Metastatic lymph node in a 51-year-old woman.

<p>A: T2*WI, B: T2* map, with black representing the lowest T2* value and red representing the highest T2* value. C: corresponding histology image. The metastatic lymph node displays higher signal intensity than background on the T2* map.</p

Receiver operating characteristics curves for T2* value in metastatic and benign axillary lymph nodes discrimination.

<p>Receiver operating characteristics curves for T2* value in metastatic and benign axillary lymph nodes discrimination.</p

Spindle-Shaped Apatite La–Silicate Mesocrystals Grown via a Multistep Nucleation and Growth Mechanism, A New Strategy for Preparing Ordered Nanoscale Superstructures

A precise control over the growth of mesocrystals composed of crystallographically aligned nanocrystals is necessary to exploit their collective properties for potential applications. Here, we describe a successful preparation of spindle-shaped apatite La–silicate (ap-LSO) mesocrystals with an ordered arrangement of elongated nanocrystals along <i>c</i>-axis through a solvothermal process, as revealed by X-ray diffraction, scanning electron microscopy, transmission electron microscopy–selected area electron diffraction, and high-resolution transmission electron microscopy. It has been shown that a multistep nucleation and growth mechanism would be responsible for the formation of the mesocrystals. This novel mesocrystal formation mechanism breaks through the classical crystallization norm and opens a new way to constructing mesocrystals with nanoscale superstructures

A plot of the T2* values of each metastatic and benign axillary lymph nodes.

<p>The horizontal axis indicates the lymph node number, and the vertical axis indicates the T2* values. Black rhombus represents metastatic nodes and red squares represent benign nodes, respectively.</p

Representative T1-weighted image (T1WI), T2-weighted image (T2WI), T2*-weighted image (T2*WI) and susceptibility-weighted imaging (SWI) of a 42 year-old patient with splenic siderotic nodules.

<p>SWI shows more siderotic nodules than T1WI, T2WI or T2*WI.</p

Circular map of the CnmeGV genome.

<p>ORFs and transcription direction are indicated as arrows. Core genes were indicated by red arrows, genes present in other baculovirus were indicated by pink arrows, unique genes were indicated by blue arrows and <i>hrs</i> were indicated by yellow squares. The innermost circle shows GC skew, which indicates possible locations of the DNA leading strand, lagging strand, replication origin, and replication terminal during DNA replication. Below average GC skew is light orange and above average dark orange. The next innermost circle is a GC plot, with light green representing below average GC content, and dark green indicating above average GC content.</p

Structural domain and phylogenetic analysis of ORF21.

<p><b>(A)</b> The structural organization of ORF21 protein. It contains a transmembrane helix domain (TD) and two carbohydrate-binding modules family 14 (CBM_14A and CBM_14B). <b>(B)</b> Transmembrane helix region was detected by the TMHAMM V2.0 program. <b>(C)</b>The NJ tree was inferred using the conserved amino-terminal region alignment of ORF21 gene for 13 baculoviruses. The postulated horizontal gene transfer (HGT) events are highlighted for CnmeGV.</p

A plot of the number of siderotic nodules detected by MRI in each patient.

<p>The horizontal axis indicates the patient number, and the vertical axis indicates the number of siderotic nodules. Black rhombus, red squares, yellow triangles and blue star represent T1-weighted imaging, T2-weighted imaging, T2*-weighted imaging, and susceptibility-weighted imaging, respectively.</p

Syntenic map of CnmeGV and other baculovirus genomes.

<p>The illustration shows the comparison of gene colinearity based on genome physical positions and protein similarities among 17 GVs and AcMNPV. Each genome is represented by a grey line where nucleotide positions are indicated (kb). Red stripes connecting the genomes indicate syntenic regions in the same strand, whereas blue stripes indicate syntenic regions in opposite strands (inversions). Color intensity is proportional to %identity (darker is more conserved).</p

All species from the genus <i>Betabaculovirus</i> completely sequenced to date^*.

<p>All species from the genus <i>Betabaculovirus</i> completely sequenced to date^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0147882#t001fn001" target="_blank">*</a>}.</p