11 research outputs found
Immunological studies of chromobacterium species by immunodifusion and agglutination methods
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Artigo -Cleômenes Reis - 1976.pdf: 955148 bytes, checksum: b0eff31bd1252691a8d3c4a6d1f53854 (MD5)
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Previous issue date: 1976-12CegrafSegundo referências bibliográficas,
aã bactérias do género Chromobacteriura
exibem considerável heterogenicidade
antigênica, e que os antígenos
somáticos das amostras mesofílicas e
psicrofílicas parecem compl e lamente
distintos.
Tendo sido isolada uma nova amostra
mesofflíca, recentemente, em nosso
meio, fez-se o estudo imunológíco
comparativo entre ela e as amostras
mesofílicas provenientes do Instituto
Pasteur de Paris e Public Health Service,
Atlanta, Georgia, U.S.A. e uma
amostra psicrofflica proveniente do
Instituto Pasteur de Paris.
Houve, nos testes de aglutinação em
lâmina, reaçoes cruzadas entre todas
as amostras estudadas.
Nos testes de imunodifusão em gel
de agar, pelo método de Ouchterlony,
observou-se que a amostra isolada recentemente
em Goiás exibe um antígeno
diferente daqueles existentes nas
demais amostras.The immunological studies by
immunodifusion method demonstrated
antígenic specificity of mesophylic
strain discovered in Goiás,
Brazil (Chromobacterium
goianiensis), comparatively with
others Chromobacterium strains
(Chromobacterium violaceum —
KC 531, Public Health Service,
Atlanta, U.S.A.; and 54.144,
Pasteur Institute, Paris, France:
Chromobacterium lividran,
52.227, Pasteur Institute, Paris,
France) .
On the basis of the findings obtained
in agglutination slide tests
were development of cross teaction,
and it dont be considered
as one of the special techniques
available
Diarrhea of children in Goiânia during summer 1970 a bacteriologic survey of 400 cases
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Artigo - Cleomenes Reis - 1972.pdf: 2265858 bytes, checksum: 2e37acd5c7b6620baaff3f40d1fd57f4 (MD5)
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Artigo - Cleomenes Reis - 1972.pdf: 2265858 bytes, checksum: 2e37acd5c7b6620baaff3f40d1fd57f4 (MD5)
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Artigo - Cleomenes Reis - 1972.pdf: 2265858 bytes, checksum: 2e37acd5c7b6620baaff3f40d1fd57f4 (MD5)
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Artigo - Cleomenes Reis - 1972.pdf: 2265858 bytes, checksum: 2e37acd5c7b6620baaff3f40d1fd57f4 (MD5)
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Previous issue date: 1972-03Os autores estudaram a prevalência de enterobactérias em Goiânia,
durante o verão de 1970, nas fezes de 400 crianças de l mês a
10 anos de idade, atendidas em 2 Hospitais, com diarreia aguda, com
perturbações digestivas e sinais de infecção,
A frequência mais elevada foi de colibacilos (42,6%).
índices também elevados foram encontrados nas infecções pelas
bactérias dos géneros Proteus, Klebsiclla e Shigella.
O grande número de E. Coli cnteropatogênica foi constatada
sorològicamente, havendo predominância de amostras O 111 B 4, 055
B 5, O 26 B 6, e O 126 B 16.
Em todos os casos foram feitos testes de sensibilidade a 15 drogas
antimicrobianas.
O ácido nalidíxico, a gentamicina e a ampicilína mostraram
maior eficácia, "in vitro", contra todas as enterobactérias isoladas que
outros 12 agentes antibacterianos utilizados.The prevalence of intestinal disease causing bactéria during
Summer 1970 was studied. The stools of 400 children with acute
diarrhea from two Hospitais in Goiânia were examined.
The highest incidence was E. coli (42,6%) predominating
the samples: O III B 4, O 55 B 5, and O 126 B 16.
Also great numbcrs of Proteus, Klebsiella and Shigella were
found.
In ali cases susceptibility tests to 15 different antibiotics were
performed.
