3,053 research outputs found
Counsel Fees in Stockholders\u27 Derivative and Class Actions-Hornstein Revisited
In 1939, the first in a series of four comprehensive law review articles by Professor George D. Hornstein was published on the subject of the award of counsel fees in stockholders\u27 derivative suits and corporate class actions. These articles highlighted equitable principles peculiar to such actions, previously not fully understood by either attorneys or the courts, which have made derivative and class actions extremely effective weapons in the battle for corporate democracy. Three very basic questions were posed and answered: 1) Who will pay for the attorneys fees and expenses incurred in such litigation? 2) What factors govern the award of counsel fees? 3) How are they calculated
Ejection of Supernova-Enriched Gas From Dwarf Disk Galaxies
We examine the efficiency with which supernova-enriched gas may be ejected
from dwarf disk galaxies, using a methodology previously employed to study the
self-enrichment efficiency of dwarf spheroidal systems. Unlike previous studies
that focused on highly concentrated starbursts, in the current work we consider
discrete supernova events spread throughout various fractions of the disk. We
model disk systems having gas masses of 10^8 and 10^9 solar masses with
supernova rates of 30, 300, and 3000 per Myr. The supernova events are confined
to the midplane of the disk, but distributed over radii of 0, 30, and 80% of
the disk radius, consistent with expectations for Type II supernovae. In
agreement with earlier studies, we find that the enriched material from
supernovae is largely lost when the supernovae are concentrated near the
nucleus, as expected for a starburst event. In contrast, however, we find the
loss of enriched material to be much less efficient when the supernovae occur
over even a relatively small fraction of the disk. The difference is due to the
ability of the system to relax following supernova events that occur over more
extended regions. Larger physical separations also reduce the likelihood of
supernovae going off within low-density "chimneys" swept out by previous
supernovae. We also find that, for the most distributed systems, significant
metal loss is more likely to be accompanied by significant mass loss. A
comparison with theoretical predications indicates that, when undergoing
self-regulated star formation, galaxies in the mass range considered shall
efficiently retain the products of Type II supernovae.Comment: 16 pages, 14 figures, to appear in Astrophysical Journal; higher
resolution figures available through Ap
Immunolocalization of the Heterotrimeric Kinesin-Related Protein KRP(85/95) in the Mitotic Apparatus of Sea Urchin Embryos
AbstractWe have used monoclonal antibodies to perform confocal light microscopic immunolocalization of KRP(85/95), a heterotrimeric plus-end-directed microtubule motor protein, in dividing cells of sea urchin embryos. Embryos were stained during the first division cycle, and dissociated blastomeres were stained at the 32- to 64-cell stages. Double labeling of the dividing cells with anti-tubulin and anti-KRP(85/95) showed a clear concentration of the motor protein in the mitotic apparatus; KRP(85/95) appeared to associate with pericentriolar regions during prophase, with kinetochore-to-pole microtubules during metaphase, and, in a striking fashion, with the spindle interzone during anaphase. KRP(85/95) began to accumulate in the interzone immediately following chromosome separation and the area of concentration expanded with the lengthening of the interzonal region during anaphase. During telophase KRP(85/95) appeared to disperse with the establishment of the cleavage furrow and did not concentrate in the midbody. KRP(85/95) staining in the mitotic apparatus was punctate and detergent-sensitive, suggesting an association with membranous vesicles, but unlike kinesin, KRP(85/95) did not appear to codistribute with calsequestrin-containing endoplasmic reticulum. Finally, KRP(85/95) appears to be present in dividing blastomeres up to at least the blastula stage, but, unlike kinesin, it is not expressed in terminally differentiated, nonmitotic coelomocytes of the adult animal. These results suggest that the expression and targeting of KRP(85/95) and kinesin differ and that KRP(85/95) may play a role in vesicle transport during embryonic cell division
Roche Lobe Overflow from Dwarf Stellar Systems
We use both analytical analyses and numerical simulations to examine the
evolution of residual gas within tidally-limited dwarf galaxies and globular
clusters. If the gas sound speed exceeds about 10% of the central velocity
dispersion, as is the case for ionized gas within small stellar systems, the
gas shall have significant density at the tidal radius, and the gas may be lost
on timescales as short as a few times the sound crossing time of the system. In
colder systems, the density at the tidal radius is much lower, greatly reducing
the mass loss rate, and the system may retain its gas for a Hubble time. The
tidally removed gas shall follow an orbit close to that of the original host
system, forming an extended stream of ionized, gaseous debris. Tidal mass loss
severely limits the ability of dwarf systems to continuously form stars. The
ordinary gas content in many dwarf galaxies is fully ionized during high
red-shift epochs, possibly preventing star formation in some systems, leading
to the formation of starless, dark-matter concentrations. In either the field
or in the center of galaxy clusters, ionized gas may be retained by dwarf
galaxies, even though its sound speed may be comparable to or even exceed the
velocity dispersion. These processes may help to explain some observed
differences among dwarf galaxy types, as well as observations of the haloes of
massive galaxies.Comment: 28 pages, LaTeX, AASTex macro
The Local Effects of Cosmological Variations in Physical 'Constants' and Scalar Fields I. Spherically Symmetric Spacetimes
We apply the method of matched asymptotic expansions to analyse whether
cosmological variations in physical `constants' and scalar fields are
detectable, locally, on the surface of local gravitationally bound systems such
as planets and stars, or inside virialised systems like galaxies and clusters.
