Deletion of macro domain containing 2(MACRO D2) associated with transient hydrops fetalis

Cilingir, I. Uzun (Trakya Author) Sayin, Niyazi Cenk (Trakya Author) Gurkan, H.(Trakya Author) Ciftdemir, N. A. (Trakya Author) Atli, E. (Trakya Author) Inan, C. (Trakya Author) Erzincan, S. (Trakya Author) Sutcu, H. (Trakya Author) Vatansever, U. (Trakya Author) Varol, Fusun (Trakya Author)Macro Domain Containing 2 (MACRO D2) gene is a gene from macro family which is highly expressed in the ventriculer zone of the brain during embryonic development. Association between Autism spectrum disorders and MACRO D2 gene polymorphisms has been reported before [1] . Deletion in MACRO D2 gene has also been associated with Kabuki Syndrome which is a well described congential anomaly syndrome [2]