Epidemiological aspects of postoperativelumbar incisional hernias

Department of Urology and Surgical Nephrology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Republic of Moldova, The 8th International Medical Congress for Students and Young Doctors, September 24-26, 2020Introduction. Incisional lumbar hernia is a complication of 17.1% of the surgery on the kidneys and ureter and constitutes 8% of the total hernias of the antero-lateral abdominal wall. Aim of the study. Evaluation of incidence of lumbar incisional hernias following urological surgery and establishment of epidemiological data for a period of 1 year. Materials and methods.. The study developed 32 care patients who underwent surgery on the kidneys with dynamic surveillance up to 12 months. In the case of studies or evaluation of indices such as serum glycemia, the diagnosis of obesity has been established, through the use (BMI) and anthropometric indices of patients. Results. Results. The study shows that in 94% of patients the risk of developing postoperative hernias is increased in the first year after the surgery, considering a significant exceedance of BMI standards, positive uroculture, the presence of diabetes or high blood sugar levels. Thus, the study shows that the lombotomy failure rate represents 11% of the cases. Conclusions. The incidence of incisional hernias at 6 months was 10%, at 12 months the incidence of 18%. The postoperative evolution of patients at increased risk of herniation is uncertain and depends on the presence of risk factors such as diabetes, obesity, anthropometric indices. Diabetes has a significant value in the diagnosis and prophylaxis of incisional hernias

High serum unconjugated bilirubin levels in a patient with mutations in the UGT1A1 gene – clinical case presentation

Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of MoldovaBackground. The UGT1A1 gene plays a significant role in the glucuronidation of bilirubin, and the mutations of this gene lead to limitations in the synthesis of the glucuronyltransferase enzyme, which contributes to the increase in free serum bilirubin. This clinical condition is called Gilbert's syndrome. The patient with Gilbert syndrome has no clinical manifestations until the second decade of life. Scientific studies demonstrate that free serum bilirubin in patients with Gilbert syndrome is almost entirely unconjugated. We present the case study of a 17-year-old patient with Gilbert's syndrome, confirmed by molecular genetics tests