio (AOR) with their corresponding 95% confidence intervals (95% CI) were computed using the Statistical Package for the Social Sciences version 22.0. Results Of the 10,422 young women, 3219 used contraception representing a prevalence of 30.9%. The findings indicate that age, region of residence, marital status, education, religion, work status, a visit to health facility, and knowledge of the ovulatory cycle are significant predictors of contraceptive use among young women in Malawi. Women who were in the age group 20–24 years (AOR = 1.93; 95% CI = 1.73–2.16), working (AOR = 1.26; 95% CI = 1.14–1.39), currently married (AOR = 6.26; 95% CI = 5.46–7.18), knowledgeable about their ovulatory cycle (AOR = 1.75; 95% CI = 1.50–2.05), and those with primary education (AOR = 1.47; 95% CI = 1.18–1.83) were more likely to use contraceptives than their counterparts. Conclusion This study has demonstrated that several social demographic and economic factors are associated with contraceptive use among young women in Malawi. These findings should be considered and reflected in public health policies to address issues that could be barriers to the use of contraception by young women. Strengthening access to family planning information and services for young women is highly recommended to reduce pregnancies among young women in Malawi