DRESS syndrome after short-time exposure to ciprofloxacin

Mujer de 38 años con diagnóstico inicial de infección del tracto urinario (ITU) tratada por cinco días con ciprofloxacino. Al tgercer día de tratamiento, presento fiebre, edema palpebral y erupciones cutáneas en más del 50% del cuerpo asociadas a prurito. Al ingreso, se inició ceftriaxona considerando una ITU complicada. Al octavo día, se evidenció eosinofilia y se diagnosticó síndrome DRESS, siendo tratada con clorfenamina y ranitidina, consiguiendo la remisión progresiva del cuadro inicial.A 38-year-old woman with an initial diagnosis of urinary tract infection (UTI) was treated for five days with ciprofloxacin. On the third day of treatment, she presented fever, eyelid edema and rash over 50% of the body associated with pruritus. On admission, ceftriaxone was started considering a complicated UTI. On the eighth day, eosinophilia was evidenced and DRESS syndrome was diagnosed, being treated with chlorphenamine and ranitidine, achieving progressive remission of the initial symptoms