Search for D to phi l nu and measurement of the branching fraction for D to phi pi

Using a data sample of integrated luminosity of about 33 pb$^{-1}$ collected around 3.773 GeV with the BESII detector at the BEPC collider, the semileptonic decays $D^+ \to \phi e ^+\nu_e$, $D^+ \to \phi \mu^+\nu_\mu$ and the hadronic decay $D^+ \to \phi \pi^+$ are studied. The upper limits of the branching fractions are set to be $BF(D^+ \to \phi e ^+\nu_e) <$ 2.01% and $BF(D^+ \to \phi \mu^+ \nu_\mu) <$ 2.04% at the 90% confidence level. The ratio of the branching fractions for $D^+ \to \phi \pi^+$ relative to $D^+ \to K^-\pi^+\pi^+$ is measured to be $0.057 \pm 0.011 \pm 0.003$. In addition, the branching fraction for $D^+ \to \phi \pi^+$ is obtained to be $(5.2 \pm 1.0 \pm 0.4) \times 10^{-3}$.Comment: 6 pages, 5 figures, to be published in Eur.Phys.J.

Measurements of branching fractions for inclusive K0~/K0 and K*(892)+- decays of neutral and charged D mesons

Using the data sample of about 33 pb-1 collected at and around 3.773 GeV with the BES-II detector at the BEPC collider, we have studied inclusive K0~/K0 and K*(892)+- decays of D0 and D+ mesons. The branching fractions for the inclusive K0~/K0 and K*(892)- decays are measured to be BF(D0 to K0~/K0 X)=(47.6+-4.8+-3.0)%, BF(D+ to K0~/K0 X)=(60.5+-5.5+-3.3)%, BF(D0 to K*- X)=(15.3+- 8.3+- 1.9)% and BF(D+ to K*- X)=(5.7+- 5.2+- 0.7)%. The upper limits of the branching fractions for the inclusive K*(892)+ decays are set to be BF(D0 to K*+ X)<3.6% and BF(D+ to K*+ X) <20.3% at 90% confidence level

Direct Measurements of the Branching Fractions for Inclusive K±K^\pm and Inclusive Semileptonic Decays of D+D^+ and D0D^0 Mesons

With singly-tagged $\bar D$ samples selected from the data collected at and around 3.773 GeV with the BESII detector at the BEPC collider, we have measured the branching fractions for the inclusive $K^\pm$ decays of $D^+$ and $D^0$ mesons, which are $BF(D^+\to K^-X) = (24.7 \pm 1.3 \pm 1.2)$, $BF(D^+\to K^+X) = (6.1 \pm 0.9 \pm 0.4)$, $BF(D^0\to K^-X) = (57.8 \pm 1.6 \pm 3.2)$ and $BF(D^0\to K^+X) = (3.5 \pm 0.7 \pm 0.3)$, respectively. We have also measured the branching fractions for the inclusive semileptonic decays of $D^+$ and $D^0$ mesons to be $BF(D^+ \to e^+ X)=(15.2 \pm 0.9 \pm 0.8)$ and $BF(D^0 \to e^+ X) =(6.3 \pm 0.7 \pm 0.4)$. These yield the ratio of their partial widths to be $\Gamma(D^+ \to e^+X)/\Gamma(D^0 \to e^+X)=0.95 \pm 0.12 \pm 0.07$.Comment: 6 pages, 5 figure

A Unified Approach to the Classical Statistical Analysis of Small Signals

We give a classical confidence belt construction which unifies the treatment of upper confidence limits for null results and two-sided confidence intervals for non-null results. The unified treatment solves a problem (apparently not previously recognized) that the choice of upper limit or two-sided intervals leads to intervals which are not confidence intervals if the choice is based on the data. We apply the construction to two related problems which have recently been a battle-ground between classical and Bayesian statistics: Poisson processes with background, and Gaussian errors with a bounded physical region. In contrast with the usual classical construction for upper limits, our construction avoids unphysical confidence intervals. In contrast with some popular Bayesian intervals, our intervals eliminate conservatism (frequentist coverage greater than the stated confidence) in the Gaussian case and reduce it to a level dictated by discreteness in the Poisson case. We generalize the method in order to apply it to analysis of experiments searching for neutrino oscillations. We show that this technique both gives correct coverage and is powerful, while other classical techniques that have been used by neutrino oscillation search experiments fail one or both of these criteria.Comment: 40 pages, 15 figures. Changes 15-Dec-99 to agree more closely with published version. A few small changes, plus the two substantive changes we made in proof back in 1998: 1) The definition of "sensitivity" in Sec. V(C). It was inconsistent with our actual definition in Sec. VI. 2) "Note added in proof" at end of the Conclusio