Nalidixic acid, gentamicin and ampicillín proved more effective
"in vitro" against ali cnteric bactéria than the other 12 antibiotics
tested
Investigation of gram positive, aerobic and pathogenic bactéria in manioc root meal of open-air market in Goiânia
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Artigo - Maria Idalina Marques Tavares - 1977.pdf: 1056381 bytes, checksum: 5e92c8ef2c525781f3ff9d82cdc790ef (MD5)
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Artigo - Maria Idalina Marques Tavares - 1977.pdf: 1056381 bytes, checksum: 5e92c8ef2c525781f3ff9d82cdc790ef (MD5)
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Artigo - Maria Idalina Marques Tavares - 1977.pdf: 1056381 bytes, checksum: 5e92c8ef2c525781f3ff9d82cdc790ef (MD5)
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Previous issue date: 1977-12CegrafEm 30 amostras de farinha de mandioca,
colhidas em feiras livres de
Goiânia, encontrou-se 16,66% de contaminação
por bactérias patogênicas,
sendo que a maior incidência coube
aos Staphy lococcus pyogenes.
Uma das amostras continha Staphylococcus
pyogenes (aureus) e Strepto-
CDCCIM pyogenes, e, apenas uma continha
Pneumococo (D. pneumoniea).When making researcheu for pathogenic
bactérias in floor (mandioca)
solei out on the free markets of
Goiânia, it was found 16,66% of contamination.
The following bactérias in deceasing
order were found: Staphylococcus aureus,
Streptococcus pyogenes and
Pncumococcus.
One of the samples was found to
havc both, Staphylococcus aureus
uru! Streptococcus pyogenes
Labofatory diagnosis of diphteria with a new culture médium, complementation of eugonagar
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Artigo - Mário Diniz - 1972.pdf: 1094384 bytes, checksum: 55003926857bddfa129b0ddf16b8e21b (MD5)
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Artigo - Mário Diniz - 1972.pdf: 1094384 bytes, checksum: 55003926857bddfa129b0ddf16b8e21b (MD5)
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Artigo - Mário Diniz - 1972.pdf: 1094384 bytes, checksum: 55003926857bddfa129b0ddf16b8e21b (MD5)
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Artigo - Mário Diniz - 1972.pdf: 1094384 bytes, checksum: 55003926857bddfa129b0ddf16b8e21b (MD5)
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Previous issue date: 1972-09-30Um novo meio de cultura elaborado
pelos autores permitiu crescimento
seletivo rápido e "luxuriante" de
Corynebacterfum díphteriae.
Para a sua constituição foi utilizado
o Eugonagar Vera (BBL) acrescido
de amido, maltose, plasma hemolizado
de carneiro, vermelho neutro e
solução aquosa de telurito de potássio
a 3%.
Este meio, segundo as observações
dos autores, mostrou-se mais eficiente
do que outros, para detecção de Corynebacterimn.A new culture médium elaborated
by the authors permitted a
quick selective and luxuriant
growtti of Corynebacterium diphteriae
For its constitution they used
Eugoiagar Vera (BBL), and ad-
4ed starch, maltose, hemolyzed
:heep plasma, neutral red and a
J% aqueous solution of potas-
;ium telluríte.
This médium, according to the
zuthors, showed more effectivc
*ian any other in the detection
cf Corynebacterium
Detection, identification and susceptibility to antimycobacterial drugs of mycobacteria from patients with the acquired immunodeficiency syndrome at an AIDS Reference Hospital in Goiás, Brazil
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Artigo - Débora Lemos Maldi Maia - 2000.pdf: 4267574 bytes, checksum: c2b94c5bcb248ae16fb9569ae67a009f (MD5)
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Previous issue date: 2000-12Sociedade Brasileira de ParasitologiaCegrafApós consentimento livre e esclarecido, foram coletadas e analisadas, bacteriologicamente, 116 amostras (líquor, escarro, lavado brônquico, biópsia/punção de gànglio, urina, sangue, biópsia hepática, aspirado de medula óssea e líquido pleural), provenientes de 87 portadores de aids internados ou em acompanhamento no Hospital de Doenças Tropicais do Estado de Goiás (HDT). O material foi submetido à baciloscopia pela técnica de Ziehl-Neelsen e à cultura em dois meios: Lõwenstein-Jensen, L-J, (sólido) e sistema bifásico, BI, (sólido/líquido). A descontaminação foi processada pelos métodos de Petrolf e lauril-sulfato de sódio (SDS). A identificação das micobactérias foi realizada através de provas de crescimento em presença de inibidores, produção de pigmento, tempo de crescimento e provas bioquímicas. Determinou-se a susceptibilidade às drogas antimicobacterianas em todas as cepas deM. tuberculosis obtidas. Foram isoladas micobactérias em 12 (10,3%) das 116 amostras analisadas. Dentre os 12 isolados, nove, provenientes de oito pacientes, foram identificados como M. tuberculosis e os demais, de dois pacientes, como pertencentes ao complexoM. avium (MAC). Uma das cepas deM. tuberculosis, obtida de Hquor, mostrou-se resistente à estreptomicina e outra, de escarro com baciloscopia negativa, apresentou resistência a rifampicina, isoniazida, pirazinamida, estreptomicina, etambutol e etionamida. Das 12 culturas positivas, seis tiveram baciloscopia negativa e o isolamento de duas cepas de MAC só aconteceu no material descontaminado pelo método SDS. Quanto à eficiência dos meios de cultura, não foi possível observar diferença entre os meios L-J e BI.Detection, identification and susceptibility to antimycobacterial drugs of mycobacteria from patients with the acquired immunodeficiency syndrome at an AIDS Reference Hospital in Goiás, Brazil.
