Benefit-cost ratios for the different strategies.

*<p>The negative value is a result of the empirical treatment strategy being both less expensive and more effective than the <i>no –antibiotic</i>- treatment baseline</p

Costs (USD).

a<p>Cost of doxycycline (100 mg) 14 capsules in Thailand</p>b<p>Cost as of 2004 of lateral flow, MCAT, latex test.</p>c<p>Treatment of side effect symptoms such as antiemetic drug or antihistamine for rash.</p><p>With work loss, 1 day at minimum earning (5.25 USD) assumed.</p><p>There is no additional cost to patients not receiving antibiotics or to being cured.</p>d<p>Estimate of hospital costs, including intravenous antibiotics, other treatment.</p

Values and sources of inputs used in the decision model.

<p>Values and sources of inputs used in the decision model.</p

Test performance using acute sera [10],[14].

<p>Test performance using acute sera <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000610#pntd.0000610-Kemapunmanus1" target="_blank">[10]</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000610#pntd.0000610-Arimitsu1" target="_blank">[14]</a>.</p

Costs, clinical outcomes and antibiotic prescription at various prevalence rates and for patients receiving no treatment, empirical treatment, diagnosis using the latex test and diagnosis with a test with 95% sensitivity and specificity.

<p>Costs, clinical outcomes and antibiotic prescription at various prevalence rates and for patients receiving no treatment, empirical treatment, diagnosis using the latex test and diagnosis with a test with 95% sensitivity and specificity.</p