Visual feedback availability during grasping modulates lingual/fusiform cortex.

<p>Axial view of the statistical map shows the direct comparison between visual and proprioceptive feedback conditions within the ANOVA, projected onto a group-averaged structural template. Bar graphs illustrate the mean ± SE of the relative BOLD signal intensity (% change) across the experimental conditions for each of the significant clusters. V <i>–</i> visual; P <i>–</i> proprioceptive; Ling/Fus <i>–</i> lingual and fusiform gyri.</p

Grasping-related areas are modulated by the sensory modality x object distance interaction.

<p>Statistical map shows the Sensory Modality x Object Distance interaction within the ANOVA. Spatially normalized activations are projected onto a single-subject brain template in Talairach space. Bar graphs illustrate the mean ± SE of the relative BOLD signal intensity (% change) across the experimental conditions for each of the significant clusters. Significance for distance effect in each sensory modality conditions was reported for T-test p-value<0.05. dPM <i>–</i> dorsal premotor; pC/IPL <i>–</i> post central cortex/inferior parietal lobule; SPL <i>–</i> superior parietal lobule.</p

Schematic view of the experimental setup.

<p>Illustration of participants and target position (near or far from the hand) in the scanner during the visual (panel above) and proprioceptive (panel below) feedback conditions.</p

Cluster sizes and Talairach coordinates for significant brain regions from the three-way mixed-model group ANOVA with Object Distance as within subjects factor, Sensory Feedback as between subjects factor, Participants as random factor and the BOLD percent signal change as dependent variable.

<p> <i>Note: CM – center of mass; Ling/Fus – lingual and fusiform gyri; SPL – superior parietal lobule; pC/IPL – post central gyrus/inferior parietal lobule; dPMC – dorsal premotor cortex; *p<0.001.</i></p

Results from multiple logistic model for the association with positive lymph node status.

<p><i>InSitu</i> were excluded from the analysis. Significant P-values are indicated in bold, nearly significant P-values are indicated in italics.</p

Socio-demographic and medical features of all patients included.

<p>Socio-demographic and medical features of all patients included.</p

Histogram of frequencies (%) of patients with positive lymph node (N1) status by category of life stress events.

<p>Dark bars depict percentage frequencies of N1 patients who experienced repeated stress (at least one event of the category occurred more than once), light bars depict percentage frequencies of N1 patients who did not experience repeated stress (all events in the category occurred once or never). Asterisks indicate significant P-values derived from Chi-squared test.</p

Frequencies of patients by type of stress life events and lymph-node status.

<p>Significant P-values are indicated in bold.</p