A High-Accuracy and Power-Efficient Self-Optimizing Wireless Water Level Monitoring IoT Device for Smart City

In this paper; a novel self-optimizing water level monitoring methodology is proposed for smart city applications. Considering system maintenance; the efficiency of power consumption and accuracy will be important for Internet of Things (IoT) devices and systems. A multi-step measurement mechanism and power self-charging process are proposed in this study for improving the efficiency of a device for water level monitoring applications. The proposed methodology improved accuracy by 0.16–0.39% by moving the sensor to estimate the distance relative to different locations. Additional power is generated by executing a multi-step measurement while the power self-optimizing process used dynamically adjusts the settings to balance the current of charging and discharging. The battery level can efficiently go over 50% in a stable charging simulation. These methodologies were successfully implemented using an embedded control device; an ultrasonic sensor module; a LORA transmission module; and a stepper motor. According to the experimental results; the proposed multi-step methodology has the benefits of high accuracy and efficient power consumption for water level monitoring applications

Comparison of Renal Function and Other Health Outcomes in Vegetarians versus Omnivores in Taiwan

Renal disease is one of the top 10 leading causes of death, and the incidence of end-stage renal disease in Taiwan is the highest in the world. Many dietitians consider the diet of plant origin consumed by vegans to be ‘lighter’ and ‘more healthful’ than the diet of both plant and animal origin consumed by omnivores. Dietary protein has significant effects on renal functions. The study explored the effects of both the diets on renal functions. The study subjects included 102 Buddhist nun vegetarians and an equal number of matched control group (omnivores). A cross-sectional study was performed to investigate the effects of the diet of plant origin and the diet of both plant and animal origin on renal functions. There was no difference in the renal functions between the two groups. However, systolic blood pressure, blood urea nitrogen, serum sodium, glucose, cholesterol levels, and urinary specific gravity were lower in the vegetarian group. Although these results were compatible with general concepts regarding diet of plant origin, after adjusting for age, the duration of intake of this diet had no effect on the renal functions. Based on the findings, it is concluded that the renal functions, in terms of the estimated glomerular filtration rate, were not different between the vegetarians and the omnivores

Robust estimation of bacterial cell count from optical density

Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data

A High-Accuracy and Power-Efficient Self-Optimizing Wireless Water Level Monitoring IoT Device for Smart City

In this paper, a novel self-optimizing water level monitoring methodology is proposed for smart city applications. Considering system maintenance, the efficiency of power consumption and accuracy will be important for Internet of Things (IoT) devices and systems. A multi-step measurement mechanism and power self-charging process are proposed in this study for improving the efficiency of a device for water level monitoring applications. The proposed methodology improved accuracy by 0.16–0.39% by moving the sensor to estimate the distance relative to different locations. Additional power is generated by executing a multi-step measurement while the power self-optimizing process used dynamically adjusts the settings to balance the current of charging and discharging. The battery level can efficiently go over 50% in a stable charging simulation. These methodologies were successfully implemented using an embedded control device, an ultrasonic sensor module, a LORA transmission module, and a stepper motor. According to the experimental results, the proposed multi-step methodology has the benefits of high accuracy and efficient power consumption for water level monitoring applications

Effectiveness and Safety of Immunosuppressants and Biological Therapy for Chronic Spontaneous Urticaria: A Network Meta-Analysis

Chronic spontaneous urticaria (CSU) is the most common phenotype of chronic urticaria. We compared treatment effects and safety profiles of the medications in patients with CSU. We searched PubMed, MEDLINE, and Web of Science for randomized control trials (RCTs), from 1 January 2000 to 31 July 2021, which evaluated omalizumab and immunosuppressants. Network meta-analyses (NMAs) were performed with a frequentist approach. Outcome assessments considered the efficacy (Dermatology Life Quality Index (DLQI) and weekly urticaria activity score (UAS7)) and tolerability profiles with evaluations of study quality, inconsistencies, and heterogeneity. We identified 14 studies which we included in our direct and indirect quantitative analyses. Omalizumab demonstrated better efficacy in DLQI and UAS7 outcomes compared to a placebo, and UAS7 assessments also demonstrated better outcomes compared to cyclosporine. Alongside this, omalizumab demonstrated relatively lower incidences of safety concerns compared to the other immunosuppressants. Cyclosporin was also associated with higher odds of adverse events than other treatment options. Our findings indicate that omalizumab resulted in greater improvements in terms of the DLQI and UAS7 with good tolerability in CSU patients compared to the other immunosuppressants

A Novel Low-Power Synchronous Preamble Data Line Chip Design for Oscillator Control Interface

In this paper, a novel low-power synchronous preamble data line protocol chip design for serial communication is proposed. The serial communication only uses two wires, chip select (CS) and secure digital (SD), to transmit and receive data between two devices. The proposed protocol aims to use a fewer number of wires for the interface, therefore reducing the complexity as well as the area of the chip design. Moreover, it increases the efficiency through a synchronous serial communication-controlled oscillator. The low-power synchronous preamble data line protocol design was successfully verified using a field-programmable gate array (FPGA) as a master device and a real chip as a slave device. The signals are checked through the use of a logic analyzer. The realized low-power synchronous preamble data line protocol chip design has a gate count of only 5.07 K gates, a low power dissipation of 12 mW, and a chip area of 453,260 μm2 using the Taiwan semiconductor manufacturing company (TSMC) 0.18 μm CMOS process. Compared with the three-wire serial peripheral interface (SPI) protocol, the proposed design has the advantages of having a lower cost and a lower power consumption