Computational exploration of the relationship between holistic processing and right hemisphere lateralization in featural and configural recognition tasks

Open URL: http://csjarchive.cogsci.rpi.edu/Proceedings/2011/Holistic processing has long been considered as a property of right hemisphere (RH) processing. Nevertheless, recent studies showed reduced holistic processing and increased RH lateralization in Chinese character recognition expertise, suggesting that these two effects may separate. Through computational modeling, in which we implement a theory of hemispheric asymmetry in perception that posits a low frequency bias in the RH and a high frequency bias in the left hemisphere, we show that when the recognition task relies purely on featural information, holistic processing increases whereas RH lateralization decreases with increasing stimulus similarity; there is a negative correlation between them. In contrast, when the task relies purely on configural information, although RH lateralization negatively correlates with stimulus similarity, holistic processing does not correlate with stimulus similarity; there is a positive correlation between them. This suggests that holistic processing and RH lateralization do not always go together, depending on the task requirements.postprintThe 33rd Annual Meeting of the Cognitive Science Society (CogSci 2011), Boston, MA., 20-23 July 2011. In Proceedings of the 33rd CogSci, 2011, p. 2592-259

Prediction of 3-d surface topography in ultra-precision machining

2000-2001 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

A multi-lamp heliodon for architectural schools

Heliodons have been developed to simulate sunlight direction in relation to a building model. For placing the building model, heliodons can be divided into two categories. In one category, the model is to be tilted, and normally also rotated [1,2,3]. In the other category, the model is to be placed horizontally, and normally also stationary [4,5,6]. The later category of heliodons, with a horizontally placed building model, and with the simulated sunlight moving around it, will certainly help architectural students visualise the change of sunlight direction around a building and the related effect on insolation and shading. Furthermore, in both categories, there are heliodons developed [7,8] to examine nnual nsolation/shading on massing models by putting red, green, blue lamps (i.e. dichromatic lamps) respectively at positions for June, September/ March, December, thus improving the capability of the heliodons. In the pursuit of a heliodon capable of demonstrating solar movement, offering the speed of operation as demanded by architectural schools, and occupying a space generally affordable, and primarily suitable for use to test buildings of the climatic region of South China where Hong Kong is located, a multi-lamp heliodon has been developed. This paper reports on this multi-lamp heliodon, which consists of 69 fixed quartz lamps, and 6 dichromatic lamps. It also has the capability of investigating the building model with dichromatic lamps, without the demand of additional space which is always a concern now in architectural schools.http://www.bse.polyu.edu.hk/researchCentre/Fire_Engineering/summary_of_output/journal/IJAS/V1/p.46-58.pd

Peritoneal implantation of ureter in cadaveric renal transplant

Case reportWe report here a case of complication of peritoneal implantation of ureter in cadaveric renal transplant. The patient presented with anuria and delayed graft function. The diagnosis was suspected upon physical examination and radiological investigation. The complication was managed with reimplantation of the ureter into the bladder and the patient recovered with good graft function. We discuss this case, review the literature on this rare complication, and share our suggestions on how it can be prevented.published_or_final_versio

Cutout of proximal femoral nail antirotation resulting from blocking of the gliding mechanism during fracture collapse

The proximal femoral nail antirotation had been successful in treating unstable trochanteric fractures. Previous studies have shown technical problems such as unsatisfactory fracture reduction, poor insertion technique, and poor blade position leading to complications such as cutout. We present a case of proximal femoral nail antirotation cutout resulting from the blocking of the gliding mechanism during fracture collapse by the lateral cortex. The trochanteric fracture had not healed on presentation and there was significant acetabulum protrusion of the device. Thus, a cemented total hip arthroplasty was required. Copyright © 2011 by Lippincott Williams & Wilkins.postprin

Hepatocyte-specific activation of NF-κB does not aggravate chemical hepatocarcinogenesis in transgenic mice

The NF-κB signalling pathway plays important roles in liver organogenesis and cardnogenesis. Mouse embryos deficient in IKKβ die in mid-gestation, due to excessive apoptosis of hepatoblasts. Although activation of the NF-κB signalling pathway has been demonstrated in human hepatocellular carcinoma, the role of NF-κB is controversial. Here, we have generated transgenic mice in which a constitutively active form of IKKβ was expressed in a hepatocyte-specific manner. Using electrophoretic mobility shift assay, we documented increased NF-κB activities and up-regulated levels of NF-κB downstream target genes, Bcl-xL and STAT5, in the transgenic mouse livers. These results confirmed that the NF-κB pathway was activated in the livers of the transgenic mice. However, there was no significant difference in tumour formation between transgenic and wild-type mice up to an age of 50 weeks. When we treated the transgenic mice with the chemical carcinogen diethylnitrosamine (DEN), we observed no significant differences in the incidence and size of liver tumours formed in these mice with and without DEN treatment at 35 weeks of age, suggesting that the activated NF-κB pathway in the livers of the transgenic mice did not enhance hepatocarcinogenesis. Interestingly, some of the transient transgenic embryos (E12.5) had abnormal excessive accumulation of nucleated red blood cells in their developing livers. In summary, NF-κB activation in hepatocytes did not significantly affect chemical hepatocarcinogenesis. In addition, the TTR/IKKCA transgenic mice may serve as a useful model for studying the role of NF-κB activation in hepatocarcinogenesis as well as inflammatory and metabolic diseases. Copyright © 2008 Pathological Society of Great Britain and Ireland.postprin

Enhanced survival and regeneration of axotomized retinal ganglion cells by a mixture of herbal extracts

The aim of this study is to investigate the effects of Panax quinquefolius L. extract (PQE), Ginkgo biloba extract (GBE), and Hypericum perforatum extract (HPE), in combination or alone, on the survival and regeneration of axotomized retinal ganglion cells (RGCs) in an optic nerve transection model in adult hamsters. Unilateral transection of the optic nerve was performed to evaluate the effects of herbal extracts on the survival of axotomized RGCs. Effects of the herbal extracts on axonal regeneration of axotomized RGCs, on the other hand, were studied by attaching a peripheral nerve graft onto the transected ocular stump to induce regeneration. Operated animals received daily oral administration of vehicle or herbal extracts (PQE, GBE, and HPE), alone or in combination, for 7 and 21 days, respectively, in the survival and regeneration experiments. Surviving and regenerating RGCs were retrogradely labeled with Fluoro-Gold. The eyes were then enucleated and the retinas were flat-mounted for the counting of the labeled RGCs. Treatment with PQE, GBE and HPE alone failed to offer neuroprotection to injured RGCs. However, treatment with Menta-FX, a mixture of PQE, GBE, and HPE, significantly augmented RGC survival 7 days postaxotomy. Treatment with Menta-FX also induced a significant (87%) increase in the number of regenerating RGCs 21 days after optic nerve transection. This study demonstrates that herbs can act as a potential neuroprotective agent for damaged RGCs. It also suggests that the therapeutic value of herbal remedies can be maximized by the use of mixtures of appropriate herbs.published_or_final_versio

Defects recognition of microlens array using gabor filters and supported vector machine

2009-2010 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Pearl hunter : an inspired hyper-heuristic

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