Pair-wise genetic versus geographic distance within HSAs.

<p>Pair-wise genetic versus geographic distance within HSAs.</p

Distribution of AHI and TDR according to the most frequently reported race/ethnicities in the dataset (A: White, B: Black, C: Hispanic) and number of each race/ethnicity reported in block groups in the 2010 Census (D: White, E: Black, F: Hispanic).

<p>Distribution of AHI and TDR according to the most frequently reported race/ethnicities in the dataset (A: White, B: Black, C: Hispanic) and number of each race/ethnicity reported in block groups in the 2010 Census (D: White, E: Black, F: Hispanic).</p

Pair-wise genetic distances for AHI cases, stratified by rural/urban status.

<p>Median genetic distance is indicated by a bar. HSAs 2 and 5 had only one rural case, so had no R-R genetic pairs.</p

Distribution of AHI and TDR cases by sex (A: men, B: women) and by mode of acquisition(C: men who have sex with men (MSM), D: heterosexual intercourse).

<p>Distribution of AHI and TDR cases by sex (A: men, B: women) and by mode of acquisition(C: men who have sex with men (MSM), D: heterosexual intercourse).</p

Spatial distribution of AHI and TDR positive census block groups (A) and Census-designated urban areas and major urban locations in North Carolina, with HSA boundaries (B).

<p>Spatial distribution of AHI and TDR positive census block groups (A) and Census-designated urban areas and major urban locations in North Carolina, with HSA boundaries (B).</p

Exploring Rural/Urban genetic variation.

<p>(A) Pair-wise genetic versus geographic distance for cases, classified as Rural-Urban, Urban-Urban or Rural-Rural based on CBG of patient at time of infection. (B) Genetic distances for all viruses, stratified by Rural/Urban pair relationship with median value indicated by a bar. R-R indicates both cases are from rural areas, R-U indicates one rural and one urban case, and U-U indicates both cases are from urban areas.</p

Exploring TDR versus non-TDR genetic and geographic variation.

<p>(A) Pair-wise genetic versus geographic distance for TDR and non-TDR viruses, and (B) TDR and non-TDR genetic distances by Rural/Urban pair relationship with median value indicated by a bar.</p

Urban/rural status of cases by race/ethnicity, risk groups and HSA designations.

<p>Urban/rural status of cases by race/ethnicity, risk groups and HSA designations.</p

Viral pair-wise genetic distances among young, black MSM risk patients, among other MSM patients, and among heterosexual risk patients, stratified by Rural/Urban pair relationship.

<p>Median genetic distance for each group is indicated by a bar.</p

Demographic and behavioral characteristics of AHI cases, stratified by drug sensitivity.

<p>Note that three drug susceptible and four drug resistant cases had no demographic and behavioral information available.</p