46 research outputs found

    G Matrix for Tetrahedral X4 Y 4 Molecules

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    Since the development of \u27 the so called G F matrix method1 force constants; calculations for many molecules of different structure have be.en performed. It is not difficult to obtain the elements of the G matrix for a molecule directly from s vectors, or from the general tables of g matrix elements?. However, the final G ;k elemoots are Teipo,rted ror most moleCUilar stvuctures. To complete ithe materlial we fist the Gik for tetrahedral X 4 Y 4 , one -0f a few simplestructuir. es .so far not !being discU!Ssed. Thi:s S;tructure is reahzed, e.g. in boron tetrachloride

    A monoclonal antibody to the rat Crry/p65 antigen, a complement regulatory membrane protein, stimulates adhesion and proliferation of thymocytes

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    A murine monoclonal antibody (mAb), 3F10, was produced by fusion of spleen cells obtained from mice immunized with a rat cortical thymic epithelial cell line (R-TNC.1) stimulated with interferon-gamma and P3X myeloma cells. 3F10 recognized an antigen expressed both on thymocytes and non-lymphoid cells in the thymus. Flow cytometry showed that 3F10 stained more than 98% thymocytes and 90% R-TNC.1 cells. Immunoprecipitation and Western blot studies demonstrated that 3F10 reacted with molecules of 55000 and 65000 MW from both thymocyte and R-TNC.1 cell lysates. 3F10 recognized the same antigen on Chinese hamster ovary cells transfected with rat Crry as did 5I2 mAb, confirming the specificity of 3F10 mAb for the rat homologue of mouse Crry/p65, a membrane-bound complement regulatory protein. 3F10 mAb induced homotypic aggregation of thymocytes and exhibited an additive effect on the aggregation evoked by phorbol myristate acetate. The aggregation was dependent on active cell metabolism, intact cytoskeleton, divalent cations and activation of protein phosphatases 1 and 2A (as assessed by use of okadaic acid). In contrast, H-7, HA1004 and genistein partially inhibited, whereas staurosporine potentiated the aggregation of thymocytes triggered by 3F10. 3F10 mAb also stimulated binding of thymocytes to the R-TNC.1 line. Both homotypic and heterotypic adhesive interactions are mediated by leucocyte function-associated antigen-1 (LFA-1). In addition, 3F10 stimulated proliferation of thymocytes induced by suboptimal concentrations of concanavalin A. These data suggest that rat Crry/p65 might be involved in the regulation of both cell adhesion and activation of thymocytes. This is a novel, non-complement-dependent function of Crry/p65

    Properties of the Strange Axial Mesons in the Relativized Quark Model

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    We studied properties of the strange axial mesons in the relativized quark model. We calculated the K1K_1 decay constant in the quark model and showed how it can be used to extract the K1(3P1)K1(1P1)K_1 (^3P_1) - K_1 (^1P_1) mixing angle (θK\theta_K) from the weak decay τK1ντ\tau \to K_1 \nu_\tau. The ratio BR(τντK1(1270))/BR(τντK1(1400))BR(\tau \to \nu_\tau K_1 (1270))/BR(\tau\to \nu_\tau K_1(1400)) is the most sensitive measurement and also the most reliable since the largest of the theoretical uncertainties factor out. However the current bounds extracted from the TPC/Two-Gamma collaboration measurements are rather weak: we typically obtain 30oθK50o-30^o \lesssim \theta_K \lesssim 50^o at 68\% C.L. We also calculated the strong OZI-allowed decays in the pseudoscalar emission model and the flux-tube breaking model and extracted a 3P11P1^3P_1 - ^1P_1 mixing angle of θK45o\theta_K \simeq 45^o. Our analysis also indicates that the heavy quark limit does not give a good description of the strange mesons.Comment: Revised version to be published in Phys. Rev. D. Minor changes. Latex file uses revtex version 3 and epsfig, 4 postcript figures are attached. The full postcript version with embedded figures is available at ftp://ftp.physics.carleton.ca/pub/theory/godfrey/ocipc9512.ps.

    Host response mechanisms in periodontal diseases

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    Stereological analysis of the thymic epithelial cells in rats during ontogenesis

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