Supervivencia en pacientes con COVID-19 ingresados en UCI en un hospital de tercer nivel de Lambayeque, Perú.

Introduction: COVID-19, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has reached pandemic proportions worldwide, persisting over time. In this context, this study aims to analyze the factors associated with mortality in hospitalized patients with COVID-19 in a third-level hospital in the Lambayeque region. Material and metodo: A retrospective cohort study was conducted on patients diagnosed with COVID-19, hospitalized at the National Hospital Almanzor Aguinaga Asenjo (HNAAA) during the months of March to September 2020. Results: Forty patients admitted to the Intensive Care Unit (ICU) were examined, of whom twenty-two required mechanical ventilation (MV). Overall mortality in the ICU was 68.7%, while mortality among patients who required mechanical ventilation was 91.6%. A statistical association was found between death and vital signs on admission to the ICU, as well as with the waiting time for admission. The probability of survival at 2 and 7 days was 90.1% and 45.5%, respectively. Conclusions: In this cohort, a mortality rate of 68.7% was observed in the ICU, with a survival rate of 45.5% at 7 days and less than 10% at 18 days. No associations were found between survival and any of the variables of interest.Introducción: La COVID-19, causada por el Coronavirus 2 del Síndrome Respiratorio Agudo Severo (SARS-CoV-2), ha alcanzado proporciones pandémicas a nivel mundial, prolongándose en el tiempo. En este contexto, el presente estudio tiene como objetivo analizar los factores asociados a la mortalidad en pacientes hospitalizados por COVID-19 en un hospital de tercer nivel de la región Lambayeque. Material y método: Se realizó un estudio de cohorte retrospectivo de los pacientes con diagnóstico de COVID-19, hospitalizados en el Hospital Nacional Almanzor Aguinaga Asenjo (HNAAA) durante los meses de marzo a septiembre del 2020.  Resultados: Se examinaron cuarenta pacientes que ingresaron en la Unidad de Cuidados Intensivos (UCI), de los cuales veintidós necesitaron ventilación mecánica (VM). La mortalidad general en la UCI fue del 68.7%, mientras que la mortalidad entre los pacientes que necesitaron ventilación mecánica fue del 91.6%. Se encontró una asociación estadística entre el fallecimiento y los signos vitales al ingreso en la UCI, así como con el tiempo de espera para el ingreso. La probabilidad de supervivencia a 2 y 7 días fue del 90.1% y del 45.5%, respectivamente. Conclusiones: En esta cohorte, se observó una tasa de mortalidad del 68.7% en UCI, con una tasa de supervivencia del 45.5% a los 7 días y menos del 10% a los 18 días. No se encontró asociaciones entre la supervivencia y ninguna de las variables de interés

Prevalence and Associated Factors of Depression, Anxiety, and Stress in University Students in Paraguay during the COVID-19 Pandemic

We aimed to determine the prevalence of depression, anxiety, and stress in university students in Paraguay during the COVID-19 pandemic. A cross-sectional study was conducted among 293 students from four universities in Paraguay in 2021. The DASS-21 mental health scale was used to measure the outcomes (depression, anxiety, and stress) and evaluate their association with socio-educational variables. A total of 77.1% of the participants were women and 136 (46.4%) were between 21 and 25 years old. The prevalence of depression, anxiety, and stress was 74.7%, 87.4%, and 57%, respectively. We found that being a woman and studying at a public university was positively associated with depression, anxiety, and stress. Receiving COVID-19 training increases the prevalence of mental health problems. In conclusion, high levels of anxiety, depression, and stress were found in university students during the COVID-19 pandemic. Being a woman, studying at a public university, and receiving training on COVID-19 were factors associated with a higher prevalence of presenting all the mental health problems evaluated. Furthermore, students aged 31 and over had a higher prevalence of depression and stress

Depression, anxiety, and stress in medical students in Peru: a cross-sectional study

ObjectiveTo determine the prevalence and factors associated with depressive, anxious, and stress symptoms in medical students in Peru, during the second pandemic wave of COVID-19.MethodsWe conducted an analytical cross-sectional study in 405 medical students from a university in northern Peru. The DASS-21 instrument was used to evaluate mental health outcomes (depression, anxiety, and stress), and to investigate their association with socio-educational characteristics.ResultsWe found a prevalence of depressive, anxious, and stress symptoms of 71.6% (95% CI: 66.94–75.95), 71.9% (95% CI: 67.2–76.2), and 62.7% (95% CI: 57.8–67.4); respectively. Students with eating behavior disorders had a higher prevalence of depressive symptoms (PR: 1.35), anxious symptoms (PR: 1.27), and stress symptoms (PR: 1.31). The prevalence of depressive symptoms (PR: 1.57), anxious symptoms (PR: 1.27), and stress symptoms (PR: 1.24) increased in students who did not report regular physical activity. In addition, having almost always academic exhaustion increased the prevalence of depressive symptoms (PR: 1.46), stress symptoms (PR: 1.72). On the contrary, the prevalence of depressive symptoms (PR: 0.79), anxious symptoms (PR: 0.73) and stress symptoms (PR: 0.82) decreased in male students. Students who reported sleeping 8 or more hours daily had a lower prevalence of stress symptoms (PR: 0.82).ConclusionSymptoms of depression and anxiety occurred in 7 out of 10 students, and stress in 6 out of 10. Among the factors associated with the presence of anxiety, depression, and stress were eating behavior disorder and not regularly exercising. Periodic evaluations of mental symptomatology are required and counseling should be promoted in medical schools

Factors associated with mortality in patients hospitalized for COVID-19 admitted to a tertiary hospital in Lambayeque, Peru, during the first wave of the pandemic.

IntroductionCOVID-19 caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread worldwide, becoming a long-term pandemic.ObjectivesTo analyze the factors associated with mortality in patients hospitalized for COVID-19 in a tertiary hospital in the Lambayeque region of Peru.MethodsA retrospective cohort study of patients with a diagnosis of COVID-19, hospitalized in a hospital in northern Peru, was conducted from March to September 2020.ResultsOf the 297 patients studied, 69% were women, the mean age was 63.99 years (SD = ±15.33 years). Hypertension was the most frequent comorbidity (36.67%), followed by diabetes mellitus (24.67%) and obesity (8.33%). The probability of survival at 3 days of ICU stay was 65.3%, at 7 days 24.2%, and 0% on day 14. Risk factors associated with mortality in patients hospitalized for COVID-19 are age, male sex, tachypnea, low systolic blood pressure, low peripheral oxygen saturation, impaired renal function, elevated IL-6 and elevated D-dimer.ConclusionsMortality in hospitalized patients with COVID-19 was 51.18 per 100 persons, Mortality was found to be associated with hypertension, type of infiltrating, and sepsis