19,106 research outputs found
Self-consistent analysis of carrier-transport and carrier-capture dynamics in quantum cascade intersubband semiconductor lasers
A methodology for the self-consistent analysis of carrier transport and carrier capture aspects of the dynamics of quantum cascade intersubband semiconductor lasers is described in this paper. The approach is used to analyze two prototype quantum cascade lasers. The self-consistent analysis incorporates the calculation of the electron densities and temperatures in each subband, together with the intersubband relaxation time. In the calculation of the relaxation time, we take into account the electron interaction with polar optical and acoustic phonons, as well as electron degeneracy. In addition, we also calculate the capture time, considering backward processes that play a role in the electron transition from an injection into an active region. The calculations indicate intersubband relaxation times of order 1 ps and capture times of order 100 f
Market Structure, Technology Spillovers, and Persistence in Productivity Differentials
Using data from 11 main manufacturing industries in 17 OECD countries, this paper empirically investigates the determinants of cross-country differences in the persistence of productivity differentials Specifically, we focus on the effects of product market structure and technology diffusion. It is found that the manufacturing industries display a wide range of convergence rates. Consistent with theories, the persistence of productivity differentials is found to be positively correlated with the price-cost margin and the intra-industry trade index - the proxies for market monopolistic behavior. The proxies for tecnology diffusion, however, do not exhibit consistently significant effect. Among the conditioning macro variables, productivity convergence appears to be enhanced by human capital but deterred by government spending.Total factor productivity, convergence, market structure, technology diffusion
Testing for Output Convergence: A Re-Examination
This paper investigates output convergence for the G7 countries using multivariate time series techniques. We consider both the null hypotheses of no convergence and convergence. It is shown that inferences on output convergence depend on which one of the two null hypotheses is considered. Further, the no convergence results reported in previous studies using the time series definition may be attributed to the low power of the test procedures being used. Our results also highlight some potential problems on interpreting results from some typical multivariate unit root and stationarity tests.Output convergence, multivariate test, unit root test, stationarity test
Quantization effects in Viterbi decoding rate 1/n convolutional codes
A Viterbi decoder's performance loss due to quantizing data from the additive white Gaussian noise (AWGN) channel is studied. An optimal quantization scheme and branch metric calculation method are presented. The uniformly quantized channel capacity C(sub u)(q) is used to determine the smallest number of quantization bits q that does not cause a significant loss. The quantizer stepsize which maximizes C(sub u)(q) almost minimizes the decoder bit error rate (BER). However, a slightly larger stepsize is better, like the value that minimizes the Bhattacharyya bound. The range and renormalization of state metrics is analyzed, in particular for K = 15 decoders such as the Big Viterbi Decoder (BVD) for the Galileo mission. These results are required to design reduced hardware complexity Viterbi decoders with a negligible quantization loss
What Do We Know about Recent Exchange Rate Models? In-Sample Fit and Out-of-Sample Performance Evaluated
Previous assessments of nominal exchange rate determination have focused upon a narrow set of models typically of the 1970’s vintage, including monetary and portfolio balance models. In this paper we re-assess the in-sample fit and out-of-sample prediction of a wider set of models that have been proposed in the last decade, namely interest rate parity, productivitybased models, and "behavioral equilibrium exchange rate" models. These models are compared against a benchmark model, the Dornbusch-Frankel sticky price monetary model. First, the parameter estimates of the models are compared against the theoretically predicted values. Second, we conduct an extensive out-of-sample forecasting exercise, using the last eight years of data to determine whether our in-sample conclusions hold up. We examine model performance at various forecast horizons (1 quarter, 4 quarters, 20 quarters) using differing metrics (mean squared error, direction of change), as well as the “consistency” test of Cheung and Chinn (1998). We find that no model fits the data particularly well, nor does any model consistently out-predict a random walk, even at long horizons. There is little correspondence between how well a model conforms to theoretical priors and how well the model performs in a prediction context. However, we do confirm previous findings that out-performance of a random walk is more likely at long horizons.exchange rates, monetary model, productivity, interest rate parity, behavioral equilibrium exchange rate model, forecasting performance
Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis
Background
Tumour regression observed in many conditional mouse models following oncogene inactivation provides the impetus to develop, and a platform to preclinically evaluate, novel therapeutics to inactivate specific oncogenes. Inactivating single oncogenes, such as c-Myc, can reverse even advanced tumours. Intriguingly, transient c-Myc inactivation proved sufficient for sustained osteosarcoma regression; the resulting osteocyte differentiation potentially explaining loss of c-Myc's oncogenic properties. But would this apply to other tumours?
Results
We show that brief inactivation of c-Myc does not sustain tumour regression in two distinct tissue types; tumour cells in pancreatic islets and skin epidermis continue to avoid apoptosis after c-Myc reactivation, by virtue of Bcl-xL over-expression or a favourable microenvironment, respectively. Moreover, tumours progress despite reacquiring a differentiated phenotype and partial loss of vasculature during c-Myc inactivation. Interestingly, reactivating c-Myc in β-cell tumours appears to result not only in further growth of the tumour, but also re-expansion of the accompanying angiogenesis and more pronounced β-cell invasion (adenocarcinoma).
Conclusions
Given that transient c-Myc inactivation could under some circumstances produce sustained tumour regression, the possible application of this potentially less toxic strategy in treating other tumours has been suggested. We show that brief inactivation of c-Myc fails to sustain tumour regression in two distinct models of tumourigenesis: pancreatic islets and skin epidermis. These findings challenge the potential for cancer therapies aimed at transient oncogene inactivation, at least under those circumstances where tumour cell differentiation and alteration of epigenetic context fail to reinstate apoptosis. Together, these results suggest that treatment schedules will need to be informed by knowledge of the molecular basis and environmental context of any given cancer
Fast transform decoding of nonsystematic Reed-Solomon codes
A Reed-Solomon (RS) code is considered to be a special case of a redundant residue polynomial (RRP) code, and a fast transform decoding algorithm to correct both errors and erasures is presented. This decoding scheme is an improvement of the decoding algorithm for the RRP code suggested by Shiozaki and Nishida, and can be realized readily on very large scale integration chips
Comment on "Peierls Gap in Mesoscopic Ring Threated by a Magnetic Flux"
In a recent letter, Yi et al. PRL 78, 3523 (1997), have considered the
stability of a Charge Density Wave in a one-dimensional ring, in the presence
of an Aharonov-Bohm flux. This comment shows that, in one dimension, the
stability of the Charge Density Wave depends on the parity of the number of
electrons in the ring. This effect is similar to the parity effect known for
the persistent current in one-dimensional rings.Comment: Latex, 1 page, 2 figure
Compressed/reconstructed test images for CRAF/Cassini
A set of compressed, then reconstructed, test images submitted to the Comet Rendezvous Asteroid Flyby (CRAF)/Cassini project is presented as part of its evaluation of near lossless high compression algorithms for representing image data. A total of seven test image files were provided by the project. The seven test images were compressed, then reconstructed with high quality (root mean square error of approximately one or two gray levels on an 8 bit gray scale), using discrete cosine transforms or Hadamard transforms and efficient entropy coders. The resulting compression ratios varied from about 2:1 to about 10:1, depending on the activity or randomness in the source image. This was accomplished without any special effort to optimize the quantizer or to introduce special postprocessing to filter the reconstruction errors. A more complete set of measurements, showing the relative performance of the compression algorithms over a wide range of compression ratios and reconstruction errors, shows that additional compression is possible at a small sacrifice in fidelity
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