We assume spherical symmetry and derive a sufficient condition for the local
time variation of the scalar fields that drive varying constants to track the
cosmological one. We calculate a number of specific examples in detail by
matching the Schwarzschild spacetime to spherically symmetric inhomogeneous
Tolman-Bondi metrics in an intermediate region by rigorously construction
matched asymptotic expansions on cosmological and local astronomical scales
which overlap in an intermediate domain. We conclude that, independent of the
details of the scalar-field theory describing the varying `constant', the
condition for cosmological variations to be measured locally is almost always
satisfied in physically realistic situations. The proof of this statement
provides a rigorous justification for using terrestrial experiments and solar
system observations to constrain or detect any cosmological time variations in
the traditional `constants' of Nature.Comment: 30 pages, 3 figures; corrected typo
Supernova Enrichment of Dwarf Spheroidal Galaxies
(Abridged) Many dwarf galaxies exhibit sub-Solar metallicities, with some
star-to-star variation, despite often containing multiple generations of stars.
The total metal content in these systems is much less than expected from the
heavy element production of massive stars in each episode of star formation.
Such a deficiency implies that a substantial fraction of the enriched material
has been lost from these small galaxies. Mass ejection from dwarf galaxies may
have important consequences for the evolution of the intergalactic medium and
for the evolution of massive galaxies, which themselves may have formed via the
merger of smaller systems. We report here the results of three-dimensional
simulations of the evolution of supernova-enriched gas within dwarf spheroidal
galaxies (dSph's), with the aim of determining the retention efficiency of
supernova ejecta. We consider two galaxy models, selected to represent opposite
ends of the dSph sequence. For each model galaxy we investigate a number of
scenarios, ranging from a single supernova in smooth gas distributions to more
complex multiple supernovae in highly disturbed gas distributions. The results
of these investigations suggest that, for low star-formation efficiencies, it
is difficult to completely expel the enriched material from the galaxy. Most of
the enriched gas is, however, lost from the core of the galaxy following
multiple supernovae, especially if the interstellar medium is already highly
disturbed by processes such as photo-ionization and stellar winds. If
subsequent star formation occurs predominantly within the core where most of
the residual gas is concentrated, then these results could explain the poor
self-enrichment efficiency observed in dwarf galaxies.Comment: 29 pages, 10 figures, to appear in Astrophysical Journa
The DEEP2 Galaxy Redshift Survey: Spectral classification of galaxies at z~1
We present a Principal Component Analysis (PCA)-based spectral
classification, eta, for the first 5600 galaxies observed in the DEEP2 Redshift
Survey. This parameter provides a very pronounced separation between absorption
and emission dominated galaxy spectra - corresponding to passively evolving and
actively star-forming galaxies in the survey respectively. In addition it is
shown that despite the high resolution of the observed spectra, this parameter
alone can be used to quite accurately reconstruct any given galaxy spectrum,
suggesting there are not many `degrees of freedom' in the observed spectra of
this galaxy population. It is argued that this form of classification, eta,
will be particularly valuable in making future comparisons between high and
low-redshift galaxy surveys for which very large spectroscopic samples are now
readily available, particularly when used in conjunction with high-resolution
spectral synthesis models which will be made public in the near future. We also
discuss the relative advantages of this approach to distant galaxy
classification compared to other methods such as colors and morphologies.
Finally, we compare the classification derived here with that adopted for the
2dF Galaxy Redshift Survey and in so doing show that the two systems are very
similar. This will be particularly useful in subsequent analyses when making
comparisons between results from each of these surveys to study evolution in
the galaxy populations and large-scale structure.Comment: 10 pages, 9 figures, Accepted for publication in Ap
Safety Evaluation of EXPAREL (DepoFoam Bupivacaine) Administered by Repeated Subcutaneous Injection in Rabbits and Dogs: Species Comparison
EXPAREL (bupivacaine extended-release liposome injection), DepoFoam bupivacaine, is in development for prolonged postsurgical analgesia. Repeat-dose toxicity studies were conducted in rabbits and dogs to compare the potential local and systemic toxicities of EXPAREL and bupivacaine HCl (Bsol), and the reversibility of any effects. Dogs tolerated much larger doses than rabbits. EXPAREL-related minimal-to-moderate granulomatous inflammation was noted at the injection sites. In recovery animals, the granulomatous inflammation was observed less frequently and was characterized by an increased number of multinucleated giant cells. These effects were considered a normal response to liposomes and nonadverse. Rabbits are more sensitive than dogs. In rabbits, convulsions were noted with EXPAREL and more frequently with Bsol; a NOAEL was not identified. In dogs, EXPAREL was well tolerated (NOAEL > 30 mg/kg/dose). The cumulative exposure of EXPAREL in these studies is well in excess of the proposed maximum single-dose exposure that is intended in humans
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