Studying Ransomware Attacks Using Web Search Logs

Cyber attacks are increasingly becoming prevalent and causing significant damage to individuals, businesses and even countries. In particular, ransomware attacks have grown significantly over the last decade. We do the first study on mining insights about ransomware attacks by analyzing query logs from Bing web search engine. We first extract ransomware related queries and then build a machine learning model to identify queries where users are seeking support for ransomware attacks. We show that user search behavior and characteristics are correlated with ransomware attacks. We also analyse trends in the temporal and geographical space and validate our findings against publicly available information. Lastly, we do a case study on 'Nemty', a popular ransomware, to show that it is possible to derive accurate insights about cyber attacks by query log analysis.Comment: To appear in the proceedings of SIGIR 202

Reforming Higher Education in India: In Pursuit of Excellence

Higher education has emerged as one of the most critical factors for the Nation’s economic, political, social and cultural growth and development. Reforming the higher education sector has become an emergent norm across the globe, especially in the developing world. India is one such emerging nation, witnessing a major shift in its ideological, pragmatic and policy directions in the last few years. The higher education sector in India has witnessed unprecedented expansion. However, given the distinctive social-political-economic context and its complexity in India, expansion in higher education is often linked with ensuring equity and access. Whereas in the developed world, expansion is often associated with quality or excellence in higher education i.e. creating world-class universities. Further, excellence in higher education is arguably the most critical component for the survival, sustenance and growth of the sector. To this end, the paper examines the convergence and divergence in policies and practices related to the pursuit of excellence in higher education and its institutions in India vis-à-vis the dominant global reforms in higher education. Erstwhile policies related to quality in higher education and the current draft National Education Policy-2019, provide a reference to the local-distinctive strategies for seeking excellence at the systemic and the institutional level, with an aspiration for global reputation. For instance, National Institutional Ranking Framework, University Grants Commission’s graded autonomy, Institutional restructuring, National Accreditation and Assessment Council and Quacquarelli Symonds- India rating and so on. The paper also sets direction on how Local strategies for global aspirations could unpack a series of issues regarding the reforms in education and delineate in what ways that these emerging global reforms, strategies are effective and appropriate to the local higher education system and its institutions.Singai, C.; Kumaraswamy, TR.; Chandra, A. (2020). Reforming Higher Education in India: In Pursuit of Excellence. En 6th International Conference on Higher Education Advances (HEAd'20). Editorial Universitat Politècnica de València. (30-05-2020):1209-1213. https://doi.org/10.4995/HEAd20.2020.11237OCS1209121330-05-202

Establishing a Benchmark of Fuel Efficiency for Commercial Airline Operations

Fuel efficiency is vital for commercial airlines as fuel is one of the most costly items for airline operations. This study aims to compare fuel efficiencies of selected airlines around the globe and to build a benchmark of fuel efficiency that can be referred to by airlines. By using data on fuel consumption and traffic output collected from various sources including airline annual reports, environmental reports and sustainability reports, this study calculated fuel efficiencies measured by liters of fuel consumed per revenue tonne kilometer (RTK) for the selected airlines in the calendar year 2011 or financial year 2010–2011. Airlines were also compared and ranked by their respective fuel efficiencies. It was found that, depending on whether the passenger equivalent freight mass (PEFM) was 91 kg or 160 kg, the average fuel efficiency of the airlines studied is 0.4 L/RTK or 0.278 L/RTK, respectively. Variances in fuel efficiency among airlines from different regions and airlines of different business models were also found by this study

Nudge: Accelerating Overdue Pull Requests Towards Completion

Pull requests are a key part of the collaborative software development and code review process today. However, pull requests can also slow down the software development process when the reviewer(s) or the author do not actively engage with the pull request. In this work, we design an end-to-end service, Nudge, for accelerating overdue pull requests towards completion by reminding the author or the reviewer(s) to engage with their overdue pull requests. First, we use models based on effort estimation and machine learning to predict the completion time for a given pull request. Second, we use activity detection to reduce false positives. Lastly, we use dependency determination to understand the blocker of the pull request and nudge the appropriate actor(author or reviewer(s)). We also do a correlation analysis to understand the statistical relationship between the pull request completion times and various pull request and developer related attributes. Nudge has been deployed on 147 repositories at Microsoft since 2019. We do a large scale evaluation based on the implicit and explicit feedback we received from sending the Nudge notifications on 8,500 pull requests. We observe significant reduction in completion time, by over 60%, for pull requests which were nudged thus increasing the efficiency of the code review process and accelerating the pull request progression

