Shadow, Skin, and Surface; Examining the Work of Viviane Sassen

Viviane Sassen is a Dutch fashion photographer, whose personal work feature people from African descent. Through the employment of the equatorial light, her models’ personal identities and faces are left in the shadow, their dark skin rendered “just” black, depicting the sitters invisible and without personal recognition. In this thesis I offer an alternative to reading her work whose praise always stay on the surface; I examine her work in relation to the historical and geographical location, offer an analysis to the ontology of the shadow in photography, and examine the treatment of the surface of Sassen’s models

The Expected Adjustment and Academic Outcomes of Honors College Students

The transition to an institution of higher education can present challenges and difficulties, but it is a student\u27s expectations that can ultimately predict adjustment (Jackson, Pancer, Pratt, & Hunsberger, 2000). A larger number of students who experience difficulties in their adjustment end up withdrawing from the institution (Baker & Siryk, 1986). There is evidence that for some students there is a vast disconnect between their expectations regarding the institution of higher education, and the reality of their experiences. Students may not realize that what was expected of them in high school will differ greatly in college. It is this lack of understanding of the different expectations that can lead students to struggle academically, and can affect adjustment (Kern, Fagley, & Miller, 1998). Studies indicate that students who entered college with unrealistically high expectations were less successful academically than students with lower, but more accurate grade expectations (Smith & Wertlieb, 2005). High achieving college students may face unique challenges related to their overall adjustment (Rice, Leever, Christopher, & Porter, 2006). These challenges may also affect students\u27 expectations regarding adjustment. The current study followed a non-experimental ex post facto design. Data collected from the Transition to College Inventory was analyzed to assess expected academic, social, personal-emotional, and institutional adjustment of honors students and non-honors students. Additionally, the study examined expected adjustment and participation in honors programming as predictors of academic success and retention status. A random sample of Honors College students and non-honors students (N = 393) was utilized for the current study. Results indicate that there was a significant difference between honors students and non-honors student reports\u27 on expected adjustment. Additionally, factor 2 (Influences in college choice), and the group the student belonged to (honors vs. non-honors) were most influential in predicating first semester academic success

Subject To Change

Subject to Change is the culmination of a two-year investigation of the idea of home. This thesis discusses the journey of creating a home for my family and the work it spawned. Various cultural and artistic influences that shape the work include Grimm’s fairytales, my upbringing in Germany, Sigmund Freud, Bernd and Hilla Becher, and Josef Beuys. This work reflects a situation and transforms material that takes on symbolic meaning

Palliative Care Posters - 2019

Palliative Care Posters - 2019https://scholarlycommons.libraryinfo.bhs.org/research_education/1009/thumbnail.jp

Multi-omic studies on missense PLG variants in families with otitis media

Otitis media (OM), a very common disease in young children, can result in hearing loss. In order to potentially replicate previously reported associations between OM and PLG, exome and Sanger sequencing, RNA-sequencing of saliva and middle ear samples, 16S rRNA sequencing, molecular modeling, and statistical analyses including transmission disequilibrium tests (TDT) were performed in a multi-ethnic cohort of 718 families and simplex cases with OM. We identified four rare PLG variants c.112A > G (p.Lys38Glu), c.782G > A (p.Arg261His), c.1481C > T (p.Ala494Val) and c.2045 T > A (p.Ile682Asn), and one common variant c.1414G > A (p.Asp472Asn). However TDT analyses for these PLG variants did not demonstrate association with OM in 314 families. Additionally PLG expression is very low or absent in normal or diseased middle ear in mouse and human, and salivary expression and microbial a-diversity were non-significant in c.1414G > A (p.Asp472Asn) carriers. Based on molecular modeling, the novel rare variants particularly c.782G > A (p.Arg261His) and c.2045 T > A (p.Ile682Asn) were predicted to affect protein structure. Exploration of other potential disease mechanisms will help elucidate how PLG contributes to OM susceptibility in humans. Our results underline the importance of following up findings from genome-wide association through replication studies, preferably using multi-omic datasets.Peer reviewe

A mathematical model of contact tracing during the 2014-2016 west African ebola outbreak

