54 research outputs found
Naḥw al-qulūb al-ṣaġīr : La « grammaire des cœurs » de ʿAbd al-Karīm al-Qušayrī
La sacralité que l‘islam reconnaît à la langue arabe a poussé les auteurs mystiques à développer une attention particulière au langage et à ses éléments constitutifs. Si donc la reconnaissance du caractère sacrale du langage a été d‘un coté la base sur laquelle les soufis ont forgé leur lexique mystique, elle est aussi à l‘origine d‘un développement doctrinal, beaucoup moins connu jusqu‘à nos jours, qui repose sur une lecture symbolique des règles de la grammaire arabe et de son lexique. Ce texte d‘Abū al-Qāsim al-Qušayrī représente un des plus anciens essais d‘interprétation mystique de la terminologie grammaticale.الطابع القدسي الذي يضيفه الإسلام على اللغة العربية دفع بالمؤلفين المتصوفين إلى المزيد من الانتباه للغة وعناصرها المكوّنة. فإذا كان الاعتراف بالطابع القدسي للغة أساساً، من جهة، للصوفية، لنحت معجمهم الصوفي، فهي أيضاً في أصول تطوير عقائدي، أقلّ انتشاراً حتى يومنا هذا، وهو قائم على قراءة رمزية لقواعد العربية ومعجمها. نص أبي القاسم القشيري أحد أقدم المحاولات لشرح المفردات الصرفية شرحاً صوفياً.The sacredness that Islam acknowledges to arabic language has brought the mystical authors to pay a special attention to the language and his constituent elements. The recognition of the sacred character of speech represents the base on which Sufis formed their mystical lexicon. Moreover, it has also been at the origin of a doctrinal development, not well know until nowadays, which essays a symbolic lecture of Arabic grammar and its lexicon. This text of Abū al-Qāsim al-Qušayrī represents one of the oldest treatises on mystical interpretation of grammar terminology
Silvers, Laury, A Soaring Minaret. Abu Bakr al-Wasiti and the Rise of Baghdadi Sufism (Albany, 2010)
Après la publication d’un article sur la relation maître-disciple et une recherche sur la pensée doctrinale dans le taṣāwwuf des origines, Laury Silvers (Université de Toronto) publie sa première monographie entièrement consacrée à la figure de Muḥammad b. Mūsā Abū Bakr al-Wāsiṭī (m. ca. 320/923). Ce maître khorassanien, surnommé par les maîtres postérieurs à cause de son langage tranchant « un minaret envolé », a soaring minaret, n’a pas livré d’œuvres écrites. Sa pensée a été recueille par ..
Naḥw al-qulūb al-ṣaġīr: Il «Trattato minore sulla grammatica dei cuori» di ‘Abd al-Karīm al-Qušayrī (376-465/986-1072). Presentazione e traduzione annotata
This text of al-Qušayrī is one of the oldest treatises on mystical interpretation of grammar terminology. The recognition of the sacred character of speech was one of the bases on which Sufis formed their mystical lexicon. At the same time the acknowledgement of the sacred character of Arabic leaded the Sufis to develop a symbolic lecture of Arabic grammar and of its lexicon. This item opens new implications about the relationship between theology and language, with particular attention to the problem of metalanguage
Der Prophet des Islams im Blickwechsel
Die Idee, ein Heft über den Propheten des Islams zu machen, entstand im Laufe des ersten Jahres des von der Agence nationale de la recherche und der Deutschen Forschungsgemeinschaft geförderten deutsch-französischen Projekts »PROPHET – Muhammad im Spiegel seiner Gemeinschaft im frühmodernen und modernen Islam«. Dieses großangelegte Forschungsprogramm, an dem viele Wissenschaftler ganz unterschiedlicher Spezialisierungen (sowohl geografisch gesehen wie im Hinblick auf ihre wissenschaftlichen F..
Don't forget primary progressive aphasia for anti-amyloid drugs: An estimation of eligible patients from the Lausanne Memory Center registry.
