A study of the colloidal properties of zirconium and promethium by electrodialysis and liquid-liquid extraction

The purpose of this investigation was to study the solution chemistry of zirconium by investigating the colloidal behavior of natural zirconium and zirconium-95, utilizing electrodialysis and liquid-liquid extraction techniques. Also incorporated into this study was the investigation of optimum conditions for the extraction of the natural zirconium and zirconium-95 with thenoyl trifluoracetone. A limited amount of work was done on the colloidal nature of promethium-147 --Introduction, pages 2-3

Pericardial Thickness Measured With Transesophageal Echocardiography: Feasibility and Potential Clinical Usefulness

AbstractObjectives. This study assessed the reliability of transesophageal echocardiographic measurements of pericardial thickness and the potential diagnostic usefulness of this technique.Background. Transthoracic echocardiography cannot reliably detect thickened pericardium. The superior resolution achieved with transesophageal echocardiography should allow better pericardial definition.Methods. Pericardial thickness measured at 26 locations in 11 patients with constrictive pericarditis who underwent intraoperative transesophageal echocardiography was compared with pericardial thickness measured with electron beam computed tomography. Intraobserver and interobserver variabilities were determined. Pericardial thickness was then measured in 21 normal subjects. With these values as a guide, two observers reviewed 37 transesophageal echocardiographic studies to determine whether echocardiographic measurement of pericardial thickness could be used to distinguish diseased from normal pericardium.Results. The correlation between echocardiographic and computed tomographic measurements (r ≥ 0.95, SE ≤ 0.06 mm, p < 0.0001) was excellent. The ±2 SD limits of agreement were ±1.0 mm or less for pericardial thickness <5.5 mm and ±2.0 mm or less for the entire range of thicknesses. Intraobserver and interobserver agreements were good. Mean normal pericardial thickness was 1.2 ± 0.8 mm (±2 SD) and did not exceed 2.5 mm. Pericardial thickness ≥3 mm on transesophageal echocardiography was 95% sensitive and 86% specific for the detection of thickened pericardium.Conclusions. Measurement of pericardial thickness with transesophageal echocardiography is reproducible and should be a valuable adjunct in assessing constrictive pericarditis.(J Am Coll Cardiol 1997;29:1317–23

The Intersectionality of Religion and SocialWelfare: Historical Development of Richmond\u27s Nonprofit Health and Human Services

Studying the intersectionality of religion and social welfare in Richmond, Virginia requires going back to the beginning of the Virginia colony. In the crucible of the colony, the religious and social welfare functions of a parish community were one and the same. However, after the Revolutionary War it was just a matter of time before the entire system was disassembled. The process of disentanglement of church and state created an identity crisis in Virginia. In the late 1700s, the emergence of charitable efforts began with leading men of Richmond who tried to address the temporary needs of travelers, followed by groups of women who discovered new roles they could play through charitable works. The new “system” became a potpourri of societies, congregations, associations, and county units attempting to provide for the social welfare of the populous. The intersectionality of religion and social welfare continued as a diverse landscape of small and large organizations and congregations performing the social welfare functions in Richmond and throughout the Commonwealth emerged. Today, to attempt to separate the church from the state in this conglomerate of agencies is neither possible nor desirable. However, understanding its’ historical complexity is essential if one is to engage in contemporary practice within Richmond’s health and human service system

Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis.

Background: Many children with pulmonary tuberculosis remain undiagnosed and untreated with related high morbidity and mortality. Recent advances in childhood tuberculosis algorithm development have incorporated prediction modelling, but studies so far have been small and localised, with limited generalisability. We aimed to evaluate the performance of currently used diagnostic algorithms and to use prediction modelling to develop evidence-based algorithms to assist in tuberculosis treatment decision making for children presenting to primary health-care centres. Methods: For this meta-analysis, we identified individual participant data from a WHO public call for data on the management of tuberculosis in children and adolescents and referral from childhood tuberculosis experts. We included studies that prospectively recruited consecutive participants younger than 10 years attending health-care centres in countries with a high tuberculosis incidence for clinical evaluation of pulmonary tuberculosis. We collated individual participant data including clinical, bacteriological, and radiological information and a standardised reference classification of pulmonary tuberculosis. Using this dataset, we first retrospectively evaluated the performance of several existing treatment-decision algorithms. We then used the data to develop two multivariable prediction models that included features used in clinical evaluation of pulmonary tuberculosis-one with chest x-ray features and one without-and we investigated each model's generalisability using internal-external cross-validation. The parameter coefficient estimates of the two models were scaled into two scoring systems to classify tuberculosis with a prespecified sensitivity target. The two scoring systems were used to develop two pragmatic, treatment-decision algorithms for use in primary health-care settings. Findings: Of 4718 children from 13 studies from 12 countries, 1811 (38·4%) were classified as having pulmonary tuberculosis: 541 (29·9%) bacteriologically confirmed and 1270 (70·1%) unconfirmed. Existing treatment-decision algorithms had highly variable diagnostic performance. The scoring system derived from the prediction model that included clinical features and features from chest x-ray had a combined sensitivity of 0·86 [95% CI 0·68-0·94] and specificity of 0·37 [0·15-0·66] against a composite reference standard. The scoring system derived from the model that included only clinical features had a combined sensitivity of 0·84 [95% CI 0·66-0·93] and specificity of 0·30 [0·13-0·56] against a composite reference standard. The scoring system from each model was placed after triage steps, including assessment of illness acuity and risk of poor tuberculosis-related outcomes, to develop treatment-decision algorithms. Interpretation: We adopted an evidence-based approach to develop pragmatic algorithms to guide tuberculosis treatment decisions in children, irrespective of the resources locally available. This approach will empower health workers in primary health-care settings with high tuberculosis incidence and limited resources to initiate tuberculosis treatment in children to improve access to care and reduce tuberculosis-related mortality. These algorithms have been included in the operational handbook accompanying the latest WHO guidelines on the management of tuberculosis in children and adolescents. Future prospective evaluation of algorithms, including those developed in this work, is necessary to investigate clinical performance. Funding: WHO, US National Institutes of Health

un equilibrium

un equilibrium new works by James Hutchinson Private view: Friday 7th March, 6-9pm Live performance from 7 pm Exhibition dates: 7th March – 2nd April 2014 It seems appropriate to make an exhibition of contemporary visual art with a title that does not exist; an existing word might be disequilibrium, A loss or absence of equilibrium pertaining to an economy or lack of equilibrium; imbalance. However this exhibition is not an illustration of the current economic climate or state of contemporary art. It is an experiment of interconnected forms, ideas and sounds to be interpreted by the audience and interfaced through painting, sculpture, installation and electronic software manifesting artwork in relation to sound. James Hutchinson is an artist whose practice encompasses a wide variety of media. Hutchinson has exhibited in many national and international exhibitions. Currently teaching Fine Art at the University of Sunderland, James Hutchinson presents his newest works in a range of appropriate contemporary media, pushing boundaries in relation to media, interactivity, form, sound and space