Histology and histomorphometry ISA file (Metadata)

<p>The file contains (i) general information on the experiment and the protocols related to the dissection and histology and histomorphometry evaluations on the “i_Organism” tab, (ii) information on each animal in the “s_Organism” tab, (iii) information on the samples that were measured in the “s_DP_Histo” tab, (iv) the links between the metadata and the histopathology measurements given in the Data records 15 in the "a_DP_Histopathology” tab, (v) the links between<br>the metadata and the histomorphometry measurements given in the Data records 15<br>in the “a_DP_Histomorphometry” tab</p

Hematology ISA file (Metadata)

<p>The file contains (i) general information on the experiment and the protocols related to the dissection and hematology measurement on the “i_Organism” tab, (ii) information on each animal in the “s_Organism” tab, (iii) information on the samples that were measured in the “s_DP_Hematology” tab, and (iv) information on the measurements performed for hematology in the “a_DP_Hematology” tab.</p

Body weight ISA file (Metadata)

<p>The file contains (i) general information on the experiment and the protocols related to exposure and body weight measurement on the “i_Organism” tab, (ii) information on each animal in the “s_Organism” tab, (iii) information on the body weight measurement in the “a_Organism_BodyWeight”.</p

Lung function Raw Data

<p>Three consecutive perturbations were performed to record acceptable measurements (coefficient of determination >0.95) for each individual subject. FlexiVent software (SCIREQ) was used to analyze and calculate lung mechanics parameters. Measurements arepresented as a data matrix. Briefly, it has the animal number information on the first row and the exposure group information in the second row. Then, the first column has the name of the lung function parameter measured.</p

Body weight Raw Data

<p>The file shows the animal number information on the first row and the exposure group information in the second row. Then, the first column has the study day information, and each body weight recorded (in grams) is recorded in corresponding cells.</p

BALF FACS analyses reports

<p>pdf reports of all BALF FACS analyses</p

Lung Histopathology and Histomorphometry Raw Data

<p>The file contains histopathology scores and histomorphometry measurements . Briefly, it has the exposure group information on the first row, the time point information on the second row, and the animal number information in the third row. Then, the first column has the name of the finding evaluated, or the parameter in the histomorphometry measured and the second column the level at which this was done.</p

Smoke chemistry

<p>The file contains the concentrations of 58 harmful and potentially harmful constituents measured in aerosols from 3R4F and the pMRTP.</p

Proteomics 2D gel ISA file (Metadata)

<p>The file contains (i) general information on the experiment and the protocols related to 2d gel proteomics on the “i_Organism” tab, (ii) information on each animal in the “s_Organism” tab, (iii) information on the samples that were measured in the “s_DP_Prot” tab, (iv) the links between the metadata and the image files given in the Data records 17 in the “a_DP_Prot” tab, (v) information on the data that was normalized in the “s_PR_Prot” tab, (vi) the links between the metadata and the normalized matrix given in the file 2D-PAGE data - normalized matrix</p

2D-PAGE data - normalized matrix

<p>Normalilzed matrix of protein measurements in lung by 2d-gel analysis.</p