The study recently published on the clinical effect of lecanemab in early Alzheimer's disease (AD) only includes patients with amnestic presentation. However, a significant portion of AD patients presents a non-amnestic phenotype of AD, such as primary progressive aphasia (PPA) and could benefit of rather than on lecanemab. Therefore, we conducted a 10-year retrospective study at the Leenaards Memory Center in Lausanne (Switzerland) to identify how many PPA patients would be eligible for lecanemab. Among 54 patients with PPA, we identified 11 (20%) eligible patients. Furthermore, almost half of the 18 patients with logopenic variant would be eligible for lecanemab treatment
Origine et finalité du langage dans le moyen âge islamique
This research, issued from a doctoral seminar at the French Institute of Damascus (IFPO - Institut Français du Proche Orient) organized by the authors and Professor Pierre Lory (IFPO / EPHE - Ecole Pratique des Hautes Etudes), aims at inquiring upon the issues related to language during the Islamic Middle-Ages. The two articles explore two dimensions of language, i.e. two different perspectives of the nature and scope of the language: the first, theological and, the second, mystical. Theology and Sufism, although they appear distant and separated from each other, share the same degree of attention to the phenomenon of human language. The first part of the article is devoted to the Mutakallimūn’s discussion on the origin of language and the theological issues related to it. The discussion about the origin of language in the kalām milieux is analyzed on one side in its diachronic perspective, and via the primary sources comparative analysis, on the other. This approach will show how the two main key concepts of tawqīf and muwāḍa‘a are embedded in a strict theological context. The second part of the article will be devoted to the mystical approach on language. The analysis takes into account the mystical and ṣūfī interpretation of grammar of the Ṣūfī master, ʿAbd al-Karīm al-Qušayrī (d. 465/1072) throughout his grammatical works: an accurate reading of which allows to grasp the mystical interpretation of grammar (naḥw) that goes beyond the mere linguistic dimension of the Arabic language. Moreover, from the analysis of al-Qušayrī’s grammatical works a new interpretation of language inscribed into the relation between man and God will arise. Finally, the two articles undertake a sources’ analysis aiming at reconsidering the role of language (the Arabic language) aside from the Arabic grammatical tradition’s boundaries. Reconsidering the role of language as a core issue in its theological and mystic contexts shows how the phenomenon of language intervenes within man’s relationship vis-à-vis the other and God
Regards croisés sur le prophète de l’Islam
L’idée de présenter un dossier sur le prophète de l’islam est née au cours de la première année du projet franco-allemand ANR-DFG « PROPHET – Muhammad in the Mirror of his community in early modern and modern islam ». Cette vaste enquête, qui a occupé un grand nombre de chercheurs issus de spécialisations très différentes (tant au niveau des aires géographiques que des disciplines) a pour vocation de mettre en relation les spécificités françaises et allemandes de la recherche sur l’islam. Les..
Meningeal Relapse of Nodular Lymphocyte Predominant Hodgkin Lymphoma Transformed to T-Cell/Histiocyte-Rich Large B-Cell Lymphoma: A Case Report.
Central nervous system involvement in Hodgkin lymphoma is extremely rare, especially in nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), which usually carries a favorable prognosis. Here we report a case of a young patient with NLPHL, who developed a progressive and fatal neurological deterioration requiring a very extensive work-up including two biopsies to obtain the diagnosis of T-cell/histiocyte-rich large B-cell lymphoma like transformation. This report, which includes post-mortem analysis, highlights the correlations between clinical, radiological, and biological data but also the difficulties encountered in reaching the correct diagnosis
Encephalopathies Associated With Severe COVID-19 Present Neurovascular Unit Alterations Without Evidence for Strong Neuroinflammation.
Coronavirus disease (COVID-19) has been associated with a large variety of neurologic disorders. However, the mechanisms underlying these neurologic complications remain elusive. In this study, we aimed at determining whether neurologic symptoms were caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) direct infection or by either systemic or local proinflammatory mediators.
In this cross-sectional study, we checked for SARS-CoV-2 RNA by quantitative reverse transcription PCR, SARS-CoV-2-specific antibodies, and 49 cytokines/chemokines/growth factors (by Luminex) in the CSF +/- sera of a cohort of 22 COVID-19 patients with neurologic presentation and 55 neurologic control patients (inflammatory neurologic disorder [IND], noninflammatory neurologic disorder, and MS).
We detected anti-SARS-CoV-2 immunoglobulin G in patients with severe COVID-19 with signs of intrathecal synthesis for some of them. Of the 4 categories of tested patients, the CSF of IND exhibited the highest level of cytokines, chemokines, and growth factors. By contrast, patients with COVID-19 did not present overall upregulation of inflammatory mediators in the CSF. However, patients with severe COVID-19 (intensive care unit patients) exhibited higher concentrations of CCL2, CXCL8, and vascular endothelium growth factor A (VEGF-A) in the CSF than patients with a milder form of COVID-19. In addition, we could show that intrathecal CXCL8 synthesis was linked to an elevated albumin ratio and correlated with the increase of peripheral inflammation (serum hepatocyte growth factor [HGF] and CXCL10).
Our results do not indicate active replication of SARS-CoV-2 in the CSF or signs of massive inflammation in the CSF compartment but highlight a specific impairment of the neurovascular unit linked to intrathecal production of CXCL8
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