Data collection tool.

(PDF)</p

Informed consent sheet.

(PDF)</p

Standard algortihm for routine COVID-19 testing in Cameroon.

COVID-19: Coronavirus Disease 2019.</p

Study information sheet.

(PDF)</p

Network for COVID-19 testing laboratories.

COVID-19: Coronavirus Disease 2019.</p

Additional file 1: Figure S1. of Early antiretroviral treatment (eART) limits viral diversity over time in a long-term HIV viral suppressed perinatally infected child

Neighborg phylogenetic tree constructed on the pol gene sequences of 400 isolates and additional 163 HIV-1 subtype references. The bar at the bottom indicating 0.01 nucleotide substitution per site. Bootstrap support >90% were showed along the branches. Isolates of sutypes C are shown in red. The sequences involved in mother to child transmission chain are in bold red. (PPTX 160 kb)

Proportion of protease inhibitors resistance-associated mutations with the L76V mutation in HIV-1 subtype B samples and in HIV-1 “non-B” samples.

<p>P-values are indicated only if significant.</p

Prevalence of the L76V mutation between 1998 and 2010 in a database containing 29,643 sequences issued from clinical samples with any antiretroviral drug resistance.

<p>Prevalence of the L76V mutation between 1998 and 2010 in a database containing 29,643 sequences issued from clinical samples with any antiretroviral drug resistance.</p

Population characteristics of patients infected with HIV-1 subtype B and HIV-1 “non-B” subtypes with L76V protease mutation.

*<p>Continuous variables were expressed as median and interquartile range (IQR) and categorical variables were expressed as numbers and percentages.</p><p>95% CI: 95% Confidence Interval; ARV: antiretroviral; PI: protease inhibitor.</p

Dendrograms obtained from average linkage hierarchical agglomerative clustering, showing significant clusters of L76V protease inhibitors resistance mutations among B subtype sequences (A), and among “non-B” subtype sequences (B).

<p>The length of branches reflects distances between mutations in the original distance matrix. Bootstrap values, indicating the significance of clusters, are reported in the boxes.</p