Occlusion of acute distal brachial, proximal radial and ulnar arteries in a young thrower

SummaryAcute arterial occlusion, a rare condition in throwers, requires early detection and treatment for avoiding further complications. Thus far, no study has mentioned the occurrence of distal brachial, proximal radial, and ulnar artery occlusion in baseball players. An adolescent baseball pitcher presented with acute occlusion of the distal brachial, proximal radial, or ulnar artery. The patient complained of a cold sensation in the hand, wrist, and distal forearm. On physical examination, decreased surface skin temperature, and no radial pulse in the wrist suggested arterial occlusion. Emergency angiography validated the clinical suspicion, and identified the arteries and sites of vascular occlusion. Surgery was performed to alleviate the occlusions, thereby resolving the preoperative complaints and abnormal findings. Furthermore, postoperative magnetic resonance imaging of the shoulder and elbow joint was conducted to determine the causes of arterial occlusion. The patient resumed pitching 4 months postoperatively, and has remained active and symptom free. Magnetic resonance imaging examination revealed no vascular abnormalities or bony or soft tissue in the shoulder or elbow region. With early detection and treatment, a favorable prognosis can be achieved in baseball pitchers with acute upper extremity arterial occlusion so that their pitching career is not jeopardized

Dose pre-hospital laryngeal mask airway use has a survival benefit in non-shockable cardiac arrest?

Background. Whether pre-hospital laryngeal mask airway (LMA) use poses a survival benefit and should be approved as routine airway management in non-shockable cardiac arrest is of major concern. The present study examined the effectiveness of LMA, in comparison to other pre-hospital airway management on individuals who have experienced non-shockable cardiac arrest. Methods. Adult patients who experienced non-shockable cardiac arrest with activation of the emergency medical service (EMS) made up our study cohort in Taoyuan, Taiwan. The data were abstracted from EMS records and cardiac arrest registration protocols. Results. Among the 1912 enrolled patients, most received LMA insertion (72.4%), 108 (5.6%) bag-valve-mask (BVM) ventilation, 376 (19.7%) high-flow oxygen non-rebreather facemask, and only 44 (2.3%) received endotracheal tube intubation (ETI). With regard to survival to discharge, no significant differences in prevalence were evident among the groups: 2.8% of oxygen facial mask, 1.1% of BVM, 2.1% of LMA, and 4.5% of the ETI group survived to discharge (p = 0.314). In comparison to oxygen facial mask use, different types of airway management remained unassociated with survival to discharge after adjusting for variables by logistic regression analysis (BVM: 95% confidence interval [CI], 0.079 – 1.639 [p = 0.186]; LMA: 95% CI, 0.220–2.487 [p = 0.627]; ETI: 95% CI, 0.325–17.820 [p = 0.390]). The results of Hosmer-Lemeshow goodness-of-fit test of logistic regression model revealed good calibration. Conclusions. Pre-hospital LMA use was not associated with additional survival to discharge compared with facial oxygen mask, BVM, or ETI following non-shockable cardiac arrest

Interaction induced ferro-electricity in the rotational states of polar molecules

We show that a ferro-electric quantum phase transition can be driven by the dipolar interaction of polar molecules in the presence a micro-wave field. The obtained ferro-electricity crucially depends on the harmonic confinement potential, and the resulting dipole moment persists even when the external field is turned off adiabatically. The transition is shown to be second order for fermions and for bosons of a smaller permanent dipole moment, but is first order for bosons of a larger moment. Our results suggest the possibility of manipulating the microscopic rotational state of polar molecules by tuning the trap's aspect ratio (and other mesoscopic parameters), even though the later's energy scale is smaller than the former's by six orders of magnitude.Comment: 4 pages and 4 figure

THE EFFECT OF REGULA EXERCISE FOR FUNTIONAL HEALTH OF THE ELDERLY

The purpose of this study was to investigate the performance difference in walking, stair descent and ascent, sit-to-stand, and stand-to-sit, between elderlies who exercise regularly and those who don’t. Twenty elderlies participated in this study (8 males and 12 females). All tests were assessed using a 10-camera Vicon system. The visual3D software was used to analyse data. A positive correlation exists between movement time of stair descent and anterior-posterior balance ability. The negative correlations exist between movement time of stair descent and ascent and balance ability in lateral-medial. A significant difference in balance ability of stair decent exists between those with regular exercise and those without. According to the ACSM principle, regular exercise can indeed reduce the chance of falling in the elderly

The Role of a Confined Space on the Reactivity and Emission Properties of Copper(I) Clusters

Metal clusters have gained a lot of interest for their remarkable photoluminescence and catalytic properties. However, a major drawback of such materials is their poor stability in air and humidity conditions. Herein we describe a versatile method to synthesize luminescent Cu(I) clusters inside the pores of zeolites, using a sublimation technique with the help of high vacuum and high temperature. The porous materials play an essential role as a protecting media against the undesirable and easy oxidation of Cu(I). The obtained clusters show fascinating luminescence properties, and their reactivity can be triggered by insertion in the pores of organic monodentate ligands such as pyridine or triphenylphosphine. The coordinating ligands can lead to the formation of Cu(I) complexes with completely different emission properties. In the case of pyridine, the final compound was characterized and identified as a cubane-like structure. A thermochromism effect is also observed, featuring, for instance, a hypsochromic effect for a phosphine derivative at 77K. The stability of the encapsulated systems in zeolites is rather enthralling: they are stable and emissive even after several months in the air

Multi-color emission with orthogonal input triggers from a diarylethene pyrene-OTHO organogelator cocktail

\ua9 2020 The Royal Society of Chemistry. We report on a pyrene-decorated supramolecular gelator based on an oxotriphenylhexanoate (OTHO) that can switch emission profiles between the solution and gel phase. A cocktail of the gelator and a photochromic diarylethene derivative enables four distinct emissive states to be obtained, which are modulated with light and heat as orthogonal input triggers

A novel regulatory event-based gene set analysis method for exploring global functional changes in heterogeneous genomic data sets

<p>Abstract</p> <p>Background</p> <p>Analyzing gene expression data by assessing the significance of pre-defined gene sets, rather than individual genes, has become a main approach in microarray data analysis and this has promisingly derive new biological interpretations of microarray data. However, the detection power of conventional gene list or gene set-based approaches is limited on highly heterogeneous samples, such as tumors.</p> <p>Results</p> <p>We developed a novel method, the regulatory <b>e</b>vent-based <b>G</b>ene <b>S</b>et <b>A</b>nalysis (eGSA), which considers not only the consistently changed genes but also every gene regulation (event) of each sample to overcome the detection limit. In comparison with conventional methods, eGSA can detect functional changes in heterogeneous samples more precisely and robustly. Furthermore, by utilizing eGSA, we successfully revealed novel functional characteristics and potential mechanisms of very early hepatocellular carcinoma (HCC).</p> <p>Conclusion</p> <p>Our study creates a novel scheme to directly target the major cellular functional changes in heterogeneous samples. All potential regulatory routines of a functional change can be further analyzed by the regulatory event frequency. We also provide a case study on early HCCs and reveal a novel insight at the initial stage of hepatocarcinogenesis. eGSA therefore accelerates and refines the interpretation of heterogeneous genomic data sets in the absence of gene-phenotype correlations.</p