1 research outputs found
Radical Cation Cycloadditions Using Cleavable Redox Auxiliaries
The incorporation
of an easily oxidized arylsulfide moiety facilitates
the photocatalytic generation of alkene radical cations that undergo
a variety of cycloaddition reactions with electron-rich reaction partners.
The sulfide moiety can subsequently be reductively cleaved in a traceless
fashion, affording products that are not otherwise directly accessible
using photoredox catalysis. This approach constitutes a novel oxidative
“redox auxiliary” strategy that offers a practical means
to circumvent a fundamental thermodynamic limitation facing photoredox
reactions