27,952 research outputs found

    Improving Effective Surgical Delivery in Humanitarian Disasters: Lessons from Haiti

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    Kathryn Chu and colleagues describe the experiences of Médecins sans Frontières after the 2010 Haiti earthquake, and discuss how to improve delivery of surgery in humanitarian disasters

    Antiarrhythmic effect of the calcium antagonist tiapamil (ro 11–1781) by intravenous administration in patients with coronary heart disease

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    Twenty coronary patients with a median age of 76 years were treated in the coronary care unit with tiapamil, a new Ca2+ antagonist, by intravenous infusion (until December, 1979, the generic name was dimeditiapramine). The following arrhythmias were identified: atrial fibrillation with ventricular rate greater than 95 beats/min (5 patients); supraventricular premature complexes (SVPC) (4 patients); and ventricular premature complexes (VPC), Lown grades 2-4 (15 patients). Electrocardiograms and hemodynamic parameters were continuously monitored prior to, during, and after the therapy. In patients with atrial fibrillation, sinus rhythm was not restored, but tiapamil decreased the ventricular rate by 54%. In patients with VPC, the median frequency of VPC decreased from 310.5 before tiapamil to 32.5 beats/h at the fourth hour of therapy (p less than 0.01). The median ectopic/sinus beat ratio decreased from 0.083 (pretreatment) to 0.008 at the fourth hour of infusion (p less than 0.10). In one of the patient with an insufficient decrease in the number of VPC, the VPOC changed from class 4a (pretreatment) to class 2 (during the therapy), returning to class 4a after the infusion was stopped. Tiapamil reduced the median systolic and diastolic blood pressures by 8.3 and 7.1%, respectively (p less than 0.05), the third hour. Hypotension and bradycardia were observed in 5/20 patients. The results show that tiapamil is effective against both supraventricular and ventricular arrhythmias, and thus its spectrum of action differs from that of other calcium antagonists

    Limit cycles of effective theories

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    A simple example is used to show that renormalization group limit cycles of effective quantum theories can be studied in a new way. The method is based on the similarity renormalization group procedure for Hamiltonians. The example contains a logarithmic ultraviolet divergence that is generated by both real and imaginary parts of the Hamiltonian matrix elements. Discussion of the example includes a connection between asymptotic freedom with one scale of bound states and the limit cycle with an entire hierarchy of bound states.Comment: 8 pages, 3 figures, revtex

    Scalable Parallel Numerical CSP Solver

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    We present a parallel solver for numerical constraint satisfaction problems (NCSPs) that can scale on a number of cores. Our proposed method runs worker solvers on the available cores and simultaneously the workers cooperate for the search space distribution and balancing. In the experiments, we attained up to 119-fold speedup using 256 cores of a parallel computer.Comment: The final publication is available at Springe

    On the Non-invasive Measurement of the Intrinsic Quantum Hall Effect

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    With a model calculation, we demonstrate that a non-invasive measurement of intrinsic quantum Hall effect defined by the local chemical potential in a ballistic quantum wire can be achieved with the aid of a pair of voltage leads which are separated by potential barriers from the wire. B\"uttiker's formula is used to determine the chemical potential being measured and is shown to reduce exactly to the local chemical potential in the limit of strong potential confinement in the voltage leads. Conditions for quantisation of Hall resistance and measuring local chemical potential are given.Comment: 16 pages LaTex, 2 post-script figures available on reques

    High-Accuracy Self-Calibration for Smart, Optical Orbiting Payloads Integrated with Attitude and Position Determination.

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    A high-accuracy space smart payload integrated with attitude and position (SSPIAP) is a new type of optical remote sensor that can autonomously complete image positioning. Inner orientation parameters (IOPs) are a prerequisite for image position determination of an SSPIAP. The calibration of IOPs significantly influences the precision of image position determination of SSPIAPs. IOPs can be precisely measured and calibrated in a laboratory. However, they may drift to a significant degree because of vibrations during complicated launches and on-orbit functioning. Therefore, laboratory calibration methods are not suitable for on-orbit functioning. We propose an on-orbit self-calibration method for SSPIAPs. Our method is based on an auto-collimating dichroic filter combined with a micro-electro-mechanical system (MEMS) point-source focal plane. A MEMS procedure is used to manufacture a light transceiver focal plane, which integrates with point light sources and a complementary metal oxide semiconductor (CMOS) sensor. A dichroic filter is used to fabricate an auto-collimation light reflection element. The dichroic filter and the MEMS point light sources focal plane are integrated into an SSPIAP so it can perform integrated self-calibration. Experiments show that our method can achieve micrometer-level precision, which is good enough to complete real-time calibration without temporal or spatial limitations

    Commodity procurement risk management with futures contracts: a dynamic stack-and-roll approach

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    Procuring material from commodity spot markets can flexibly fulfil a forward production demand, but increase the risk of high procurement cost due to spot price volatility. In this paper, a dynamic stack-and-roll hedging approach using futures contracts is proposed. The approach aims at mitigating the procurement cost risk and optimising the terminal revenue received from the procurement and hedging activities. It separates the procurement planning horizon into multiple stages, along with varying hedging positions in the nearby futures contracts. Hedging positions are adjusted in response to commodity price behaviour and contemporary perceived information about forward production demand. Guided by the mean-variance criteria over the terminal revenue, dynamic programming is applied to derive a closed-form solution for optimal hedging positions in a discrete-time Markovian setting. Numerical experiments are carried out to assess the proposed approach with explicit solution in a realistic stochastic environment. The price processes are modelled by a fractal nonlinear regression model using real price data of China’s commodity market, while demand information process is modelled by Bayesian formula. The results show that the proposed approach outperforms naive hedging strategy, and effectively mitigates the procurement cost risk.postprin
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