603 research outputs found

    Knowledge-based View in the Franchising Research Literature

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    Abstract. This study was conducted to understand the state of research on applications of Knowledge-based View in franchise systems. First, we used SALSA (Search, Appraisal, Synthesis, and Analysis), a simple systematic data search method, to obtain 61 sample papers. Second, the citations of authors and publications were analyzed using the bibliometric method to understand the authors and the publications that had the most impact as well as the trend of current studies in the field of knowledge-based theory application in franchise systems. The results showed that the journals that had the most publications on the topic were Entrepreneurship Theory and Practice and Journal of Business Research; the most cited author was S.A. Shane, who had an average rate of 1.016 citations per article, and the most cited study was a paper published by Darr, Argote, & Epple (1995), which was cited by 18 of the 61 sample papers (18/61, 29.51%). Third, we categorized the topic of knowledge-based theory application in franchise systems into six categories, i.e., knowledge transfer, knowledge creation, knowledge sharing, knowledge application, organizational learning, and knowledge exchange, to provide references for future studies.Keywords. Knowledge-based view; Franchising; Bibliometrics.JEL. L10

    THE KINEMATIC ANALYSIS of BASKETBALL THREE POINT SHOOT AFTER HIGH INTENSITY PROGRAM

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    The purpose of this study was to analyze kinetic and kinematic characteristics of three points shooting by high speed camera. Basketball players have to finish the high intensity program which was designed from simulative basketball games. The high intensity testing program includes dribbling, sprint, slide, jump shooting and three points shooting. The results of the experiments indicated that elbow, wrist, hip and ankle joints angle velocities would decrease, except the knee joint, after the high intensity program. The knee angle of take-off would also increase. It indicated that the upper limb joints angular velocity would decrease and players had to increase knee joint angular velocity to maintain original power. The time from take-off to ball release also decreased which means that there was a change in the coordinates in knee joint and elbow joint. After high intensity program the elbow and knee joints extension were closed to produce more power for the shot

    Analysis of Heat Transfer Mechanism for Shelf Vacuum Freeze-Drying Equipment

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    Vacuum freeze-drying technology is applicable to the process of high heat-sensitive products. Due to the long drying period and extremely low processing temperature and pressure, the uniform and efficiency of heat transfer fluid temperature in shelf are critical for product quality. Therefore, in this study, the commercial computer fluid dynamics (CFD) software, FLUENT, was utilized for three-dimension numerical simulation of the shelf vacuum freeze-drying process. The influences of different inlet and outlet positions for shelves on the uniformity of the flow rate and temperature were discussed. Moreover, it explored the impacts on the temperature gradient of shelves after heat exchange of different flow rates and low temperature materials. In order to reduce the developing time and optimize the design, the various secondary refrigerants in different plies of shelves were investigated. According to the effect of heat exchange between different flow rates and low temperature layer material shelves on the temperature gradient of shelves surface, the minimum temperature gradient was 20 L/min, and the maximum was 2.5 L/min

    Deep Learning for Spin-Orbit Torque Characterizations with a Projected Vector Field Magnet

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    Spin-orbit torque characterizations on magnetic heterostructures with perpendicular anisotropy are demonstrated on a projected vector field magnet via hysteresis loop shift measurement and harmonic Hall measurement with planar Hall correction. Accurate magnetic field calibration of the vector magnet is realized with the help of deep learning models, which are able to capture the nonlinear behavior between the generated magnetic field and the currents applied to the magnet. The trained models can successfully predict the applied current combinations under the circumstances of magnetic field scans, angle scans, and hysteresis loop shift measurements. The validity of the models is further verified, complemented by the comparison of the spin-orbit torque characterization results obtained from the deep-learning-trained vector magnet system with those obtained from a conventional setup comprised of two separated electromagnets. The damping-like spin-orbit torque (DL-SOT) efficiencies (|ξDL\xi_{DL}|) extracted from the vector magnet and the traditional measurement configuration are consistent, where |ξDL\xi_{DL}| \approx 0.22 for amorphous W and |ξDL\xi_{DL}| \approx 0.02 for α\alpha-W. Our work provides an advanced method to meticulously control a vector magnet and to conveniently perform various spin-orbit torque characterizations

    Lactobacillus plantarum MYL26 induces endotoxin tolerance phenotype in Caco-2 cells

