50 research outputs found

    Problems of Clinical Research in Shock

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    Hyperglycaemia in critical illness is a risk factor for later development of type II diabetes mellitus

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    Hyperglycaemia caused by stress and inflammation is common during critical illness. We hypothesised that a latent glucose metabolism disturbance contributes to development of hyperglycaemia and that those patients have increased risk for diabetes. We included patients with sepsis, acute coronary syndrome and acute heart failure with no history of impaired glucose metabolism and divided them in the hyperglycaemia group (glucose ≥ 7.8 mmol/l) and normoglycaemia group. Patients were followed for 5 years. Follow-up was completed for 115 patients in the normoglycaemia group, of which 4 (3.5%) developed type 2 diabetes. In the hyperglycaemia group 51 patients finished follow-up and 8 (15.7%) developed type 2 diabetes. Relative risk in 5-year period for patients with hyperglycaemia was 4.51 for development of type 2 diabetes. Patients with hyperglycaemia during critical illness who are not diagnosed with diabetes before or during the hospitalisation should be considered a population at increased risk for developing diabetes

    Stratigraphy of Reinga and Aotea basins, NW New Zealand: constraints from dredge samples on regional correlations and reservoir character

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    <p>Sandstone, mudstone and limestone samples dredged in the Reinga and Aotea basins, NW New Zealand during voyage TAN1312 provide age and lithological constraints on the Cretaceous–Neogene succession. A total of 46 micropaleontology and 7 macropaleontology samples were examined along with 84 thin-sectioned petrographical samples. Some were examined by X-ray diffraction and porosity-permeability analyses. Late Cretaceous sandstones are dominated by feldspathic and lithofeldspathic compositions, with mixed granitic plutoniclastic and volcaniclastic provenance; a comparison with Pakawau Group of Taranaki Basin is appropriate. Late Cretaceous–Paleogene mudstones are widespread and display close petrographical and age similarities to the Whangai Formation facies of other parts of New Zealand and fine-grained carbonate facies of the Weber and Amuri formations of eastern North and South Islands, respectively. Cretaceous limestone and Paleogene sandstone were not recovered. Carbonates and mudstones dominate the Neogene succession of Reinga and Aotea basins; rare Neogene sandstones have feldspatholithic compositions and resemble Waitemata Group sandstones of the northern North Island. In terms of petroleum prospectivity, Cretaceous sandstones represent a potential reservoir facies but are lithic with low permeability.</p
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