1,722 research outputs found

    Unsafe Harbor: The European Union\u27s Demand for Heightened Data Privacy Standards in \u3cem\u3eSchrems v. Irish Data Protection Commissioner\u3c/em\u3e

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    In 1995, the European Union adopted the Data Protection Directive to govern the processing, use, and exchange of personal data. The United States refused to enact similar legislation, consequently jeopardizing ongoing and future data transfers with the European Union. To prevent economic catastrophe, the United States negotiated with the European Union to reach the Safe Harbor Agreement and, on July 26, 2000, the European Commission formally recognized the agreement as compliant with the Data Protection Directive in its Safe Harbor Decision. In 2013, U.S. data protection standards were once again placed under the microscope when Edward Snowden leaked information regarding the National Security Agency’s surveillance activities. In the wake of these leaks, Maximillian Schrems filed a complaint with the Irish Data Protection Commissioner, claiming that Facebook was not adequately protecting his personal data from National Security Agency surveillance when transferring it from its European Union servers to its U.S. servers. On October 6, 2015, the European Court of Justice invalidated the Safe Harbor Decision in Schrems v. Irish Data Protection Commissioner. This Comment examines the court’s reasoning and argues that the court erred in interpreting Article 25 of the Data Protection Directive and overstepped jurisdictional boundaries

    Two Color Entanglement

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    We report on the generation of entangled states of light between the wavelengths 810 and 1550 nm in the continuous variable regime. The fields were produced by type I optical parametric oscillation in a standing-wave cavity build around a periodically poled potassium titanyl phosphate crystal, operated above threshold. Balanced homodyne detection was used to detect the non-classical noise properties, while filter cavities provided the local oscillators by separating carrier fields from the entangled sidebands. We were able to obtain an inseparability of I=0.82, corresponding to about -0.86 dB of non-classical quadrature correlation.Comment: 4 pages, 2 figure

    Dynamic retinoscopies: Are they reliable?

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    The goal of this project was to establish the intraexaminer and interexaminer reliability of MEM, Book, Bell and Stresspoint retinoscopies, and secondly to compare findings of the different techniques to each other and to near autorefractor measurements. The four retinoscopies were performed on thirty-one children three times each by four retinoscopists. Identity of the children and the power of all lenses used in the study were concealed from the retinoscopists. Results indicate good intrarater reliability of all four techniques and poorer interrater reliability. Bell retinoscopy was statistically the most reliable of the four. The four techniques produced statistically different, though strongly correlated, results. None were well correlated with near autorefractor measurements

    Millimeter-wave diode-grid phase shifters

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    Monolithic diode grids have been fabricated on 2-cm square gallium-arsenide wafers with 1600 Schottky-barrier varactor diodes. Shorted diodes are detected with a liquid-crystal technique, and the bad diodes are removed with an ultrasonic probe. A small-aperture reflectometer that uses wavefront division interference was developed to measure the reflection coefficient of the grids. A Phase shift of 70° with a 7-dB loss was obtained at 93 GHz when the bias on the diode grid was changed from -3 V to 1 V. A simple transmission-line grid model, together with the measured low-frequency parameters for the diodes, was shown to predict the measured performance over the entire capacitive bias range of the diodes, as well as over the complete reactive tuning range provided by a reflector behind the grid, and over a wide range of frequencies form 33 GHz to 141 GHz. This shows that the transmission-line model and the measured low-frequency diode parameters can be used to design an electronic beam-steering array and to predict its performance. An electronic beam-steering array made of a pair of grids using state-of-the-art diodes with 5-Ω series resistances would have a loss of 1.4 dB at 90 GHz

    Millimeter-Wave Diode-Grid Frequency Doubler

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    Monolithic diode grid were fabricated on 2-cm^2 gallium-arsenide wafers in a proof-of-principle test of a quasi-optical varactor millimeter-wave frequency multiplier array concept. An equivalent circuit model based on a transmission-line analysis of plane wave illumination was applied to predict the array performance. The doubler experiments were performed under far-field illumination conditions. A second-harmonic conversion efficiency of 9.5% and output powers of 0.5 W were achieved at 66 GHz when the diode grid was pumped with a pulsed source at 33 GHz. This grid had 760 Schottky-barrier varactor diodes. The average series resistance was 27 Ω, the minimum capacitance was 18 fF at a reverse breakdown voltage of -3 V. The measurements indicate that the diode grid is a feasible device for generating watt-level powers at millimeter frequencies and that substantial improvement is possible by improving the diode breakdown voltage

    Reconstituted high-density lipoproteins promote wound repair and blood flow recovery in response to ischemia in aged mice

