1 research outputs found
Heterodimers Made of Upconversion Nanoparticles and Metal–Organic Frameworks
Creating nanoparticle dimers has
attracted extensive interest.
However, it still remains a great challenge to synthesize heterodimers
with asymmetric compositions and synergistically enhanced functions.
In this work, we report the synthesis of high quality heterodimers
composed of porphyrinic nanoscale metal–organic frameworks
(nMOF) and lanthanide-doped upconversion nanoparticles (UCNPs). Due
to the dual optical properties inherited from individual nanoparticles
and their interactions, absorption of low energy photons by the UCNPs
is followed by energy transfer to the nMOFs, which then undergo activation
of porphyrins to generate singlet oxygen. Furthermore, the strategy
enables the synthesis of heterodimers with tunable UCNP size and dual
NIR light harvesting functionality. We demonstrated that the hybrid
architectures represent a promising platform to combine NIR-induced
photodynamic therapy and chemotherapy for efficient cancer treatment.
We believe that such heterodimers are capable of expanding their potential
for applications in solar cells, photocatalysis, and nanomedicine