V. P. Omelchenko in the history of professional education Chelyabinsk region

В статье на основе фактического материала представлена биография крупного организатора и педагога профессионального образования, начальника областного управления професссионально-технического образования Челябинской области В. П. Омельченко.On the basis of rich factual material presented biography of a great organizer and teacher of vocational education, head of the regional professional education Chelyabinsk Region Omelchenko

Taming the tiger by the tail: modulation of DNA damage responses by telomeres

Telomeres are by definition stable and inert chromosome ends, whereas internal chromosome breaks are potent stimulators of the DNA damage response (DDR). Telomeres do not, as might be expected, exclude DDR proteins from chromosome ends but instead engage with many DDR proteins. However, the most powerful DDRs, those that might induce chromosome fusion or cell-cycle arrest, are inhibited at telomeres. In budding yeast, many DDR proteins that accumulate most rapidly at double strand breaks (DSBs), have important functions in physiological telomere maintenance, whereas DDR proteins that arrive later tend to have less important functions. Considerable diversity in telomere structure has evolved in different organisms and, perhaps reflecting this diversity, different DDR proteins seem to have distinct roles in telomere physiology in different organisms. Drawing principally on studies in simple model organisms such as budding yeast, in which many fundamental aspects of the DDR and telomere biology have been established; current views on how telomeres harness aspects of DDR pathways to maintain telomere stability and permit cell-cycle division are discussed

Differentiation polynomials in local fractional analysis based on d-operator

It is shown that in local fractional analysis there are rather simple integrable fractional-order functions, a certain order base primitive of which equals zero

The generalized G-operator of complex orders of real variable

The author introduces the local differentiation and integration G-operator of a complex order real variable which is the generalization of d-operator of real orders in the case of infinite number of local operators for which the conformity principle is fulfilled. The paper considers its several properties and special cases

Work and everyday military of evacuated professionals in the South Ural (1941–1945)

В статье на основе фактического материала раскрывается особенность жизни в советском тылу эвакуированных специалистов, прибывших на Южной Урал вместе с промышленными предприятиями из временно оккупированных районов СССР. Рассматриваются их трудовая деятельность и повседневные практики выживания.On the base of factual evidence the article deals with the specific nature of life of professional employees in soviet back areas who came to the South Ural with factories from temporary occupied area in the USSR. The author considers their working practice and daily survival techniques

Evaluation of innovative development of the Russian Federation based on the 2020 vision and strategy indicators

The main indicators of the innovative development of the Russian Federation are considered on the basis of the data presented in two regulatory documents developed in 2008 and 2011. The indicators cover a wide range of areas of socio-economic development, and their values should be achieved by 2020. However, the targets of macroeconomic indicators laid down in the documents at the current moment of time are seen to be overestimated. The analysis of the main achievements in the field of innovative development of our country over a ten-year period is carried out. For the analysis, a set of statistical data published in various sources was used, as well as the values of target macroeconomic indicators published in the concept and strategy. Based on the assessment of indicators and their deviations, an analysis is made of the success of the innovative development of Russia in various areas - from the development of the high-tech sector to the publication activity of the authors. Based on the results obtained, it was concluded that these or those target values of macroeconomic indicators have been achieved at the current time and an assumption about achieving these values by 2020. In addition, based on the analysis, it was determined which of the three options for innovative development our country is implementing at the present stage. The main reasons that prevented the experts and the Government of the Russian Federation from reaching the main target indicators of the concept and strategy and transferring our country to “innovative tracks” are summarized