Measurement of \psip Radiative Decays

Using 14 million psi(2S) events accumulated at the BESII detector, we report first measurements of branching fractions or upper limits for psi(2S) decays into gamma ppbar, gamma 2(pi^+pi^-), gamma K_s K^-pi^++c.c., gamma K^+ K^- pi^+pi^-, gamma K^{*0} K^- pi^+ +c.c., gamma K^{*0}\bar K^{*0}, gamma pi^+pi^- p pbar, gamma 2(K^+K^-), gamma 3(pi^+pi^-), and gamma 2(pi^+pi^-)K^+K^- with the invariant mass of hadrons below 2.9GeV/c^2. We also report branching fractions of psi(2S) decays into 2(pi^+pi^-) pi^0, omega pi^+pi^-, omega f_2(1270), b_1^\pm pi^\mp, and pi^0 2(pi^+pi^-) K^+K^-.Comment: 5 pages, 4 figure

Measurement of the branching fractions of psi(2S) -> 3(pi+pi-) and J/psi -> 2(pi+pi-)

Using data samples collected at sqrt(s) = 3.686GeV and 3.650GeV by the BESII detector at the BEPC, the branching fraction of psi(2S) -> 3(pi+pi-) is measured to be [4.83 +- 0.38(stat) +- 0.69(syst)] x 10^-4, and the relative branching fraction of J/psi -> 2(pi+pi-) to that of J/psi -> mu+mu- is measured to be [5.86 +- 0.19(stat) +- 0.39(syst)]% via psi(2S) -> (pi+pi-)J/psi, J/psi -> 2(pi+pi-). The electromagnetic form factor of 3(pi+pi-) is determined to be 0.21 +- 0.02 and 0.20 +- 0.01 at sqrt(s) = 3.686GeV and 3.650GeV, respectively.Comment: 17pages, 7 figures, submitted to Phys. Rev.

Peg-interferon lambda treatment induces robust innate and adaptive immunity in chronic hepatitis B patients

IFN-lambda (IFNλ) is a member of the type III IFN family and is reported to possess anti-pathogen, anti-cancer, and immunomodulatory properties; however, there are limited data regarding its impact on host immune responses in vivo. We performed longitudinal and comprehensive immunosurveillance to assess the ability of pegylated (peg)-IFNλ to augment antiviral host immunity as part of a clinical trial assessing the efficacy of peg-IFNλ in chronic hepatitis B (CHB) patients. These patients were pretreated with directly acting antiviral therapy (entecavir) for 12 weeks with subsequent addition of peg-IFNλ for up to 32 weeks. In a subgroup of patients, the addition of peg-IFNλ provoked high serum levels of antiviral cytokine IL-18. We also observed the enhancement of natural killer cell polyfunctionality and the recovery of a pan-genotypic HBV-specific CD4+ T cells producing IFN-γ with maintenance of HBV-specific CD8+ T cell antiviral and cytotoxic activities. It was only in these patients that we observed strong virological control with reductions in both viral replication and HBV antigen levels. Here, we show for the first time that in vivo peg-IFNλ displays significant immunostimulatory properties with improvements in the main effectors mediating anti-HBV immunity. Interestingly, the maintenance in HBV-specific CD8+ T cells in the presence of peg-IFNλ is in contrast to previous studies showing that peg-IFNa treatment for CHB results in a detrimental effect on the functionality of this important antiviral T cell compartment

Observation of Y(2175) in J/ψ→ηϕf0(980)J/\psi\to \eta\phi f_0(980)

The decays of $J/\psi\to \eta\phi f_0(980) (\eta\to \gamma\gamma, \phi \to K^+K^-, f_0(980)\to\pi^+\pi^-)$ are analyzed using a sample of $5.8 \times 10^{7}$ $J/\psi$ events collected with the BESII detector at the Beijing Electron-Positron Collider (BEPC). A structure at around $2.18$GeV/$c^2$ with about $5\sigma$ significance is observed in the $\phi f_0(980)$ invariant mass spectrum. A fit with a Breit-Wigner function gives the peak mass and width of $m=2.186\pm 0.010 (stat)\pm 0.006 (syst)$GeV/$c^2$ and $\Gamma=0.065\pm 0.023 (stat)\pm 0.017 (syst)$GeV/$c^2$, respectively, that are consistent with those of Y(2175), observed by the BABAR collaboration in the initial-state radiation (ISR) process $e^+e^-\to\gamma_{ISR}\phi f_0(980)$. The production branching ratio is determined to be $Br(J/\psi\to\eta Y(2175))\cdot Br(Y(2175)\to\phi f_0(980))\cdot Br(f_0(980)\to\pi^+\pi^-)=(3.23\pm 0.75 (stat)\pm0.73 (syst))\times 10^{-4}$, assuming that the Y(2175) is a $1^{--}$ state.Comment: 5 pages, 4 figures, accepted by Phys. Rev. Let