874 research outputs found

    Privacy Perils of Open Data and Data Sharing: A Case Study of Taiwan\u27s Open Data Policy and Practices

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    Governments and private sector players have hopped on the open data train in the past few years. Both the governments and civil society in Taiwan are exploring the opportunities provided by the data stored in public and private sectors. While they have been enjoying the benefits of the sharing and flowing of data among various databases, the government and some players in the private sectors have also posed tremendous privacy challenges by inappropriately gathering and processing personal data. The amended Personal Data Protection Act was originally enacted as a regulatory mechanism to protect personal data and create economic benefits via enhancing the uses of public and private sector data. In reality, the Act has instead resulted in harm to Taiwan’s data privacy situation in this big data era. This article begins with an overview of the Taiwan’s open data policy history and its current practices. Next, the article analyzes cases in which the data sharing practices between different sectors have given rise to privacy controversies, with a particular focus on 2020, when Taiwan used data surveillance in response to the COVID-19 pandemic. Finally, this article flags problems related to an open data system, including the protection of sensitive data, de-identification, the right to consent and opt-out, and the ambiguity of “public interest,” and concludes by proposing a feasible architecture for the implementation of a more sensible open data system with privacy-enhancing characteristics

    Biomechanical Characteristics and EMG Activities of Weighted Countermovement Jump

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    The purpose of this study was to investigate the biomechanical characteristics and EMG activities during a weighted countermovement jump (WCMJ) with 0%, 25% and 50% of body weight. Eight male college students participated this study. An AMTI force platform, Penny&Giles goniometer and Biovision EMG system were used synchronously to record the related parameters while subjects performed WCMJs. The results indicate that by increasing load, the eccentric mean force, the maximum force and concentric impulse increases significantly. With the load increase, the EMG activities of soleus and gastrocnemius did not changed significantly, while the eccentric mean EMG amplitude of rectus femoris got greater. This reveals that WCMJ has a marked influence on the lower extremity, especially on the rectus femoris

    THE REGULATION OF LEG STIFFNESS AND EMG ACTIVITIES ON PERSON WITH VISUAL IMPAIRED DURING STEP-DOWN WALKING

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    The purpose of present study was to evaluate leg muscular regulation and neuromuscular activation by investigating the stiffness and EMG amplitude of normal vision students and visually impaired students. 10 normal vision (age: 24.3±20 years; height: 171.5±4.6cm; mass: 65.9±8.0kg) and 10 visually impaired students (age: 23.2±2.4 years; height: 163.4±9.6cm; mass: 62.8±15.0kg) were served as subjects. AMTI force platform (1200 Hz), Peak Performance motion analysis system (60Hz) and Biovision EMG system were used synchronously to record the ground reaction force, the kinematic parameters and EMG signals of lower extremity during the subjects stepped down from height 20, 30 and 40cm. The results revealed that the regulation of neuromuscular system of the impaired is less efficient compared to the normal one because of lower muscle stiffness and EMG activity

    単純リグレットバンディットアルゴリズムを利用したモンテカルロ木探索

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    学位の種別: 課程博士審査委員会委員 : (主査)東京大学准教授 鶴岡 慶雅, 東京大学教授 相田 仁, 東京大学准教授 佐藤 周行, 東京大学教授 田浦 健次朗, 東京大学准教授 長谷川 禎彦University of Tokyo(東京大学

    Floating Point Arithmetic Protocols for Constructing Secure Data Analysis Application

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    AbstractA large variety of data mining and machine learning techniques are applied to a wide range of applications today. There- fore, there is a real need to develop technologies that allows data analysis while preserving the confidentiality of the data. Secure multi-party computation (SMC) protocols allows participants to cooperate on various computations while retaining the privacy of their own input data, which is an ideal solution to this issue. Although there is a number of frameworks developed in SMC to meet this challenge, but they are either tailored to perform only on specific tasks or provide very limited precision. In this paper, we have developed protocols for floating point arithmetic based on secure scalar product protocols, which is re- quired in many real world applications. Our protocols follow most of the IEEE-754 standard, supporting the four fundamental arithmetic operations, namely addition, subtraction, multiplication, and division. We will demonstrate the practicality of these protocols through performing various statistical calculations that is widely used in most data analysis tasks. Our experiments show the performance of our framework is both practical and promising