Anxiety and depression among people living in quarantine centers during COVID-19 pandemic: a mixed method study from western Nepal

Background In response to the COVID-19 pandemic, incoming travelers were quarantined at specific centers in Nepal and major checkpoints in Nepal-India border. Nepal adopted a generic public health approaches to control and quarantine returnee migrants, with little attention towards the quality of quarantine facilities and its aftermath, such as the poor mental health of the returnee migrants. The main objective of this study was to explore the status of anxiety and depression, and factors affecting them among returnee migrants living in institutional quarantine centers of western Nepal. Methods A mixed method approach in this study included a quantitative survey and in-depth interviews (IDIs) among respondents in quarantine centers of Karnali province between 21st April and 15th May 2020. Survey questionnaire utilized Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) tools, which were administered among 441 quarantined returnee migrants. IDIs were conducted among 12 participants which included a mix of six quarantined migrants and healthcare workers each from the quarantine centres. Descriptive and inferential analyses were conducted on quantitative data; and thematic analysis was utilized for qualitative data. Results Mild depression (9.1%; 40/441) and anxiety (16.1%; 71/441) was common among respondents followed by moderate depression and anxiety {depression (3.4%; 15/441), anxiety (4.1%; 18/441)} and severe depression and anxiety {depression (1.1%; 5/441), anxiety (0.7%; 3/441)}. Anxiety and depression were independent of their socio-demographic characteristics. Perceived fear of contracting COVID-19, severity and death were prominent among the respondents. Respondents experienced stigma and discrimination in addition to being at the risk of disease and possible loss of employment and financial responsibilities. In addition, poor (quality and access to) health services, and poor living condition at the quarantine centres adversely affected respondents’ mental health. Conclusion Depression and anxiety were high among quarantined population and warrants more research. Institutional quarantine centers of Karnali province of Nepal were in poor conditions which adversely impacted mental health of the respondents. Poor resource allocation for health, hygiene and living conditions can be counterproductive to the population quarantined

Impelling Factors for Contracting COVID-19 Among Surgical Professionals During the Pandemic: A Multinational Cohort Study.

BACKGROUND Medical workers, including surgical professionals working in coronavirus disease 2019 (COVID-19) treating hospitals, were under enormous stress during the pandemic. This global study investigated factors endowing COVID-19 amongst surgical professionals and students. METHODS This global cross-sectional survey was made live on February 18, 2021 and closed for analysis on March 13, 2021. It was freely shared on social and scientific media platforms and was sent via email groups and circulated through a personal network of authors. Chi-square test for independence, and binary logistic regression analysis were carried out on determining predictors of surgical professionals contracting COVID-19. RESULTS This survey captured the response of 520 surgical professionals from 66 countries. Of the professionals, 92.5% (481/520) reported practising in hospitals managing COVID-19 patients. More than one-fourth (25.6%) of the respondents (133/520) reported suffering from COVID-19 which was more frequent in surgical professionals practising in public sector healthcare institutions (P = 0.001). Thirty-seven percent of those who reported never contracting COVID-19 (139/376) reported being still asked to practice self-isolation and wear a shield without the diagnosis (P = 0.001). Of those who did not contract COVID-19, 75.7% (283/376) were vaccinated (P < 0.001). Surgical professionals undergoing practice in the private sector (odds ratio (OR): 0.33; 95% confidence interval (CI): 0.14 - 0.77; P = 0.011) and receiving two doses of vaccine (OR: 0.55; 95% CI: 0.32 - 0.95; P = 0.031) were identified to enjoy decreased odds of contracting COVID-19. Only 6.9% of those who reported not contracting COVID-19 (26/376) were calculated to have the highest "overall composite level of harm" score (P < 0.001). CONCLUSIONS High prevalence of respondents got COVID-19, which was more frequent in participants working in public sector hospitals. Those who reported contracting COVID-19 were calculated to have the highest level of harm score. Self-isolation or shield, getting two doses of vaccines decreases the odds of contracting COVID-19

