325 research outputs found
An undulation theory for condensation in open end slit pores: Critical hysteresis temperature & critical hysteresis pore size
A new theory of condensation in an open end slit pore, based on the concept of temperature dependent undulation, at the interface separating the adsorbed phase and the gas-like region, is presented. The theory, describes, for the first time, the microscopic origin of the critical hysteresis temperature and the critical hysteresis pore size, properties which are not accessible to any classical theories
GW26-e2102 Gut microbiota alter cholesterol metabolism and regulate NPC1L1 by inducing the expression of Cyp7a1
Skill Assessment Using Behavior Data in Virtual World
ABSTRACT Highly interactive game-like virtual environment has gained increasing spotlight in academic and educational researches. Besides being an efficient and engaging educational tool, virtual environment also collects a lot of behavior data which can be used with Educational Data Mining (EDM) techniques to assess students' learning competencies. In this paper, we propose an assessment system that seamlessly integrates EDM techniques with functionality and affordance of a virtual environment to assess students' learning competency through analyzing their behavioral data and patterns. The virtual environment can record not only students' learning outcome, but also their detailed learning process information, which has the potential to depict the full set of students' learning activity. We also propose a set of metrics which can be used for judging students' Self-Directed Learning skills and how these metrics can be evaluated computationally by capturing students' behavioral data in a virtual environment. The field study, which is conducted in Xinmin Secondary School in Singapore, preliminarily illustrates the effectiveness of our approach
SPOP suppresses tumorigenesis by regulating hedgehog/Gli2 signaling pathway in gastric cancer
Fast Super-Resolution Imaging with Ultra-High Labeling Density Achieved by Joint Tagging Super-Resolution Optical Fluctuation Imaging (JT-SOFI)
Previous stochastic localization-based super-resolution techniques are
largely limited by the labeling density and the fidelity to the morphology of
specimen. We report on an optical super-resolution imaging scheme implementing
joint tagging using multiple fluorescent blinking dyes associated with
super-resolution optical fluctuation imaging (JT-SOFI), achieving ultra-high
labeling density super-resolution imaging. To demonstrate the feasibility of
JT-SOFI, quantum dots with different emission spectra were jointly labeled to
the tubulin in COS7 cells, creating ultra-high density labeling. After
analyzing and combining the fluorescence intermittency images emanating from
spectrally resolved quantum dots, the microtubule networks are capable of being
investigated with high fidelity and remarkably enhanced contrast at
sub-diffraction resolution. The spectral separation also significantly
decreased the frame number required for SOFI, enabling fast super-resolution
microscopy through simultaneous data acquisition. As the joint-tagging scheme
can decrease the labeling density in each spectral channel, we can faithfully
reflect the continuous microtubule structure with high resolution through
collection of only 100 frames per channel. The improved continuity of the
microtubule structure is quantitatively validated with image skeletonization,
thus demonstrating the advantage of JT-SOFI over other localization-based
super-resolution methods.Comment: 19 pages, 4 figures, with S
A molecular simulation study of adsorption and desorption in closed end slit pores: Is there a hysteresis loop?
This paper reports detailed simulations of adsorption and desorption of argon in closed end slit pores with the aim of investigating the existence of hysteresis. The classical thermodynamic approach implies that there should be no hysteresis in a closed end pore because it assumes that the condensed phase is identical to a uniform bulk liquid and that the interface between the gas-like region and the dense adsorbate region is the same when the pore fills as when it empties. Our simulations show that hysteresis is possible and we support this assertion with evidence from a critical analysis of the classical equation. Our extensive results show that hysteresis can occur in closed end pores because of the continuous structuring of the adsorbed phase induced by the combined effects of the solid-fluid interaction and the fluid-fluid interaction
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