Linear Driving Force Model for Adsorption onto Activated Carbon Monolith

A mathematical model on carbon coated   monolith   using the  linear driving force model is develop. The computer program is writted in MATLAB and simulation using data from [4] for cell density 200 cpsi was used to studies the effect of different variables on breakthrough profiles.  The result showed that the breakthrough curve of the monolith is very sharp. Because of its an open structure and  lower pressure drop,   monolith  is an attractive alternative internals for separation.Keywords:  Adsorption, modeling, simulation, carbon coated monolith, breakthroug

Calcium-dependent and phosphorylation-stimulated proteolysis of lipocortin I by an endogenous A431 cell membrane protease

Journal of Biological Chemistry2643521160-21166JBCH

Bilineal T lymphoblastic and myeloid blast transformation in chronic myeloid leukemia with TP53 mutation-an uncommon presentation in adults

10.3747/co.21.1660Current Oncology211e147-e150CUON

Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition

10.1182/blood-2013-07-511907Blood123213316-332

Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium

10.1016/j.yjmcc.2008.04.007Journal of Molecular and Cellular Cardiology45170-80JMCD

Structural and functional 3D mapping of skin tumours with non-invasive multispectral optoacoustic tomography.

BACKGROUND: Recent advances in technology have enabled the development of various non-invasive skin imaging tools to aid real-time diagnosis of both benign and malignant skin tumours, minimizing the need for invasive skin biopsy. Multispectral optoacoustic tomography (MSOT) is a recently developed non-invasive imaging tool, which offers the unique capacity for high resolution three dimensional (3D) optical mapping of tissue by further delivering highly specific optical contrast from a depth of several millimetres to centimetres in living tissues. MSOT enables volumetric, spectroscopic differentiation of tissue, both in vivo and in real time, with and without the application of biomarker-specific probes, and is further able of providing spatial maps of skin chromophores, as well as underlying blood vasculature. METHODS: Three patients with suspicious skin tumours consented to have their lesions imaged with MSOT prior to excision. The histological findings and measurements were compared. RESULTS: We demonstrated the first in vivo clinical use of MSOT for 3D reconstruction of skin tumours in three patients with good histological correlation. CONCLUSION: Our findings confirm the potential benefit of the new imaging method in guiding surgical intervention to achieve a more precise excision with better clearance and lower relapse rates. It can also potentially help to shorten the duration of Mohs' micrographic surgery. Further large-scale studies are necessary to ensure correlation between MSOT and histology