ln the present study, 116 samples, including cerebrospinal fluid, sputum, bronchoscopy specimens, lymph node biopsy, urine, blood, tiver biopsy, bone marrow aspirate and pleural liquid were obtained from AIDS in-patients or out-patients followed-up at Hospital de Doenças Tropicais do Estado de Goiás (HDT). Samples were processed for detection of mycobacteria. Acidfast bacillus (AFB) was detected by conventional Ziehl-Neelsen method and cultures were performed by inoculation into a solid medium, LõwensteinJensen (L-J), and biphasic system (BI), consisting of a solid medium (L-J) associated to a liquid medium (7H9). Before culturing, samples were digested and decontaminated with sodium dodecyl sulphate (SOS) and by the Petroff method. Species identification was based on growth in the presence of inhibitory agents, growth rates, colony pigmentation and biochemical tests. M tubercu/osis isolates were tested for susceptibility to antimycobacterial drugs. Tests were performed on L-J by the proportion method established by Canetti. The 116 samples yielded 12 isolates (10,3%). These 12 isolates, included nine M tubercu/osis (from eight patients) and three M avium complex (MAC) strains (from two patients). M. tuberculosis recovered from cerebrospinal fluid was resistant to streptomycin and another one, from a smear-negative sputum, was resistant to rifampicin, isoniazid, pirazinamid, streptomycin, ethambutol and ethionamid. Of 12 culture-positive samples, six were smear-negative and two MAC strains were recovered only after sample decontamination by SOS method. There were no differences between L-J medium and BI on recovery rates of the cultured materiais
Staphylococcus saprophyticus in urinary tract infections of man and woman
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Artigo - Márcia Alves Vasconcelos Rodrigue - 1993.pdf: 1472979 bytes, checksum: 84fa8c4dd8c97450d4a51d1c748bf3e6 (MD5)
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Previous issue date: 1993-12CegrafOs Staphylococcus saprophyticus representam a maioria das amostras (93%) coagulase
negativas e novobiocino-resistentes incidentes no aparelho urinário do homem (3,7,11). É a espécie Grampositíva
mais frequente nas infecções urinárias de mulheres em Case produtiva (15 a 30 anos) podendo ser
causa de infecções urinárias altas, com envolvimento renal (1,3,5,8*15).
Os AÃ. pretenderam determinar a prevalência de S.saprophyticus nas infecções do trato urinário
masculino ao examinar 52 amostras e do feminino 176 amostras, de maneira distinta. Nos homens as
infecções por Staphylococcus aureus foram mais frequentes que as por E. Coli {36,5% contra 19,23%)
enquanto nas mulheres houve maior frequência de infecções por E.coli (29,54%) e menor por
Staphylococcus aureus (15,90%). Staphylococcus saprophyticus no homem apresentaram incidência de
15,38% e nas infecções urinárias da mulher a frequência foi de 16,47%. Alertam, sobre a importância da
identificação desse patógeno que pode ser visto como contaminanle ou confundido com estafilococos
coagulase-negatívos como os Staphylococcus epidermidis (3,9).The Staphylococcus saprophyticus represent the most of coagulase test
negative and novobiocin test resistent samples (93%) incident in the urinary tract of
men (3,7,11) and the same sample is described as the Gram-positive specimen most
frenquent of urinary infection of womem in productive specimen most 30 years old), which canbe the cause of high urinary infection with renal involvement (1,3,5,8,15).