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    Background: Crohn's disease and ulcerative colitis are the major types of chronic inflammatory bowel diseaseoccurring in the colon and small intestine. A growing body of research has proposed that probiotics are able toattenuate the inflammatory symptoms of these diseases in vitro and in vivo. However, the mechanism of probioticactions remains unclear.Results: Our results suggested Lactobacillus plantarum MYL26 inhibited inflammation in Caco-2 cells throughregulation of gene expressions of TOLLIP, SOCS1, SOCS3, and IκBα, rather than SHIP-1 and IRAK-3.Conclusions: We proposed that live/ heat-killed Lactobacillus plantarum MYL26 and bacterial cell wall extracttreatments impaired TLR4-NFκb signal transduction through Tollip, SOCS-1 and SOCS-3 activation, thus inducing LPStolerance. Our findings suggest that either heat-killed probiotics or probiotic cell wall extracts are able to attenuateinflammation through pathways similar to that of live bacteria

    Open lung biopsy in early-stage acute respiratory distress syndrome

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    INTRODUCTION: Acute respiratory distress syndrome (ARDS) has heterogeneous etiologies, rapid progressive change and a high mortality rate. To improve the outcome of ARDS, accurate diagnosis is essential to the application of effective early treatment. The present study investigated the clinical effects and safety of open lung biopsy (OLB) in patients with early-stage ARDS of suspected non-infectious origin. METHODS: We undertook a retrospective study of 41 patients with early-stage ARDS (defined as one week or less after intubation) who underwent OLB in two medical intensive care units of a tertiary care hospital from 1999 to 2005. Data analyzed included baseline characteristics, complication rate, pathological diagnoses, treatment alterations, and hospital survival. RESULTS: The age of patients was 55 ± 17 years (mean ± SD). The average ratio of arterial partial pressure of oxygen (PaO(2)) to fraction of inspired oxygen (FiO(2)) was 116 ± 43 mmHg (mean ± SD) at biopsy. Seventeen patients (41%) were immunocompromised. Postoperative complications occurred in 20% of patients (8/41). All biopsies provided a pathological diagnosis with a diagnostic yield of 100%. Specific pathological diagnoses were made for 44% of patients (18/41). Biopsy findings led to an alteration of treatment modality in 73% of patients (30/41). The treatment alteration rate was higher in patients with nonspecific diagnoses than in patients with specific diagnoses (p = 0.0024). Overall mortality was 50% (21/41) and was not influenced by age, gender, pre-OLB oxygenation, complication rate, pathological results, and alteration of treatment. There was no surgery-related mortality. The survival rate for immunocompromised patients was better than that for immunocompetent patients (71% versus 33%; p = 0.0187) in this study. CONCLUSION: Our retrospective study suggests that OLB was a useful and acceptably safe diagnostic procedure in some selected patients with early-stage ARDS

    High serum levels of procalcitonin and soluble TREM-1 correlated with poor prognosis in pulmonary tuberculosis

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    SummaryObjectivesComparisons of procalcitonin (PCT), C-reactive protein (CRP), and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) would expand our knowledge of which biomarker is the best predictor for outcomes of patients with pulmonary tuberculosis (PTB).MethodsWe prospectively enrolled 243 PTB patients, in whom PCT, CRP, and sTREM-1 measurement were performed to evaluate their prognostic value for 6-month mortality.ResultsSerum PCT, CRP, and sTREM-1 levels on diagnosis of PTB were significantly higher in nonsurvivors (2.22 ± 6.22 vs. 0.13 ± 0.31 ng/mL, P = 0.043; 42.1 ± 59.4 vs. 12.5 ± 29.1 mg/L, P = 0.004; 332 ± 362 vs. 128 ± 98 pg/mL, P = 0.001, respectively) as compared with 6-month survivors. In multivariate Cox regression analysis, PCT ≧0.5 ng/mL (hazard ratio 4.13, 95% CI, 1.99–8.58) and sTREM-1 ≧129 pg/mL (hazard ratio 3.39, 95% CI, 1.52–7.58) remained independent mortality predictors. Serum PCT and sTREM-1 levels above the cutoffs were also associated with the presence of disseminated tuberculosis.ConclusionsAmong PTB patients, higher PCT, CRP, and sTREM-1 levels are observed in nonsurvivors than in 6-month survivors. Serum levels of PCT and sTREM-1 over the cutoffs are independently associated with a poor outcome. In addition, higher PCT and sTREM-1 levels would raise the clinical suspicion of disseminated tuberculosis
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