866 research outputs found

    Are We Missing an Opportunity? Prediabetes in the U.S. Military

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    INTRODUCTION: The prevalence of prediabetes is estimated to be one-third of Americans with approximately 80% of these individuals unaware of the diagnosis. In the active duty military population, the prevalence of prediabetes is largely unexplored. The purpose of this study was to investigate the prevalence of prediabetes in military service members by quantifying those meeting prediabetes screening criteria, those actually being screened, and those being appropriately diagnosed. MATERIALS AND METHODS: Data were analyzed from calendar years 2014 to 2018 for active duty service members 18 years of age or older. Vitals records were collected to obtain body mass index values. Composite Health Care System laboratory data were queried for hemoglobin A1c (HbA1c) results as well as fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) results. The percentage of active duty service members meeting criteria for prediabetes screening was determined by totaling members age 45 and older with members age 18- to 44-year old with a body mass index ≥25.0 kg/m2, then dividing by the total number of members for each respective military branch. The percentage of active duty service members actually screened for prediabetes was determined based on members meeting prediabetes screening criteria who in fact had FPG, OGTT, or HbA1c labs. The total number of labs meeting prediabetes criteria was determined based on those aforementioned labs with results in the prediabetes range (FPG between 100 and 125 mg/dL, OGTT between 140 and 199 mg/dL, or HbA1c range of 5.7%-6.4%). The total number of service members with appropriate prediabetes International Classification of Disease (ICD) code was determined by identifying members with ICD-9 and ICD-10 codes 790.21, 790.22, and R73.01-R73.03 in their medical record. RESULTS: From 2014 to 2018, 53.9% of 332,502, 56% of 543,081, and 47.3% of 531,313 active duty service members in the Air Force, Army and Navy, respectively, met criteria for prediabetes screening. The rates of actually screening for prediabetes were similar across the Air Force (4.8%), Army (6.7%), and Navy (5.5%). The percentage with labs meeting prediabetes criteria ranged from 17.9% to 28.4% in the Air Force, 24.2% to 30.3% in the Army, and 24.2% to 30.9% in the Navy. The rate of ICD coding for prediabetes increased from 2014 to 2018 across all branches (29.8%-65.3% for the Air Force, 24.6%-46.8% for the Army, and 40.0%-45.5% for the Navy). CONCLUSION: Screening for prediabetes in the active duty military population is grossly inadequate, and even of those screened, diagnosing those meeting prediabetes criteria is similarly inadequate. Although this scenario is not unique to the Military Health System, but reflective of a larger national problem, efforts should be made within the Military Health System to increase the screening for this common disorder. Identifying service members with prediabetes enables opportunities for targeted interventions to delay or prevent the progression to diabetes mellitus

    Physical function and associations with diet and exercise: Results of a cross-sectional survey among elders with breast or prostate cancer

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    BACKGROUND: Functional decline threatens independent living and is common among individuals diagnosed with cancer, especially those who are elderly. The purpose of this study was to explore whether dietary and exercise practices are associated with physical function status among older cancer survivors. METHODS: Mailed surveys were used to ascertain data on physical function, dietary fat, fruit and vegetable (F&V) consumption, and exercise among elderly diagnosed with early stage (I-II) breast (N = 286) or prostate cancer (N = 402) within the past 18 months. RESULTS: Sixty-one percent of respondents reported diets with <30% of energy from fat, 20.4% reported F&V intakes of 5+ daily servings, and 44.6% reported regular vigorous exercise. Significant, independent associations were found between physical functioning and reported dietary fat intake, F&V consumption, and exercise. A simultaneous multiple regression model controlled for age, race, gender, time since diagnosis and concurrent health behaviors yielded the following estimates: (1) 0.2 increase in the SF-36 physical function subscale (PFS) score with each reported 1% decrease in percent energy from fat (p < .0001); (2) 0.9 increase in the SF-36 PFS score for each reported serving of F&V/day (p = .0049); and (3) 15.4 increase in the SF-36 PFS score with a positive response for regular vigorous exercise (p < .0001). CONCLUSIONS: Results of this cross-sectional survey suggest that regular vigorous exercise and consumption of diets low in fat and rich in F&Vs are associated with higher levels of physical functioning among older cancer survivors. Interventions that promote healthful lifestyle change may deliver considerable benefit within this ever increasing and vulnerable population

    Higgs boson studies at the Tevatron

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    This is the publisher's version, also available electronically from http://journals.aps.org/prd/abstract/10.1103/PhysRevD.88.052014.We combine searches by the CDF and D0 Collaborations for the standard model Higgs boson with mass in the range 90–200  GeV/c(2) produced in the gluon-gluon fusion, WH, ZH, tt-barH, and vector boson fusion processes, and decaying in the H→bb-bar, H→W(+)W(−), H→ZZ, H→τ(+)τ(−), and H→γγ modes. The data correspond to integrated luminosities of up to 10  fb(−1) and were collected at the Fermilab Tevatron in pp-bar collisions at s√=1.96  TeV. The searches are also interpreted in the context of fermiophobic and fourth generation models. We observe a significant excess of events in the mass range between 115 and 140  GeV/c(2). The local significance corresponds to 3.0 standard deviations at mH=125  GeV/c(2), consistent with the mass of the Higgs boson observed at the LHC, and we expect a local significance of 1.9 standard deviations. We separately combine searches for H→bb-bar, H→W(+)W(−), H→τ(+)τ(−), and H→γγ. The observed signal strengths in all channels are consistent with the presence of a standard model Higgs boson with a mass of 125  GeV/c(2)

    Search for Charged Massive Long-Lived Particles

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    This is the publisher's version, also available electronically from http://journals.aps.org/prl/abstract/10.1103/PhysRevLett.108.121802.We report on a search for charged massive long-lived particles (CMLLPs), based on 5.2  fb^(−1) of integrated luminosity collected with the D0 detector at the Fermilab Tevatron ppbar collider. We search for events in which one or more particles are reconstructed as muons but have speed and ionization energy loss (dE/dx) inconsistent with muons produced in beam collisions. CMLLPs are predicted in several theories of physics beyond the standard model. We exclude pair-produced long-lived gauginolike charginos below 267 GeV and Higgsino-like charginos below 217 GeV at 95% C.L., as well as long-lived scalar top quarks with mass below 285 GeV

    Combination of measurements of the top-quark pair production cross section from the Tevatron Collider

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    This is the publisher's version, also available electronically from http://journals.aps.org/prd/abstract/10.1103/PhysRevD.89.072001

    Measurement of direct CP violation parameters in B(±)→J/ψK(±) and B(±)→J/ψπ(±) decays with 10.4  fb(−1) of Tevatron data

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    This is the publisher's version, also available electronically from http://journals.aps.org/prl/abstract/10.1103/PhysRevLett.110.241801.We present a measurement of the direct CP-violating charge asymmetry in B(±) mesons decaying to J/ψK(±) and J/ψπ(±) where J/ψ decays to μ(+)μ(−), using the full run II data set of 10.4  fb(−1) of proton-antiproton collisions collected using the D0 detector at the Fermilab Tevatron Collider. A difference in the yield of B(−) and B(+) mesons in these decays is found by fitting to the difference between their reconstructed invariant mass distributions resulting in asymmetries of A(J/ψK)=[0.59±0.37]%, which is the most precise measurement to date, and A(J/ψπ)=[−4.2±4.5]%. Both measurements are consistent with standard model predictions

    Combination of CDF and D0 W-Boson mass measurements

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    This is the publisher's version, also available electronically from http://journals.aps.org/prd/abstract/10.1103/PhysRevD.88.052018
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