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    Background: The average population age is increasing and the incidence of age-related vascular complications is rising in parallel. Impaired wound healing and disordered ischemia-mediated angiogenesis are key contributors to age-impaired vascular complications that can lead to amputation. High-density lipoproteins (HDL) have vasculo-protective properties and augment ischemia-driven angiogenesis in young animals. We aimed to determine the effect of reconstituted HDL (rHDL) on aged mice in a murine wound healing model and the hindlimb ischemia (HLI) model. Methods: Murine wound healing model—24-month-old aged mice received topical application of rHDL (50 μg/wound/ day) or PBS (vehicle control) for 10 days following wounding. Murine HLI model—Femoral artery ligation was performed on 24-month-old mice. Mice received rHDL (40 mg/kg) or PBS, intravenously, on alternate days, 1 week pre-surgery and up to 21 days post ligation. For both models, blood flow perfusion was determined using laser Doppler perfusion imaging. Mice were sacrificed at 10 (wound healing) or 21 (HLI) days post-surgery and tissues were collected for histological and gene analyses. Results: Daily topical application of rHDL increased the rate of wound closure by Day 7 post-wounding (25 %, p < 0.05). Wound blood perfusion, a marker of angiogenesis, was elevated in rHDL treated wounds (Days 4–10 by 22–25 %, p < 0. 05). In addition, rHDL increased wound capillary density by 52.6 %. In the HLI model, rHDL infusions augmented blood flow recovery in ischemic limbs (Day 18 by 50 % and Day 21 by 88 %, p < 0.05) and prevented tissue necrosis and toe loss. Assessment of capillary density in ischemic hindlimb sections found a 90 % increase in rHDL infused animals. In vitro studies in fibroblasts isolated from aged mice found that incubation with rHDL was able to significantly increase the key pro-angiogenic mediator vascular endothelial growth factor (VEGF) protein (25 %, p < 0.05). Conclusion: rHDL can promote wound healing and wound angiogenesis, and blood flow recovery in response to ischemia in aged mice. Mechanistically, this is likely to be via an increase in VEGF. This highlights a potential role for HDL in the therapeutic modulation of age-impaired vascular complications

    Segmented forefoot plate in basketball footwear: Does it influence performance and foot joint kinematics and kinetics?

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    This study examined the effects of shoes’ segmented forefoot stiffness on athletic performance and ankle and metatarsophalangeal joint kinematics and kinetics in basketball movements. Seventeen university basketball players performed running vertical jumps and 5-msprints atmaximumeffort with 3 basketball shoes of various forefoot plate conditions (medial plate, medial + lateral plates, and no-plate control). One-way repeated measures ANOVAs were used to examine the differences in athletic performance, joint kinematics, and joint kinetics among the 3 footwear conditions (α = .05). Results indicated that participants wearing medial + lateral plates shoes demonstrated 2.9% higher jump height than those wearing control shoes (P = .02), but there was no significant differences between medial plate and control shoes (P \u3e .05). Medial plate shoes produced greater maximum plantar flexion velocity than the medial + lateral plates shoes (P \u3c .05) during sprinting. There were no significant differences in sprint time. These findings implied that inserting plates spanning both the medial and lateral aspects of the forefoot could enhance jumping, but not sprinting performances. The use of a medial plate alone, although induced greater plantar flexion velocity at the metatarsophalangeal joint during sprinting, was not effective in improving jump heights or sprint times

    A CT Image Denoising Method with Residual Encoder-Decoder Network

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    Utilizing a low-dose CT approach significantly reduces the radiation exposure for patients, yet it introduces challenges, such as increased noise and artifacts in the resultant images, which can hinder accurate medical diagnostics. Traditional methods for noise reduction struggle with preserving image textures due to the complexity of modeling statistical properties directly within the image domain. To address these limitations, this study introduces an enhanced noise-reduction technique centered around an advanced residual encoder-decoder network. By incorporating recursive processing into the foundational network, this method reduces computational complexity and enhances the effectiveness of noise reduction. Furthermore, the introduction of a root-mean-square error and perceptual loss functions aims to retain the integrity of the images' textural details. The enhanced technique also includes optimized tissue segmentation, improving artifact management post-improvement. Validation using the TCGA-COAD clinical dataset demonstrates superior performance in both noise reduction and image quality, as measured by post-denoising PSNR and SSIM, compared to the existing WGAN approach. This advancement in CT image processing offers a practical solution for clinical applications, achieving lower computational demands and faster processing times without compromising image quality.Comment: 7 pages, 2 figures, 1 table, work under preparatio

    Rural Health in Virginia: Disparities, Dilemmas, and Overview of a JMU School of Nursing Solution

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    Background: There is no unified definition of rurality; this makes studying rurality, rural health, and associated health disparities and health outcomes difficult. Rural Americans constitute approximately 15% of the U.S. population, and they experience multiple barriers to healthcare and numerous health disparities as a result, particularly related to chronic disease, mental health, and increased lifestyle-linked health risks. Rural Americans should be viewed as a unique and vulnerable population, one with specific health promotion and disease prevention needs. Local problem: Although Virginia as a whole is a wealthy state, much inequity exists between the “Golden Crescent” and the “Rural Horseshoe” regions of Virginia, which includes the western portion of the State. Rural Virginians face higher unemployment, a higher poverty rate, and decreased access to care. One such area is Page County, Virginia, a local underserved health professional shortage area. Methods: In 2018, JMU obtained a HRSA grant focusing on Nursing Education, Practice, Quality, and Retention called, “The Undergraduate Primary Care and Rural Education (UPCARE) Project: a Community-based Nursing Education Collaboration. Intervention: The UPCARE Project allows JMU School of Nursing to respond to the needs for 1) BSN student education focusing on community health and primary care in a rural area, and 2) the creation two RN preceptor positions which incorporate a enhanced primary care RN role within 4 Rural Health Clinics (RHCs), all of whom are facilitated by a faculty-led grant team, including a Nurse Liaison. This two-pronged approach enables nurses to work to meet the health needs of the residents of Page County, Virginia. It is an innovative approach in keeping with Virginia’s State Rural Health Plan. Results: The JMU UPCARE Project is a collaborative, community-focused solution to the rural health disparities facing Page County. To date, nine students have started their clinical experiences in Page County, and two RN preceptors are starting their enhanced primary care RN role in the Rural Health Clinics. Conclusions/ Implications: This presentation will focus on rural health nursing in general, rural health disparities in Virginia, the creation of the UPCARE Project as part of the solution to meet the health care needs of rural Virginians. In keeping with the theme of the conference, the presentation will focus on the development of an enhanced primary care RN role, which is designed for RNs to work at the top of their practice scope
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