Distinct External Signals Trigger Sequential Release of Apical Organelles during Erythrocyte Invasion by Malaria Parasites

The invasion of erythrocytes by Plasmodium merozoites requires specific interactions between host receptors and parasite ligands. Parasite proteins that bind erythrocyte receptors during invasion are localized in apical organelles called micronemes and rhoptries. The regulated secretion of microneme and rhoptry proteins to the merozoite surface to enable receptor binding is a critical step in the invasion process. The sequence of these secretion events and the external signals that trigger release are not known. We have used time-lapse video microscopy to study changes in intracellular calcium levels in Plasmodium falciparum merozoites during erythrocyte invasion. In addition, we have developed flow cytometry based methods to measure relative levels of cytosolic calcium and study surface expression of apical organelle proteins in P. falciparum merozoites in response to different external signals. We demonstrate that exposure of P. falciparum merozoites to low potassium ion concentrations as found in blood plasma leads to a rise in cytosolic calcium levels through a phospholipase C mediated pathway. Rise in cytosolic calcium triggers secretion of microneme proteins such as the 175 kD erythrocyte binding antigen (EBA175) and apical membrane antigen-1 (AMA-1) to the merozoite surface. Subsequently, interaction of EBA175 with glycophorin A (glyA), its receptor on erythrocytes, restores basal cytosolic calcium levels and triggers release of rhoptry proteins. Our results identify for the first time the external signals responsible for the sequential release of microneme and rhoptry proteins during erythrocyte invasion and provide a starting point for the dissection of signal transduction pathways involved in regulated exocytosis of these key apical organelles. Signaling pathway components involved in apical organelle discharge may serve as novel targets for drug development since inhibition of microneme and rhoptry secretion can block invasion and limit blood-stage parasite growth

Plasmodium falciparum Reticulocyte Binding-Like Homologue Protein 2 (PfRH2) Is a Key Adhesive Molecule Involved in Erythrocyte Invasion

Erythrocyte invasion by Plasmodium merozoites is a complex, multistep process that is mediated by a number of parasite ligand-erythrocyte receptor interactions. One such family of parasite ligands includes the P. falciparum reticulocyte binding homologue (PfRH) proteins that are homologous with the P. vivax reticulocyte binding proteins and have been shown to play a role in erythrocyte invasion. There are five functional PfRH proteins of which only PfRH2a/2b have not yet been demonstrated to bind erythrocytes. In this study, we demonstrated that native PfRH2a/2b is processed near the N-terminus yielding fragments of 220 kDa and 80 kDa that exhibit differential erythrocyte binding specificities. The erythrocyte binding specificity of the 220 kDa processed fragment of native PfRH2a/2b was sialic acid-independent, trypsin resistant and chymotrypsin sensitive. This specific binding phenotype is consistent with previous studies that disrupted the PfRH2a/2b genes and demonstrated that PfRH2b is involved in a sialic acid independent, trypsin resistant, chymotrypsin sensitive invasion pathway. Interestingly, we found that the smaller 80 kDa PfRH2a/2b fragment is processed from the larger 220 kDa fragment and binds erythrocytes in a sialic acid dependent, trypsin resistant and chymotrypsin sensitive manner. Thus, the two processed fragments of PfRH2a/2b differed with respect to their dependence on sialic acids for erythrocyte binding. Further, we mapped the erythrocyte binding domain of PfRH2a/2b to a conserved 40 kDa N-terminal region (rPfRH240) in the ectodomain that is common to both PfRH2a and PfRH2b. We demonstrated that recombinant rPfRH240 bound human erythrocytes with the same specificity as the native 220 kDa processed protein. Moreover, antibodies generated against rPfRH240 blocked erythrocyte invasion by P. falciparum through a sialic acid independent pathway. PfRH2a/2b thus plays a key role in erythrocyte invasion and its conserved receptor-binding domain deserves attention as a promising candidate for inclusion in a blood-stage malaria vaccine