    Sample-Specific Debiasing for Better Image-Text Models

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    Self-supervised representation learning on image-text data facilitates crucial medical applications, such as image classification, visual grounding, and cross-modal retrieval. One common approach involves contrasting semantically similar (positive) and dissimilar (negative) pairs of data points. Drawing negative samples uniformly from the training data set introduces false negatives, i.e., samples that are treated as dissimilar but belong to the same class. In healthcare data, the underlying class distribution is nonuniform, implying that false negatives occur at a highly variable rate. To improve the quality of learned representations, we develop a novel approach that corrects for false negatives. Our method can be viewed as a variant of debiased constrastive learning that uses estimated sample-specific class probabilities. We provide theoretical analysis of the objective function and demonstrate the proposed approach on both image and paired image-text data sets. Our experiments demonstrate empirical advantages of sample-specific debiasing

    EBV-positive Hodgkin lymphoma is associated with suppression of p21cip1/waf1 and a worse prognosis

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    <p>Abstract</p> <p>Background</p> <p>About 30-50% of Hodgkin lymphomas (HLs) harbor the Epstein-Barr virus (EBV), but the impact of EBV infection on clinical outcomes has been unclear. EBV-encoded small RNAs (<it>EBER</it>s) are presented in all EBV-infected cells, but their functions are still less understood.</p> <p>Results</p> <p><it>EBER1 </it>was transfected into two HL cell lines, KMH2 and L428, and microarrays were used to screen for <it>EBER1</it>-induced changes. We found that <it>EBER1 </it>suppressed <it>p21</it><sup>cip1/waf1 </sup>transcription in HL cell lines. In addition, positive regulators of <it>p21</it><sup>cip1/waf1 </sup>transcription, such as p53, EGR1, and STAT1, were decreased. Suppression of <it>p21</it><sup>cip1/waf1 </sup>in the <it>EBER1</it><sup>+ </sup>HL cell lines was associated with increased resistance to histone deacetylase inhibitors or proteasome inhibitors, drugs known to cause apoptosis by increasing p21<sup>cip1/waf1 </sup>levels. On biopsy specimens, EBV<sup>+ </sup>HLs had weaker expression of both p21<sup>cip1/waf1 </sup>and active caspase 3. Clinically, suppression of p21<sup>cip1/waf1 </sup>in EBV<sup>+ </sup>HLs was associated with a worse 2-year disease-free survival rate (45% for EBV<sup>+ </sup>HLs <it>vs</it>. 77% for EBV<sup>- </sup>HLs, <it>p </it>= 0.002).</p> <p>Conclusion</p> <p>Although the underlying mechanisms are still relatively unclear, <it>EBER1 </it>inhibits <it>p21</it><sup>cip1/waf1 </sup>transcription and prevents apoptosis through down-regulation of p53, EGR1, and STAT1. The anti-apoptotic activity of <it>EBER1 </it>may be important in the rescue of Reed-Sternberg cells from drug-induced apoptosis and in the clinical behaviors of EBV<sup>+ </sup>HLs.</p

    Immune reconstitution inflammatory syndrome of Kaposi’s sarcoma in an HIV-infected patient

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    We present a case of Kaposi’s sarcoma-related immune reconstitution inflammatory syndrome in an HIV-infected patient who developed fever, worsening pulmonary infiltrates with respiratory distress, and progression of skin tumors at the popliteal region and thigh that resulted in limitation on movement of the right knee joint at 3.5 months following a significant increase of CD4 count after combination antiretroviral therapy
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