The authors intende to determine the prevalence of 5. saprophyticus in urinary Irart
infection, where were examined in separeted, fifty-two samples of urinary malc tract
and one hundred seventy six (176) of urinary female tract. Infections os men by
Staphylococcus aureus were more frenquent than E. coli (36,5% against 19,23%),
while in women was sensible the difference between the biggest frenquency of
infection by E. coli (29,54%) and less by Staphylococcus aureus 915,90% and in
infections of urinary tract of women the frequency was 16,47%. Again, the authors
world like to conclude their research by emphasizing the importance of identificaiion
of this pathogenous, what can be seen as cause of contamination or confuscd with
Staphylococcus coagulase test negative as the Staphylococcus epidermidis (3,9)
Children gastroenteritis: bacteríologycal analysis, 1986 - 1990. "Goiânia - Goiás", Brazil
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Artigo- Maria Aparecida Muniz Cavalcante - 1992.pdf: 1161474 bytes, checksum: 96d9fe365f9efc4b39259533a9887422 (MD5)
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Previous issue date: 1992-06CegrafForam estudadas amostras fecais de 494 crianças de ambos os sexos hospitalizadas com gastrenterite
infantil.
Os casos eram sintomáticos- Alguns pacientes foram hospitalizados com diarreia, enquanto
outros provavelmente desenvolveram a gastrenterite no hospital.
A análise bacteriológica revelou 263 casos positivos. Ocorreram 3 casos de infecção mista, ou
seja a descoberta de mais de um patógeno na mesma amostra de fezes. A bactéria predominante foi a E.
coU enteropatogênica clássica ou EPEC, com 151 casos (57,4%), seguindo-seaf. cofi enteroinvasora ou
EIEC, com 52 (19,3%), Shigella sp. 41 (\5,4%)eSalmonelIa typhimurium()4(\,5%), entre as enterobacteriáceas.
11 amostras de Pseudomonas aeruginosa, 3 à&Pseitdotnonas Cepoceae e umadeStaphylacoccus
áureas constituíram-se entre as outras bactérias virulentas encontradas.
Nos outros 231 casos (amostras negativas para bactérias intestinais patogênicas) foram observadas
bactérias da microbiota intestinal normal, Rotavírus, Adenovírus, Protozoários e Helmintos(2).
Não foram feitos procedimentos para análise de E. co!i toxigênica LT e ST nem pesquisa de
Cryptosporidium.494 fecal samples originating from children living in "Goiânia -
(Goiás)" - Brazil were bacteriologycal analysed. Enteropathogenic Classic
E. coli were found in 263 positive cultures for pathogenic bactéria (57,4%);
Enteropathogenic invasible E. coli 52 (19,3%); Shigella sp 41 (15,4%); Salmonella
typhimurium 4 (1,5%). In 16 cases Pseudomonas sp were detected 224
bactéria! culture were negatives for pathogens, were found members of normal
intestinal flora. These numbers are discussed
Evaluation of cytokines in endocervical secretions of women with candidiasis, trichomoniasis or bacterial vaginitis
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Artigo -Ana Claudia Camargo Campos - 2011.pdf: 468452 bytes, checksum: d62291d28a51fbb42cc404530fbfee67 (MD5)
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Previous issue date: 2011-05Sociedade Brasileira de ParasitologiaCegrafOs processos infecciosos na vagina devidos a micro-organismos são muito comuns. As
vulvovaginites são, em grande parte, causadas por protozoários, leveduras, bactérias e/ou vírus. Sua
erradicação ou contenção é normalmente mediada pelas citocinas da mucosa vaginal. O presente
estudo teve a intenção de verificar a concentração de citocinas IL-2, IL-6, IL-10, IL-12, IFN-γ, TNF-α
e suas relações com alguns dos agentes das infecções. Foram incluídas 173 mulheres sexualmente
ativas com idade entre 16 e 48 anos, média de 31,4 ± 6,5 anos, as quais foram divididas nos seguintes
grupos: controle, com candidíase, com tricomoníase e com vaginite bacteriana. As amostras foram
submetidas ao cultivo e, posteriormente, à identificação do micro-organismo. Em seguida, foi feita a
dosagem de citocinas da secreção endocervical por meio do teste ELISA. Os dados foram submetidos
à análise estatística, calculando-se a mediana e o intervalo interquartil, e ao teste Mann-Whitney.
