Cellular Blood Flow

The fluid dynamics video that is presented here outlines recent advances in the simulation of multiphase cellular blood flow through the direct numerical simulations of deformable red blood cells (RBCs) demonstrated through several numerical experiments. Videos show particle deformation, shear stress on the particle surface, and the formation of particle clusters in both Hagen-Poiseuille and shear flow.Comment: 2 pages, one hyperlink to 2 video

Age and helium content of the open cluster NGC 6791 from multiple eclipsing binary members. I. Measurements, methods, and first results

Earlier measurements of the masses and radii of the detached eclipsing binary V20 in the open cluster NGC 6791 were accurate enough to demonstrate that there are significant differences between current stellar models. Here we improve on those results and add measurements of two additional detached eclipsing binaries, the cluster members V18 and V80. The enlarged sample sets much tighter constraints on the properties of stellar models than has hitherto been possible, thereby improving both the accuracy and precision of the cluster age. We employed (i) high-resolution UVES spectroscopy of V18, V20 and V80 to determine their spectroscopic effective temperatures, [Fe/H] values, and spectroscopic orbital elements, and (ii) time-series photometry from the Nordic Optical Telescope to obtain the photometric elements. The masses and radii of the V18 and V20 components are found to high accuracy, with errors on the masses in the range 0.27-0.36% and errors on the radii in the range 0.61-0.92%. V80 is found to be magnetically active, and more observations are needed to determine its parameters accurately. The metallicity of NGC 6791 is measured from disentangled spectra of the binaries and a few single stars to be [Fe/H]= +0.29 \pm 0.03 (random) \pm 0.07 (systematic). The cluster reddening and apparent distance modulus are found to be E(B - V) = 0.160 \pm 0.025 and (m - M)V = 13.51 \pm 0.06 . A first model comparison shows that we can constrain the helium content of the NGC 6791 stars, and thus reach a more accurate age than previously possible. It may be possible to constrain additional parameters, in particular the C, N, and O abundances. This will be investigated in paper II.Comment: Accepted for publication in A&

Absolute dimensions of solar-type eclipsing binaries. EF Aquarii: a G0 test for stellar evolution models

Recent studies have shown that stellar chromospheric activity, and its effect on convective energy transport in the envelope, is most likely the cause of significant radius and temperature discrepancies between theoretical evolution models and observations. We aim to determine absolute dimensions and abundances for the solar-type detached eclipsing binary EF Aqr, and to perform a detailed comparison with results from recent stellar evolutionary models. uvby-beta standard photometry was obtained with the Stromgren Automatic Telescope. The broadening function formalism was applied on spectra observed with HERMES at the Mercator telescope in La Palma, to obtain radial velocity curves. Masses and radii with a precision of 0.6% and 1.0% respectively have been established for both components of EF Aqr. The active 0.956 M_sol secondary shows star spots and strong Ca II H and K emission lines. The 1.224 M_sol primary shows signs of activity as well, but at a lower level. An [Fe/H] abundance of 0.00+-0.10 is derived with similar abundances for Si, Ca, Sc, Ti, V, Cr, Co, and Ni. Solar calibrated evolutionary models such as Yonsei-Yale, Victoria-Regina and BaSTI isochrones and evolutionary tracks are unable to reproduce EF Aqr, especially for the secondary, which is 9% larger and 400 K cooler than predicted. Models adopting significantly lower mixing length parameters l/H_p remove these discrepancies, as seen in other solar type binaries. For the observed metallicity, Granada models with a mixing length of l/H_p=1.30 (primary) and 1.05 (secondary) reproduce both components at a common age of 1.5+-0.6 Gyr. Observations of EF Aqr suggests that magnetic activity, and its effect on envelope convection, is likely to be the cause of discrepancies in both radius and temperature, which can be removed by adjusting the mixing length parameter of the models downwards.Comment: 11 pages, 8 figures, accepted for publication by A&

Production of superpositions of coherent states in traveling optical fields with inefficient photon detection

We develop an all-optical scheme to generate superpositions of macroscopically distinguishable coherent states in traveling optical fields. It non-deterministically distills coherent state superpositions (CSSs) with large amplitudes out of CSSs with small amplitudes using inefficient photon detection. The small CSSs required to produce CSSs with larger amplitudes are extremely well approximated by squeezed single photons. We discuss some remarkable features of this scheme: it effectively purifies mixed initial states emitted from inefficient single photon sources and boosts negativity of Wigner functions of quantum states.Comment: 13 pages, 9 figures, to be published in Phys. Rev.

Changes in intracellular ion activities induced by adrenaline in human and rat skeletal muscle

To study the stimulating effect of adrenaline (ADR) on active Na+/K+ transport we used double-barrelled ion-sensitive micro-electrodes to measure the activities of extracellular K+ (aKe) and intracellular Na+ (aNai) in isolated preparations of rat soleus muscle, normal human intercostal muscle and one case of hyperkalemic periodic paralysis (h.p.p.). In these preparations bath-application of ADR (10−6 M) resulted in a membrane hyperpolarization and transient decreasesaKe andaNai which could be blocked by ouabain (3×10−4 M). In the h.p.p. muslce a continuous rise ofaNai induced by elevation ofaKe to 5.2 mM could be stopped by ADR. In addition, the intracellular K+ activity (aKi), the free intracellular Ca2+ concentration (pCai) and intracellular pH (pHi) were monitored in rat soleus muscle. During ADRaKi increased, pHi remained constant and intracellular Ca2+ apparently decreased. In conclusion, our data show that ADR primarily stimulates the Na+/K+ pump in mammalian skeletal muscle. This stimulating action is not impaired in the h.p.p. muscle

Multi-site H-bridge breathers in a DNA--shaped double strand

We investigate the formation process of nonlinear vibrational modes representing broad H-bridge multi--site breathers in a DNA--shaped double strand. Within a network model of the double helix we take individual motions of the bases within the base pair plane into account. The resulting H-bridge deformations may be asymmetric with respect to the helix axis. Furthermore the covalent bonds may be deformed distinctly in the two backbone strands. Unlike other authors that add different extra terms we limit the interaction to the hydrogen bonds within each base pair and the covalent bonds along each strand. In this way we intend to make apparent the effect of the characteristic helicoidal structure of DNA. We study the energy exchange processes related with the relaxation dynamics from a non-equilibrium conformation. It is demonstrated that the twist-opening relaxation dynamics of a radially distorted double helix attains an equilibrium regime characterized by a multi-site H-bridge breather.Comment: 27 pages and 10 figure