1,415 research outputs found

    The Pure State Space of Quantum Mechanics as Hermitian Symmetric Space

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    The pure state space of Quantum Mechanics is investigated as Hermitian Symmetric Kaehler manifold. The classical principles of Quantum Mechanics (Quantum Superposition Principle, Heisenberg Uncertainty Principle, Quantum Probability Principle) and Spectral Theory of observables are discussed in this non linear geometrical context.Comment: 18 pages, no figure

    Supersymmetric Extension of the Minimal Dark Matter Model

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    The minimal dark matter model is given a supersymmetric extension. A super SU(2)L quintuplet is introduced with its fermionic neutral component still being the dark matter, the dark matter particle mass is about 19.7 GeV. Mass splitting among the quintplet due to supersymmetry particles is found to be negligibly small compared to the electroweak corrections. Other properties of this supersymmetry model are studied, it has the solutions to the PAMELA and Fermi-LAT anomaly, the predictions in higher energies need further experimental data to verify.Comment: 14 pages, 7 figures, accepted for publication in Chinese Physics C, typos correcte

    Sterile neutrinos, lepton asymmetries, primordial elements: how much of each?

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    We investigate quantitatively the extent to which having a primordial leptonic asymmetry (n_nu \neq n_nubar) relaxes the bounds on light sterile neutrinos imposed by BBN and LSS. We adopt a few assumptions that allow us to solve the neutrino evolution equations over a broad range of mixing parameters and asymmetries. For the general cases of sterile mixing with the electron or muon neutrino, we identify the regions that can be reopened. For the particular case of a LSND-like sterile neutrino, soon to be rejected or confirmed by MiniBooNE, we find that an asymmetry of the order of 10^-4 is needed to lift the conflicts with cosmology.Comment: 18 pages, 2 figures. v2: References and minor comments added. Matches version published on PR

    Sustainable water resources management for irrigated agriculture in Latin America

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    [No abstract available]EU/FP

    The Casimir force on a surface with shallow nanoscale corrugations: Geometry and finite conductivity effects

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    We measure the Casimir force between a gold sphere and a silicon plate with nanoscale, rectangular corrugations with depth comparable to the separation between the surfaces. In the proximity force approximation (PFA), both the top and bottom surfaces of the corrugations contribute to the force, leading to a distance dependence that is distinct from a flat surface. The measured Casimir force is found to deviate from the PFA by up to 15%, in good agreement with calculations based on scattering theory that includes both geometry effects and the optical properties of the material

    Can multistate dark matter annihilation explain the high-energy cosmic ray lepton anomalies?

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    Multistate dark matter (DM) models with small mass splittings and couplings to light hidden sector bosons have been proposed as an explanation for the PAMELA/Fermi/H.E.S.S. high-energy lepton excesses. We investigate this proposal over a wide range of DM density profiles, in the framework of concrete models with doublet or triplet dark matter and a hidden SU(2) gauge sector that mixes with standard model hypercharge. The gauge coupling is bounded from below by the DM relic density, and the Sommerfeld enhancement factor is explicitly computable for given values of the DM and gauge boson masses M, mu and the (largest) dark matter mass splitting delta M_{12}. Sommerfeld enhancement is stronger at the galactic center than near the Sun because of the radial dependence of the DM velocity profile, which strengthens the inverse Compton (IC) gamma ray constraints relative to usual assumptions. We find that the PAMELA/Fermi/H.E.S.S. lepton excesses are marginally compatible with the model predictions, and with CMB and Fermi gamma ray constraints, for M ~ 800 GeV, mu ~ 200 MeV, and a dark matter profile with noncuspy Einasto parameters alpha > 0.20, r_s ~ 30 kpc. We also find that the annihilating DM must provide only a subdominant (< 0.4) component of the total DM mass density, since otherwise the boost factor due to Sommerfeld enhancement is too large.Comment: 20 pages, 12 figures; v2: Corrected branching ratio for ground state DM annihilations into leptons, leading to boost factors that are larger than allowed. Added explicit results for doublet DM model. Some conclusions changed; main conclusion of tension between inverse Compton constraints and N-body simulations of halo profiles is unchange

    Alterations in vasodilator-stimulated phosphoprotein (VASP) phosphorylation: associations with asthmatic phenotype, airway inflammation and β\u3csub\u3e2\u3c/sub\u3e-agonist use

