1 research outputs found
Cu-Mediated Stereoselective [4+2] Annulation between <i>N</i>‑Hydroxybenzimidoyl Cyanide and Norbornene
A Cu-mediated stereoselective [4+2]
annulation between <i>N</i>-hydroxybenzimidoyl cyanides
and norbornene (NBE) has been
developed for the synthesis of 4<i>H</i>-1,2-oxazin-4-ones.
The reaction proceeds through sequentially forming C–O/C–C
bonds. The advantage of this reaction includes high stereoselectivity,
excellent yields, as well as simple and mild reaction conditions.
A total of 26 examples are presented along with some control experiments