Os resultados foram considerados significantes com p < 0,05. Verificou-se uma maior concentração
de diferentes citocinas no trato genital inferior de mulheres com candidíase, tricomoníase, vaginite
bacteriana do que naquelas com microbiota normal. No grupo controle, foram incluídas 60 (34,7%)
mulheres; nos outros grupos, 19 (11,0%) apresentavam somente candidíase; 3 (1,7%), somente
tricomoníase e 10 (5,8%), vaginite bacteriana; as demais apresentaram outras intercorrências como
HPV ou vaginose bacteriana, entretanto não foi realizado o estudo destes casos ou da sua associação
com os demais grupos. IL-2 e IL-12 mostraram-se significativamente elevadas na presença de
candidíase, quando comparadas ao grupo controle, com p = 0,01 e p = 0,07, respectivamente. As
pacientes com vaginite bacteriana também apresentaram níveis expressivamente aumentados com
p=0,03 para IL-2 e p=0,04 para IL-12. O TNF-α mostrou-se elevado na presença de tricomoníase, com p = 0,04. Os resultados encontrados permitem sugerir que pacientes com diferentes infecções
vaginais apresentam alterações na concentração de algumas citocinas.Infectious processes in the vagina due to infectious micro-organisms are very
common. Vulvovaginitis is commonly caused by protozoa, yeasts, bacteria and/or
viruses and their eradication or containment are usually mediated by cytokines of
the vaginal mucosa. In this study, the intention was to measure the concentration of cytokines IL-2, IL-6, IL-10, IL-12, IFN-γ and TNF-α and their relationship with
some of the infections. One-hundred and seventy three women were included, with
ages between 16 and 48 years (mean=31.4 ± 6.5 years). They were distributed
into four groups: control, candidiasis, trichomoniasis and bacterial vaginitis
group. The samples were subsequently submitted to culture and identification of
micro-organism, followed by cytokine measurements. The data was submitted to
statistical analysis. Median, interquartile range and the Mann-Whitney test was
employed and considered significant when p<0.05. The levels of cytokines in the
lower genital-tract of women with candidiasis, trichomoniasis, bacterial vaginitis
were higher than those with normal flora. Sixty (34.7%) women were in the control
group, 19 (11.0%) presented only candidiasis, three (1.7%) presented trichomoniasis,
and only ten presented (5.8%) bacterial vaginosis. The remaining participants had
comorbidities such as HPV or bacterial vaginosis, although the study of these last
two or association with other conditions was not performed. IL-2 and IL-12 were
significantly elevated in the presence of candidiasis, compared with the control group
p=0.01 and p=0.07, respectively. Patients with bacterial vaginitis also had statistically
significant increased levels for IL-2 (p=0.03) and for IL-12 (p=0.04). TNF-α was
elevated only in the presence of trichomoniasis p=0.04. We concluded that patients
with vaginal infections had an increase in the concentrations of some cytokines
Prevalent microbiota in nose and throat of schoolchildren (5-10 years old) with different li vês patterns
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Previous issue date: 1990-12CegrafOs autores pretenderam observar a presença de microrganismos patogènicos e potencialmente
patogénicos independentemente de sexo e de estações climáticas, participantes da microbiota das oro e
nasofarínge de escolares na faixa etária de 5-10 anos, de estabelecimentos de ensino localizados nas regiões
central e periférica de Goiânia. Os padrões (denominados no trabalho de A e B, respectivamente)
foram estudados e resultaram de níveis sócio-econômicos diferentes, estado nutricional e escolaridade
em índices opostos (2).
Os pequenos grupos de crianças 143 e 136 foram aleatoriamente incluídos na experiência, a
partir de um total relativamente grande, ou seja, de cerca de 8.045 alunos de escolas particulares e 29.162
alunos matriculados em escolas públicas, de março a novembro de 1989.
Os resultados das culturas foram semelhantes, não havendo diferenças significativas entre as
frequências dos microrganismos em um e outro grupo.
A frequência de estreptococos hemolíticos e estafilococos virulentos foram semelhantes em
ambos os grupos nas mesmas estações climáticas.
Staphylococcus áureas potencialmente patogènicos, foram encontrados com incidências muito
elevadas, também em ambos os grupos.The authors intended to observe the presence of pathogenic and
potentially pathogenic microorganisms participants of microbiota of nose and
throat schoolchildren (5-10 years of age) in schools located in the downtown
área and outskirts of Goiânia. The standards (respectively denominated A and
B) were studied and resulted from different económica! classes, nutritional
conditions and opposite school performances.
The children in small groups of 143 and 136 were randomly included
in the experiment and carne from a relatively large group of 8.045 private
schoolchildren and 29.162 public schoolchildren, from March to November of
1989.
The results of culture were similar, not presenting any significant
differences in frequency of microorganisms in either of the groups.
The frequency of hemoliticus Streptococcus and pathogenic
Staphylococcus were similar in both group in the same weather conditions.
