73 research outputs found
Evaluation of iminodiacetic acid derivatives of ortho and meta amino hippuric acid analogs as renal function agents
Computational and experimental simulations of the haemodynamics at cuffed arterial bypass graft anastomoses
Investigation of complex equilibria in solutions of p-aminohippuric acid and tin (II) ion in perchlorate medium
The complex equilibrium in tin (II)-p-aminohippuric acid (PAH) solutions in perchlorate medium was investigated. The interaction between Sn (II)-ion and PAH was studied with the purpose to establish whether PAH could form complex with, Sn (II)-ion during the labeling with technetium-99m. HPLC, spectrophotometric and pH-metric methods were used. Dissociation constants of PAH, thermodynamic parameters of PAH dissociation, as well as stability constant of tin (II)-PAH were determined. The values of thermodynamic dissociation constants of PAH were 4.25, 4.19 and 4.15 at 295, 302 and 310 K respectively. The calculated thermodynamic values DeltaGdegrees, DeltaHdegrees and DeltaSdegrees, were -24.01 KJ mol(-1), -12.44 KJ mol(-1) and 39.22 Jmol(-1) K-1 at 295 K respectively. Sn (II)-ion exhibits only a weak interaction with PAH in the pH range 2.0 divided by 3.7, e.g. in the Sn-PAH solution a weak complex with high degree of dissociation was obtained. The treatment of spectral data referring to Sn-PAH solutions indicates the formation of a mononuclear complex [SnPAH](+). Mathematical analysis of experimental data indicated that the best fit of the potentiometric data was achieved by assuming the formation of a mixed hydrolytic complex [Sn(OH)PAH]. The calculated value of the stability constant was: log beta(1,-1.1) = 0.95 +/- 0.11 at 298 K
Investigation of Complex Equilibria in Solutions of p-Aminohippuric Acid and Tin (II) Ion in Perchlorate Medium
An unusual presentation of thoracoacromial artery pseudoaneurysm following shoulder arthroplasty
- …