170 research outputs found
Robust free-breathing SASHA T1 mapping with high-contrast image registration
Comparison of free-breathing SASHA-VFA images with navigator gating, normal image registration, and high-contrast image registration. (GIF 4289Â kb
A simple method for characterizing left ventricular remodeling by cardiovascular magnetic resonance
Degree of diffuse fibrosis measured by MRI correlates with LV remodelling in childhood cancer survivors after anthracycline chemotherapy
Ocular Penetration of N-Formimidoyl Thienamycin (MK-787) and Potentiation by Dipeptidase Inhibitor (MK-791)
N-formimidoyl thienamycin (MK-787) is a new /?-lactam with potent activity against both aerobic and anaerobic gram-positive and gram-negative bacteria. Its spectrum and activity suggest it may be useful in treatment of complicated intraocular infections. Its ocular penetration was studied in New Zealand white rabbits immediately before and after the third dose of 40 mg/kg administered intravenously at q6h intervals. Plasma, aqueous humor, and vitreous humor were obtained by direct aspiration, and antibiotic levels were asayed using an agar well diffusion method. MK-787 penetrated uninflamed intraocular fluids, including vitreous humor, although vitreous concentrations achieved (0.1-0.2 Mg/ml) were significantly lower than the mean peak plasma (15 Mg/ml) and aqueous concentrations (7 Mg/ml). Nevertheless, the intraocular levels attained approached or exceeded the MIC 90 and markedly enhanced spectrum of activity against both gram-positive and gram-negative bacteria
Characterization of myocardial T1 and partition coefficient as a function of time after gadolinium delivery in healthy subjects
Quantitative CMR perfusion imaging identifies reduced flow reserve in microvascular coronary artery disease
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Accuracy and reproducibility of four T1 mapping sequences: a head-to-head comparison of MOLLI, ShMOLLI, SASHA, and SAPPHIRE
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