Sleep apnea in patients with primary chronic headache

Introduction. Sleep apnea syndrome (SAS) can accompany patients with chronic primary headache (CPH), being a frequent cause of persistence of symptoms in these patients, however, the data studying this disorder in patients with CPH are still limited. Objective. To determine the frequency of SAS in patients with CPH. Methods. A retrospective cohort was analyzed in patients with a diagnosis of CPH in a third level hospital. CPH was diagnosed according to the criteria of the International Headache Society and SAS with a polysomnographic record with an apnea-hypopnea index (AHI) >5/h, the frequency of SAS was determined among the total number of patients with AHI >5/h over the total number of patients undergoing polysomnography. Results. A total of 114 subjects were included, where the SAS in CPH was 83.3%, of which 56.8% were men and 60% older than 50 years; 89% of the population had a body mass index (BMI) greater than 27 kg/m2. Fatigue and sleepiness during the day were the most frequent symptoms, reported in 89.5% of the population with SAS compared to 47.4% of the population without a diagnosis of SAS. Conclusion. Sleep apnea is a frequent condition in patients with CPH undergoing polysomnography, mainly overweight men over 50 years of age. The main associated symptoms are fatigue and sleepiness

Trastorno de estrés postraumático post COVID-19: una revisión exploratoria

Introducción: El trastorno de estrés postraumático (TEPT) se presenta en individuos expuestos a situaciones traumáticas o amenazantes. La pandemia por la COVID-19 ha traído consigo repercusiones tanto físicas como mentales para las personas. Objetivo: Explorar la evidencia médica actual sobre el TEPT pos COVID-19

Eficacia y seguridad del bloqueo del plano anterior del serrato y pectoral en cirugía torácica: una revisión exploratoria

Introducción: Las técnicas analgésicas locorregionales son consideradas parte fundamental en los protocolos de analgesia multimodal. El bloqueo del plano anterior del serrato y plano pectoral son nuevas técnicas de anestesia regional establecidas en la toracotomía, fractura costal e incluso en las cirugías torácicas mínimamente invasivas

CRISPR and gene editing in HIV therapy: A scoping review

Human immunodeficiency virus (HIV) is nowadays one of the major health problems worldwide. Several strategies have been explored for the eradication of latent HIV-1 reservoirs, current antiretroviral therapy stops the progression of HIV disease, however, as new therapies are being developed, CRISPR (clustered regularly interspaced short palindromic repeats) systems have recently been used as a genome editing technique. CRISPR is becoming progressively one of the possible cures, although it remains experimental, for HIV in medical research. This systematic review summarizes literature evidence of CRISPR gene editing in HIV/AIDS therapy. This study also identifies the research gaps in the current literature, helping to guide future research

Dispositivos de retroalimentación en tiempo real para evaluar la calidad de las compresiones torácicas en maniquíes de práctica: una revisión sistemática exploratoria

La Reanimación Cardiopulmonar es un procedimiento de emergencia realizado a pacientes con parada cardiaca. En la actualidad la evaluación or medio de dispositivos de retroalimentación en tiempo real para evaluar la calidad de reanimación cardiopulmonar en personal experto y no experto es indispensable para impactar favorablemente en la efectividad de estas, al permitir correcciones inmediatas de la técnica empleada durante la reanimación. El objetivo de esta revisión sistemática exploratoria es determinar qué dispositivos existen actualmente para evaluar la calidad de las compresiones torácicas en maniquíes de práctica y su efectividad para lograr compresiones efectivas durante la reanimación cardiopulmonar por medio de un mapeo de la literatura disponible en las bases PUBMED, EMBASE, Web of Science y Mednar