Diphoton plus ZZ production at the ILC at O(α4){\cal O}(\alpha^4)

Precision measurement for the production of a $Z$-boson in association with two photons is important for investigating the Higgs boson and exploring new physics at the International Linear Collider. It could be used to study the $ZZ\gamma\gamma$ anomalous quartic gauge coupling. In this work we report on our calculation of the full ${\cal O} (\alpha^4)$ contributions to the $e^+e^- \to Z \gamma\gamma$ process in the standard model, and we analyze the electroweak (EW) quantum effects on the total cross section. We investigate the dependence of the $Z\gamma\gamma$ production rate on the event selection scheme and provide distributions for some important kinematic observables. We find that the next-to-leading order (NLO) EW corrections can enhance the total cross section quantitatively from $2.32\%$ to $9.61\%$ when the colliding energy goes up from $250 GeV$ to $1 TeV$, and the NLO EW corrections show obviously a non trivial phase space dependence. We conclude that in studying the signal process $e^+e^- \to ZH \to Z \gamma\gamma$, the background process $e^+e^- \to Z \gamma\gamma$ can be suppressed significantly if we take appropriate kinematic cuts on the final products.Comment: 18 pages, 10 figure

MiR-574-5p alleviates sepsis-induced acute lung injury by regulating TRAF6/NF-κB pathway

Purpose: To investigate the protective effect of miR-574-5p pretreatment against acute lung injury (ALI) induced by sepsis.Methods: A male C57BL/6 mouse model of sepsis-induced ALI was established by cecal ligation and puncture (CLP) and treated with miR-574-5p agomir (intravenous injection, 80 mg/kg per day, 3 days). After that, blood and lung samples were obtained for histopathological observation. Myeloperoxidase (MPO) activity, inflammatory cell infiltration, and cytokine expression were analyzed. The target gene of miR-574-5p was predicted using TargetScan prediction, and verified by luciferase assay and western blot.Results: In sepsis-induced ALI mice model, downregulation of miR-574-5p was observed. Pretreatment of miR-574-5p significantly alleviated ALI by suppressing histological damage, and reducing MPO activity and inflammatory cell infiltration, as well as decreasing cytokine expression. The  underlying mechanism was that miR-574-5p targeted TNF receptor associated factor 6 (TRAF6) and suppressed the downstream NF-κB pathway. Moreover, TRAF6 overexpression reversed the effects of miR-574-5p on ALI.Conclusion: MiR-574-5p pretreatment suppresses inflammatory responses, thus reducing lung injury induced by sepsis in mice, partly via the regulation of TRAF6 and NF-κB pathway. Therefore, this approach can potentially be used for the clinical management of ALI in humans Keywords: Sepsis, Acute lung injury, MiR-574-5p, TRAF6, NF-κB pathwa

Comparison Analysis of Dust-Depressor Using Microbial Induced Carbonate Precipitation with Urease Reagent

The dust-depressors have been developed utilizing a method of microbial induced carbonate precipitation. This microbial dust-depressor has the characteristics of high efficiency for dust suppression and environmental protection. Optimal compositions of urease dust-depressor and microbial dust-depressor have been studied. In addition, pure water, CaCl2 and super absorbent polymer are chosen to compare with new dust-depressors on the performances. The results showed that the microbial dust-depressor had 3.13 mm/min of seepage velocity and 79.1% of dust suppression efficiency, which were superior to other dust-depressors on the performance of seepage velocity and dust suppression efficiency