sj-docx-1-dhj-10.1177_20552076231205744 - Supplemental material for Machine learning approaches for predicting sleep arousal response based on heart rate variability, oxygen saturation, and body profiles

Supplemental material, sj-docx-1-dhj-10.1177_20552076231205744 for Machine learning approaches for predicting sleep arousal response based on heart rate variability, oxygen saturation, and body profiles by Chih-Fan Kuo, Cheng-Yu Tsai, Wun-Hao Cheng, Wen-Hua Hs, Arnab Majumdar, Marc Stettler, Kang-Yun Lee, Yi-Chun Kuan, Po-Hao Feng, Chien-Hua Tseng, Kuan-Yuan Chen and Jiunn-Horng Kang, Hsin-Chien Lee, Cheng-Jung Wu, Wen-Te Liu in DIGITAL HEALTH</p

Association of day 4 cumulative fluid balance with mortality in critically ill patients with influenza: A multicenter retrospective cohort study in Taiwan - Fig 4

<p><b>Kaplan-Meier survival curves for positive (gray) and negative (black) cumulative day 1–4 fluid balance in the ARDS (A) and non-ARDS (B) groups.</b> ARDS: Acute Respiratory Distress Syndrome.</p

Cox proportional hazard regression analysis for 30-day mortality.

<p>Cox proportional hazard regression analysis for 30-day mortality.</p

Daily and cumulative fluid status of the 296 patients with influenza by 30-day mortality.

<p>Daily and cumulative fluid status of the 296 patients with influenza by 30-day mortality.</p

Flow chart of patient enrollment.

<p>Flow chart of patient enrollment.</p

Data_Sheet_1_Associations of the distance-saturation product and low-attenuation area percentage in pulmonary computed tomography with acute exacerbation in patients with chronic obstructive pulmonary disease.docx

BackgroundChronic obstructive pulmonary disease (COPD) has high global health concerns, and previous research proposed various indicators to predict mortality, such as the distance-saturation product (DSP), derived from the 6-min walk test (6MWT), and the low-attenuation area percentage (LAA%) in pulmonary computed tomographic images. However, the feasibility of using these indicators to evaluate the stability of COPD still remains to be investigated. Associations of the DSP and LAA% with other COPD-related clinical parameters are also unknown. This study, thus, aimed to explore these associations.MethodsThis retrospective study enrolled 111 patients with COPD from northern Taiwan. Individuals’ data we collected included results of a pulmonary function test (PFT), 6MWT, life quality survey [i.e., the modified Medical Research Council (mMRC) scale and COPD assessment test (CAT)], history of acute exacerbation of COPD (AECOPD), and LAA%. Next, the DSP was derived by the distance walked and the lowest oxygen saturation recorded during the 6MWT. In addition, the DSP and clinical phenotype grouping based on clinically significant outcomes by previous study approaches were employed for further investigation (i.e., DSP of 290 m%, LAA% of 20%, and AECOPD frequency of ≥1). Mean comparisons and linear and logistic regression models were utilized to explore associations among the assessed variables.ResultsThe low-DSP group (ConclusionA lower value of the DSP was related to a greater worsening of symptoms, more-frequent exacerbations, poorer pulmonary function, and more-severe emphysema (higher LAA%). These readily determined parameters, including the DSP and LAA%, can serve as indicators for assessing the COPD clinical course and may can serve as a guide to corresponding treatments.</p