Protocol for assessing the effects of exogenous hormone administration on human postprandial glucose metabolism, appetite sensations, and food intake

Summary: Here, we present a protocol for a randomized, double-blind, placebo-controlled, crossover trial to evaluate the effects of a continuous intravenous infusion of a native liver-derived hormone, liver-expressed antimicrobial peptide 2 (LEAP2), on postprandial glucose metabolism, appetite and satiety sensations, and ad libitum food intake in humans. We describe the preparation of the exogenous hormone administration and participants. We then detail the liquid mixed meal, ad libitum meal test, and blood sampling procedures for assessing postprandial glucose metabolism and food intake.For complete details on the use and execution of this protocol, please refer to Hagemann et al. (2022).1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics

Vore folkeviser fra middelalderen : Studier over visernes aesthetik, rette form og alder /

Includes index.Bibliography: p. [327]Mode of access: Internet

CRT_optimal_DRYAD

Data collected during study period at the different phases (i.e. baseline, 3 months, and 6 months.) Questionnaires are SF-36 and LIfHE, each "@-number" corresponds to standard question. "Ventrikulaer_aktivitet" means ventricular activity