Gaussian Message Passing for Overloaded Massive MIMO-NOMA

This paper considers a low-complexity Gaussian Message Passing (GMP) scheme for a coded massive Multiple-Input Multiple-Output (MIMO) systems with Non-Orthogonal Multiple Access (massive MIMO-NOMA), in which a base station with $N_s$ antennas serves $N_u$ sources simultaneously in the same frequency. Both $N_u$ and $N_s$ are large numbers, and we consider the overloaded cases with $N_u>N_s$. The GMP for MIMO-NOMA is a message passing algorithm operating on a fully-connected loopy factor graph, which is well understood to fail to converge due to the correlation problem. In this paper, we utilize the large-scale property of the system to simplify the convergence analysis of the GMP under the overloaded condition. First, we prove that the \emph{variances} of the GMP definitely converge to the mean square error (MSE) of Linear Minimum Mean Square Error (LMMSE) multi-user detection. Secondly, the \emph{means} of the traditional GMP will fail to converge when $N_u/N_s< (\sqrt{2}-1)^{-2}\approx5.83$. Therefore, we propose and derive a new convergent GMP called scale-and-add GMP (SA-GMP), which always converges to the LMMSE multi-user detection performance for any $N_u/N_s>1$, and show that it has a faster convergence speed than the traditional GMP with the same complexity. Finally, numerical results are provided to verify the validity and accuracy of the theoretical results presented.Comment: Accepted by IEEE TWC, 16 pages, 11 figure

User Activity Detection and Channel Estimation for Grant-Free Random Access in LEO Satellite-Enabled Internet-of-Things

With recent advances on the dense low-earth orbit (LEO) constellation, LEO satellite network has become one promising solution to providing global coverage for Internet-of-Things (IoT) services. Confronted with the sporadic transmission from randomly activated IoT devices, we consider the random access (RA) mechanism, and propose a grant-free RA (GF-RA) scheme to reduce the access delay to the mobile LEO satellites. A Bernoulli-Rician message passing with expectation maximization (BR-MP-EM) algorithm is proposed for this terrestrial-satellite GF-RA system to address the user activity detection (UAD) and channel estimation (CE) problem. This BR-MP-EM algorithm is divided into two stages. In the inner iterations, the Bernoulli messages and Rician messages are updated for the joint UAD and CE problem. Based on the output of the inner iterations, the expectation maximization (EM) method is employed in the outer iterations to update the hyper-parameters related to the channel impairments. Finally, simulation results show the UAD and CE accuracy of the proposed BR-MP-EM algorithm, as well as the robustness against the channel impairments.Comment: 14 pages, 9 figures, accepted by Internet of Things Journa

DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1.

Let-7 miRNAs act as tumour suppressors by directly binding to the 3\u27UTRs of downstream gene products. The regulatory role of let-7 in downstream gene expression has gained much interest in the cancer research community, as it controls multiple biological functions and determines cell fates. For example, one target of the let-7 family is cyclin D1, which promotes G0/S cell cycle progression and oncogenesis, was correlated with endoribonuclease DICER1, another target of let-7. Down-regulated let-7 has been identified in many types of tumours, suggesting a feedback loop may exist between let-7 and cyclin D1. A potential player in the proposed feedback relationship is Dicer, a central regulator of miRNA expression through sequence-specific silencing. We first identified that DICER1 is the key downstream gene for cyclin D1-induced let-7 expression. In addition, we found that let-7 miRNAs expression decreased because of the p53-induced cell death response, with deregulated cyclin D1. Our results also showed that cyclin D1 is required for Nutlin-3 and TAX-induced let-7 expression in cancer repression and the cell death response. For the first time, we provide evidence that let-7 and cyclin D1 form a feedback loop in regulating therapy response of cancer cells and cancer stem cells, and importantly, that alteration of let-7 expression, mainly caused by cyclin D1, is a sensitive indicator for better chemotherapies response

Spectral self-adaptive absorber/emitter for harvesting energy from the sun and outer space

The sun (~6000 K) and outer space (~3 K) are the original heat source and sink for human beings on Earth. The energy applications of absorbing solar irradiation and harvesting the coldness of outer space for energy utilization have attracted considerable interest from researchers. However, combining these two functions in a static device for continuous energy harvesting is unachievable due to the intrinsic infrared spectral conflict. In this study, we developed spectral self-adaptive absorber/emitter (SSA/E) for daytime photothermal and nighttime radiative sky cooling modes depending on the phase transition of the vanadium dioxide coated layer. A 24-hour day-night test showed that the fabricated SSA/E has continuous energy harvesting ability and improved overall energy utilization performance, thus showing remarkable potential in future energy applications.Comment: 15 pages, 4 figure

The Sustainable Effect of Operational Performance on Financial Benefits: Evidence from Chinese Quality Awards Winners

Quality management practices have become increasingly important as firms seek to obtain quality certifications to dominate markets. To date, adequate research evaluating the effects of quality management is lacking. In this work, we used Chinese quality awards to evaluate a firm&rsquo;s quality level. A PSM-DiD (propensity score matching and difference-in-difference) model describing the relationship between quality award effects and financial benefits in terms of return on assets was developed. We further used a hierarchical regression to examine the influence of operational performance on financial benefits. The results show that quality awards cannot assure their winners a higher return on asset. Indicators of operating performance, such as less lead time and higher inventory turnover, can significantly enhance firms&rsquo; profitability. The moderating effects of operational performance suggest that firms may focus on how to translate quality management practices into business improvement. This study also contributes to the operation management literature by describing how firms need outstanding financial performance for sustainable development and continuous improvement