Bidirectional ventricular tachycardia with alternating right and left bundle branch block morphology in a patient with metastatic cardiac tumors

A case is reported of bidirectional ventricular tachycardia and syncope in a 16-year-old male with a previous history of a paratesticular rhabdomyosarcoma that achieved complete remission with treatment. At the electrophysiological study, frequent ectopy of both right and left bundle branch block pattern were present, with runs of monomorphic and bidirectional VT alternating the two morphologies. the study suggested a single focus at the interventricular septum with two exit sites, depolarizing the right and left ventricle in an alternate fashion. Reassessment of the malignancy status showed multiple cardiac metastases with a 4 mm nodule at the interventricular septum.Fed Univ São Paulo, Paulista Sch Med, Dept Clin Cardiac Electrophysiol, São Paulo, SP, BrazilFed Univ São Paulo, Paulista Sch Med, Dept Clin Cardiac Electrophysiol, São Paulo, SP, BrazilWeb of Scienc

Skin iron deposition characterises lipodermatosclerosis and leg ulcer

Background: It is commonly reported that chronic venous disease (CVD) increases the skin iron content in which the excess is stored as haemosiderin. Despite increasing interest in the rote of haemosiderin in venous ulceration, no study has systematically evaluated the occurrence of iron overload in the limbs of patients with CVD. Purpose: To evaluate skin haemosiderin deposition in relation to the presence and severity of skin changes in CVD legs designated according to the clinical, etiologic, anatomic and pathophysiologic (CEAP) classification. Methods: A total of 85 skin biopsies were taken from the medial aspect of 49 limbs with CVD of CEAP clinical stages C2, C3, C4 and C6. The content of ferric ions was assessed by Pert's Prussian Blue (PPB) stain. Results: No haemosiderin deposition was found in normal skin of C2, C3 and C4A legs, in less severe regions of pigmentation and in some parts of more severely affected limbs. Haemosiderin was always present in lipodermatosclerotic skin and ulcers. Occasionally, haemosiderin was found in the apparently normal perilesional skin of C4b and C6 legs. The regenerating dermis at the base of healing ulcers showed none or light haemosiderin deposition. Conclusion: Iron overload is not present in the less severe stages of skin damage due to CVD but lipodermatosclerosis and leg ulcers are always accompanied by haemosiderin deposition. In fact, no severe skin changes occur in CVD legs until iron overload occurs. Our results are in agreement with previous reports suggesting that a genetic inability to counteract skin iron overload is present in these patients. A more detailed analysis of disordered iron metabolism should be undertaken in CVD patients. (C) 2010 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved

AUTOMATIC IMPLANTABLE DEFIBRILLATOR WITH VVI PACEMAKER in A PATIENT WITH CHRONIC CHAGAS MYOCARDITIS and TOTAL ATRIOVENTRICULAR-BLOCK

PRESBYTERIAN MED CTR PHILADELPHIA,PHILADELPHIA HEART INST,39TH & MARKET ST,PHILADELPHIA,PA 19104ESCOLA PAULISTA MED SCH,HOSP São Paulo,DIV CLIN CARDIAC ELECTROPHYSIOL,BR-04023 São Paulo,SP,BRAZILESCOLA PAULISTA MED SCH,HOSP São Paulo,DIV CLIN CARDIAC ELECTROPHYSIOL,BR-04023 São Paulo,SP,BRAZILESCOLA PAULISTA MED SCH,HOSP São Paulo,DIV CLIN CARDIAC ELECTROPHYSIOL,BR-04023 São Paulo,SP,BRAZILWeb of Scienc

CONTROL of MULTIFORM VENTRICULAR-TACHYCARDIA BY PROPRANOLOL in A CHILD WITH NO IDENTIFIABLE CARDIAC DISEASE and SUDDEN-DEATH

HOSP São Paulo,DIV CLIN CARDIAC ELECTROPHYSIOL,São Paulo,BRAZILPRESBYTERIAN MED CTR,PHILADELPHIA HEART INST,PHILADELPHIA,PAHOSP São Paulo,DIV CLIN CARDIAC ELECTROPHYSIOL,São Paulo,BRAZILWeb of Scienc

Early chronotropic response analysis in head up tilt table test

Universidade Federal de São Paulo, Arrhythmia Ctr, Albert Einstein Hosp, São Paulo, BrazilUniversidade Federal de São Paulo, Arrhythmia Ctr, Albert Einstein Hosp, São Paulo, BrazilWeb of Scienc

ANGIOGRAPHIC and ELECTROPHYSIOLOGIC SUBSTRATES of VENTRICULAR-TACHYCARDIA in CHRONIC CHAGASIC MYOCARDITIS

PRESBYTERIAN MED CTR PHILADELPHIA,PHILADELPHIA HEART INST,39TH & MARKET ST,PHILADELPHIA,PA 19104ESCOLA PAULISTA MED SCH,HOSP São Paulo,DIV CLIN CARDIAC ELECTROPHYSIOL,BR-04023 São Paulo,SP,BRAZILESCOLA PAULISTA MED SCH,HOSP São Paulo,DIV CLIN CARDIAC ELECTROPHYSIOL,BR-04023 São Paulo,SP,BRAZILWeb of Scienc