The Staphylococcus aureus, potentially pathogenic, were found with
high leveis of incidence in both groups
Meningococcal disease in Goiás — epidemiological date over 1971 to 1974
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Previous issue date: 1975-09CegrafSão apresentados os principais dados
epidemiológicos da Doença Meningocócica
em Goiânia e área de afluência
no período 1971-1574, com
base na casuística do Hospitai "Oswaldo
Cruz" de Doenças Transmissíveis.
1. Ocorrência em relação ao total
anual de internações: em 1971,
33 casos dentre 765 internações
(4,3%); em 1972, 62/1.190
(5,4%>; em 1973, 300/1.728
<17,3%) e 1974, 1.078/2.432
(44,3%).
2. Ocorrência dentre as meningites
de todas as etiologias: em 1971,
33 casos dentre 167 (19,76%);
em 1972, 62/250, (24,80%); em
1973, 300/542 (55,31%); em
1974, 1.078/1.646 (65,48%).
3. Coeficiente de morbídade em Goiânia:
em 1971, 4,13 casos poi
100 mil habitantes; em 1972,
6,52; em 1973, 33,30 c em 1974,
150,04.
4. Coeficiente de mortalidade em
Goiânia: em 1971, 0,97 óbitos
por 100 mil habitantes; em 1972,
1,12; em 1973, 4,60 e em 1974,
13,13.
5. Coeficiente de letalidade: em
1971 faleceram 8 pacientes dentre
33(24,24%); em 1972, 11/62
(17,74%) em 1973, 41/300
(13,66%) e em 1974, 109/1.078
(10,11%).
6. Distribuição mensal: homogénea
em 1971; tendência ascencional
em 1972, 1973 e 1974, a partir
de maio, apresentando maior incidência
no período de agosto a
dezembro com acme em setembro
e outubro.
7. Distribuição por grupo etário:
1971 e 1972 predominou em
criança abaixo de 5 anos e em
1973 e 1974, em crianças acima
de 5 anos e adultos.8. Sorotipos: em 1973 predominou
o Sorotipo C e em 1974 o A.
Concluem que os dados apresentados
caracterizaram uma situação epidêmica
a partir de 1973, que, em
1974, levou a Meningite Meningocócica
a ocupar o 1°. lugar dentre as
doenças transmissíveis que exigem internação
hospitalar, constituindo-se atuahnente
numa doença de grande risco
para a população infanto-juvenil
e que os dados disponíveis até dezembro
de 1974 nos permitem ainda
uma avaliação epidemiológica da vacinação,The principal epidemlology data of
Meningococcic Meningitis in Goiânia
and its surroundings, are shown here.
These data were collectod gut
were 1971-1974, and based on tht
number of in pafients of the "Osw»Ido
Cruz" Hospital for contagiou* dlseascs.
1. Occurence of the disease in relation
to the annual number of patients
interned: in 1971, 33 cases In 765 Interned
patients (4,3%); in 1972
62/1.190 (5,4%); in 1973 300/1.728
(17,3%), and 1974, 1.078/2.432
(44,3%).
2. Occurrence wíthin meníngitli of
ali etiology; in 1971, 33 cases In 167
(19,76%); in 1972, 1.078/1.646
(65,48%,.
3. Morhidity coefficient in Goiânia:
in 1971, 4.13 casei per 100.000
inhabitants; in 1972, 6.52; in 1973,
33,30 and in 1974 150.04.
4. Mortality coefficient in Goiânia;
in 1971, 0,97 per 100.000 Inhabitmti
in 1972, 1.12; in 1973, 4.60 and fn
1974, 15.60. 5. Leíhality coefficient: in 1972* 8
patients died from 33 (24,24%), in
1972, II out o£ 62 (17,74%); in 1973,
41 out of 300 (13,66%) and in 1974,
109 out of 1.073 (10.11%).
6. Moothly distribution: Homogeneus
in 1971; Rising tendency in
1972; 1973 and 1974 beginning in
may and with the peak in the period
.of August to December.
7. Age distribution: children under
5 years old were predominant in
1971 - 1972. Children (aboye 5 years
old and adults predominai in 1973 •
iy?4),
8. - Serotype C:. serotype was predominant
in 1973 and A in 1974.
These data are characteristic of an
Cpidemy since 1973. In 1974, meningococcal
meningitis, was the main contagious
disease that required internaticn.
Now it constitutes a. high nsk
disease for children and young
adults. Data available up to December
1974 do not allow ns to made an
epidemiological eyaluatíon of the vaccination