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    Background Vasodilator-stimulated phosphoprotein (VASP) mediates focal adhesion, actin filament binding and polymerization in a variety of cells, thereby inhibiting cell movement. Phosphorylation of VASP via cAMP and cGMP dependent protein kinases releases this brake on cell motility. Thus, phosphorylation of VASP may be necessary for epithelial cell repair of damage from allergen-induced inflammation. Two hypotheses were examined: (1) injury from segmental allergen challenge increases VASP phosphorylation in airway epithelium in asthmatic but not nonasthmatic normal subjects, (2) regular in vivo β2-agonist use increases VASP phosphorylation in asthmatic epithelium, altering cell adhesion. Methods Bronchial epithelium was obtained from asthmatic and non-asthmatic normal subjects before and after segmental allergen challenge, and after regularly inhaled albuterol, in three separate protocols. VASP phosphorylation was examined in Western blots of epithelial samples. DNA was obtained for β2-adrenergic receptor haplotype determination. Results Although VASP phosphorylation increased, it was not significantly greater after allergen challenge in asthmatics or normals. However, VASP phosphorylation in epithelium of nonasthmatic normal subjects was double that observed in asthmatic subjects, both at baseline and after challenge. Regularly inhaled albuterol significantly increased VASP phosphorylation in asthmatic subjects in both unchallenged and antigen challenged lung segment epithelium. There was also a significant increase in epithelial cells in the bronchoalveolar lavage of the unchallenged lung segment after regular inhalation of albuterol but not of placebo. The haplotypes of the β2-adrenergic receptor did not appear to associate with increased or decreased phosphorylation of VASP. Conclusion Decreased VASP phosphorylation was observed in epithelial cells of asthmatics compared to nonasthmatic normals, despite response to β-agonist. The decreased phosphorylation does not appear to be associated with a particular β2-adrenergic receptor haplotype. The observed decrease in VASP phosphorylation suggests greater inhibition of actin reorganization which is necessary for altering attachment and migration required during epithelial repair

    Sleep, aging, and lifespan in Drosophila

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    <p>Abstract</p> <p>Background</p> <p>Epidemiological studies in humans suggest that a decrease in daily sleep duration is associated with reduced lifespan, but this issue remains controversial. Other studies in humans also show that both sleep quantity and sleep quality decrease with age. <it>Drosophila melanogaster </it>is a useful model to study aging and sleep, and inheriting mutations affecting the potassium current Shaker results in flies that sleep less and have a shorter lifespan. However, whether the link between short sleep and reduced longevity exists also in wild-type flies is unknown. Similarly, it is unknown whether such a link depends on sleep amount per se, rather than on other factors such as waking activity. Also, sleep quality has been shown to decrease in old flies, but it remains unclear whether aging-related sleep fragmentation is a generalized phenomenon.</p> <p>Results</p> <p>We compared 3 short sleeping mutant lines (<it>Hk</it><sup>1</sup>, <it>Hk</it><sup><it>Y </it></sup>and <it>Hk</it><sup>2</sup>) carrying a mutation in Hyperkinetic, which codes for the beta subunit of the Shaker channel, to wild-type siblings throughout their entire lifespan (all flies kept at 20°C). <it>Hk</it><sup>1 </sup>and <it>Hk</it><sup><it>Y </it></sup>mutants were short sleeping relative to wild-type controls from day 3 after eclosure, and <it>Hk</it><sup>2 </sup>flies became short sleepers about two weeks later. All 3 <it>Hk </it>mutant lines had reduced lifespan relative to wild-type flies. Total sleep time showed a trend to increase in all lines with age, but the effect was most pronounced in <it>Hk</it><sup>1 </sup>and <it>Hk</it><sup><it>Y </it></sup>flies. In both mutant and wild-type lines sleep quality did not decay with age, but the strong preference for sleep at night declined starting in "middle age". Using Cox regression analysis we found that in <it>Hk</it><sup>1 </sup>and <it>Hk</it><sup><it>Y </it></sup>mutants and their control lines there was a negative relationship between total sleep amount during the first 2 and 4 weeks of age and hazard (individual risk of death), while no association was found in <it>Hk</it><sup>2 </sup>flies and their wild-type controls. <it>Hk</it><sup>1 </sup>and <it>Hk</it><sup><it>Y </it></sup>mutants and their control lines also showed an association between total daily wake activity over the first 2 and 4 weeks of age and hazard. However, when both sleep duration and wake activity were used in the same regression, the effects of activity were much reduced, while most of the sleep effects remained significant. Finally, <it>Hk</it><sup>1 </sup>flies and wild-type siblings were also tested at 25°C, and results were similar to those at 20°C. Namely, <it>Hk</it><sup>1 </sup>mutants were short sleeping, hyperactive, and short lived relative to controls, and sleep quality in both groups did not decrease with age.</p> <p>Conclusions</p> <p>Different <it>Hk </it>mutations affect the sleep phenotype, and do so in an age-dependent manner. In 4 of the 6 lines tested sleep associates significantly with lifespan variation even after any effect of activity is removed, but activity does not associate significantly with lifespan after the effects of sleep are removed. Thus, in addition to environmental factors and genetic background, sleep may also affect longevity. Sleep quality does not necessarily decay as flies age, suggesting that aging-related sleep fragmentation may also depend on many factors, including genetic background and rearing conditions.</p

    Direct Detection of Electroweak-Interacting Dark Matter

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    Assuming that the lightest neutral component in an SU(2)L gauge multiplet is the main ingredient of dark matter in the universe, we calculate the elastic scattering cross section of the dark matter with nucleon, which is an important quantity for the direct detection experiments. When the dark matter is a real scalar or a Majorana fermion which has only electroweak gauge interactions, the scattering with quarks and gluon are induced through one- and two-loop quantum processes, respectively, and both of them give rise to comparable contributions to the elastic scattering cross section. We evaluate all of the contributions at the leading order and find that there is an accidental cancellation among them. As a result, the spin-independent cross section is found to be O(10^-(46-48)) cm^2, which is far below the current experimental bounds.Comment: 19 pages, 7 figures, published versio
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