The study of the endothelial protective properties of the L-norvaline combination with mexidol in the simulation of L-NAME-induced NO deficiency

The endothelium is considered as a target for the prevention and treatment of pathological processes leading to cardiovascular diseases. A combination of L-norvaline at a dose of 10 mg/kg and mexidol at a dose of 60 mg/kg against the background of L-NAME-induced endothelial dysfunction has a pronounced endothelial protective effect. The investigated drugs showed pronounced endothelial protective activity and can be recommended for further pre-clinical studie

A clinical case of non-compact cardiomyopathy after autovenous coronary bypass grafting

The purpose of the study is to study the features of a case of LVNC in a patient with concomitant cardiovascular pathology.Цель исследования – изучение особенностей течения случая некомпактного миокарда у пациента с сопутствующей сердечно-сосудистой патологией

Experience of the student scientific society as a factor of increasing the potential of students at the department of public health and health

The purpose of the study is to description the experience of conducting a student scientific society and organizing an Olympiad at the Department of Public Health and Health.Цель исследования – описание опыта проведения студенческого научного общества и организации олимпиады на кафедре общественного здоровья и здравоохранения ФГБОУ ВО УГМУ Минздрава РФ

Study of Endothelio- and Osteoprotective Effects of Combination of Rosuvastatin with L-Norvaline in Experiment

The experiment was carried out on 120 female white Wistar rats, to study the endothelio- and osteoprotective action of the combination of rosuvastatin with L-norvaline in the model of experimental osteoporosis. It was found that, after ovariectomy in rats, endothelial dysfunction of the vessels of the microcirculatory bed of bone tissue develops, leading to the appearance of osteoporosis, but the combination of the studied drugs prevents the decrease in the level of microcirculation in the bone tissue, thereby preventing the thinning of bone trabeculae and preventing the occurrence of microfractures in them