X-ray powder diffraction of high-absorption materials at the XRD1 beamline off the best conditions: Application to (Gd,Nd)5Si4 compounds

Representative compounds of the new family of magnetic materials Gd5-xNdxSi4 were analyzed by X-ray diffraction at the XRD1 beamline at LNLS. To reduce X-ray absorption, thin layers of the powder samples were mounted outside the capillaries and measured in Debye-Scherrer geometry as usual. The X-ray diffraction analyses and the magnetometry results indicate that the behavior of the magnetic transition temperature as a function of Nd content may be directly related to the average of the four smallest interatomic distances between different rare earth sites of the majority phase of each compound. The quality and consistency of the results show that the XRD1 beamline is able to perform satisfactory X-ray diffraction experiments on high-absorption materials even off the best conditions.Comment: 12 pages, 3 figures, 3 table

Investigation of the existence of hybrid stars using Nambu-Jona-Lasinio models

We investigate the hadron-quark phase transition inside neutron stars and obtain mass-radius relations for hybrid stars. The equation of state for the quark phase using the standard NJL model is too soft leading to an unstable star and suggesting a modification of the NJL model by introducing a momentum cutoff dependent on the chemical potential. However, even in this approach, the instability remains. In order to remedy the instability we suggest the introduction of a vector coupling in the NJL model, which makes the EoS stiffer, reducing the instability. We conclude that the possible existence of quark matter inside the stars require high densities, leading to very compact stars.Comment: 4 pages, 2 figures; prepared for IV International Workshop on Astronomy and Relativistic Astrophysics (IWARA 2009), Maresias, 4-8 Oct 200

Avaliação econômica dos métodos de irrigação por gotejo e por sulco na cultura do melão.

Realizou-se uma análise econômica de um trabalho de comparação de métodos de irrigação realizado no período de agosto a novembro de 1977 no Campo Experimental de Bebedouro, pertencente ao Centro de Pesquisa Agropecuária do Trópico Semi-Árido (EMBRAPA), Petrolina, PE. Foram apropriados os custos e benefícios dos métodos de irrigação por sulcos e gotejo em diversas condições de manejo na cultura do melão, variedade Valenciano Amarelo.bitstream/item/133206/1/32103-1.pd

An intact signal peptide on dengue virus E protein enhances immunogenicity for CD8+ T cells and antibody when expressed from modified vaccinia Ankara

Dengue is a global public health concern and this is aggravated by a lack of vaccines or antiviral therapies. Despite the well-known role of CD8(+) T cells in the immunopathogenesis of Dengue virus (DENV), only recent studies have highlighted the importance of this arm of the immune response in protection against the disease. Thus, the majority of DENV vaccine candidates are designed to achieve protective titers of neutralizing antibodies, with less regard for cellular responses. Here, we used a mouse model to investigate CD8(+) T cell and humoral responses to a set of potential DENV vaccines based on recombinant modified vaccinia virus Ankara (rMVA). To enable this study, we identified two CD8(+) T cell epitopes in the DENV-3 E protein in C57BL/6 mice. Using these we found that all the rMVA vaccines elicited DENV-specific CD8(+) T cells that were cytotoxic in vivo and polyfunctional in vitro. Moreover, vaccines expressing the E protein with an intact signal peptide sequence elicited more DENV-specific CD8(+) T cells than those expressing E proteins in the cytoplasm. Significantly, it was these same ER-targeted E protein vaccines that elicited antibody responses. Our results support the further development of rMVA vaccines expressing DENV E proteins and add to the tools available for dengue vaccine development.Parts of this work were supported by the InstitutoNacional de Ciência e Tecnologia de Vacinas–INCTV (National Insti-tute of Science and Technology of Vaccines) and by a FAPEMIGPPM grant (CBB, PPM-00461-11). BRQ was a CAPES/PDSE fellow-ship recipient (8815-11-9). FGF is a CNPq fellowship recipient. DCTis an ARC Future Fellow (FT110100310)