The 2014-2016 West African outbreak of Ebola Virus Disease (EVD) was the largest and most deadly to date. Contact tracing, following up those who may have been infected through contact with an infected individual to prevent secondary spread, plays a vital role in controlling such outbreaks. Our aim in this work was to mechanistically represent the contact tracing process to illustrate potential areas of improvement in managing contact tracing efforts. We also explored the role contact tracing played in eventually ending the outbreak. We present a system of ordinary differential equations to model contact tracing in Sierra Leonne during the outbreak. Using data on cumulative cases and deaths we estimate most of the parameters in our model. We include the novel features of counting the total number of people being traced and tying this directly to the number of tracers doing this work. Our work highlights the importance of incorporatingchanging behavior into one’s model as needed when indicated by the data and reported trends. Our results show that a larger contact tracing program would have reduced the death toll of the outbreak. Counting the total number of people being traced and including changes in behavior in our model led to better understanding of disease management

HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma

CONTEXT: ERBB2 (erb-b2 receptor tyrosine kinase 2 or HER2) is currently the only biomarker established for selection of a specific therapy for patients with advanced gastroesophageal adenocarcinoma (GEA). However, there are no comprehensive guidelines for the assessment of HER2 in patients with GEA. OBJECTIVES: To establish an evidence-based guideline for HER2 testing in patients with GEA, to formalize the algorithms for methods to improve the accuracy of HER2 testing while addressing which patients and tumor specimens are appropriate, and to provide guidance on clinical decision making. DESIGN: The College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology convened an expert panel to conduct a systematic review of the literature to develop an evidence-based guideline with recommendations for optimal HER2 testing in patients with GEA. RESULTS: The panel is proposing 11 recommendations with strong agreement from the open-comment participants. RECOMMENDATIONS: The panel recommends that tumor specimen(s) from all patients with advanced GEA, who are candidates for HER2-targeted therapy, should be assessed for HER2 status before the initiation of HER2-targeted therapy. Clinicians should offer combination chemotherapy and a HER2-targeted agent as initial therapy for all patients with HER2-positive advanced GEA. For pathologists, guidance is provided for morphologic selection of neoplastic tissue, testing algorithms, scoring methods, interpretation and reporting of results, and laboratory quality assurance. CONCLUSIONS: This guideline provides specific recommendations for assessment of HER2 in patients with advanced GEA while addressing pertinent technical issues and clinical implications of the results

HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology

-ERBB2 (erb-b2 receptor tyrosine kinase 2 or HER2) is currently the only biomarker established for selection of a specific therapy for patients with advanced gastroesophageal adenocarcinoma (GEA). However, there are no comprehensive guidelines for the as

Social Science Applications in Sustainable Aviation Biofuels Research: Opportunities, Challenges, and Advancements

13-C-AJFF-WaSU-013This is an open access article under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) license https://creativecommons.org/licenses/by/4.0/. Please cite this article as: Anderson BJ, Mueller DW, Hoard SA, Sanders CM and Rijkhoff SAM (2022) Social Science Applications in Sustainable Aviation Biofuels Research: Opportunities, Challenges, and Advancements. Front. Energy Res. 9:771849. doi: 10.3389/fenrg.2021.771849Social science has an important role in aviation biofuels research, yet social science methods and approaches tend to be underdeveloped and under-utilized in the broader aviation biofuels literature and biofuels overall. Over the last 5 years, social science approaches in aviation biofuels research, particularly site-selection, have made several advances. Where early site-selection models either entirely excluded social science concepts or included only a few measurements using poor proxies, current models more accurately, and more comprehensively capture key social science concepts to better examine and predict project implementation success and long-term sustainability. Despite several studies published within the last 20 years noting the need for more empirical studies of social sustainability and improvement in incorporation of social criteria, progress has remained rather stagnant in several areas. To help move the field forward, we conduct a review of the current state of social science research in aviation biofuels with a focus on sustainability, site-selection, and public acceptance research, identifying key approaches, important developments, and research gaps and weaknesses of current approaches. While several review studies already exist, they tend to focus on a single area of biofuels such as public acceptance. By broadening our review to several areas, we are able to identify several common limitations across these areas that contribute to the continued underutilization of social science approaches in aviation biofuels. This includes the preference for practical and reliable indicators for social criteria that prioritize quantitative methods over other approaches. Based on these limitations, we make several recommendations to improve social science research in aviation biofuels, including ensuring that social scientists are key members of the research team, the adoption of a mixed-methods research designs that combines quantitative and qualitative approaches that better measure some criteria and local-level impacts, and adequate resources for social science research throughout biofuel development projects as these methods are often more time-consuming and costly to implement. We argue that implementing these recommendations in future aviation biofuel development projects will improve social science approaches utilized in aviation biofuels research and address a long acknowledged gap in the field