The Design and Implementation of Mobile Monitoring System of Transmitting Station Based on Android Platform

AbstractIn view of the high speed development of current mobile platform related technology and wireless telecommunication technology, this paper designs and realized a radio and television launching pad mobile monitoring system based on Android platform. The system as expansion of the present scene monitoring system to receive real-time data on transmitters and control their states by wireless network at any time and place, thus further improve the operation efficiency of transmitting station

MReD: A Meta-Review Dataset for Structure-Controllable Text Generation

When directly using existing text generation datasets for controllable generation, we are facing the problem of not having the domain knowledge and thus the aspects that could be controlled are limited. A typical example is when using CNN/Daily Mail dataset for controllable text summarization, there is no guided information on the emphasis of summary sentences. A more useful text generator should leverage both the input text and the control signal to guide the generation, which can only be built with a deep understanding of the domain knowledge. Motivated by this vision, our paper introduces a new text generation dataset, named MReD. Our new dataset consists of 7,089 meta-reviews and all its 45k meta-review sentences are manually annotated with one of the 9 carefully defined categories, including abstract, strength, decision, etc. We present experimental results on start-of-the-art summarization models, and propose methods for structure-controlled generation with both extractive and abstractive models using our annotated data. By exploring various settings and analyzing the model behavior with respect to the control signal, we demonstrate the challenges of our proposed task and the values of our dataset MReD. Meanwhile, MReD also allows us to have a better understanding of the meta-review domain.Comment: 15 pages, 5 figures, accepted at ACL 202

A new method for pore structure quantification and pore network extraction from SEM images

C.W. thanks China Scholarship Council’s financial support for his Ph.D. study. The authors thank Anasuria Operating Company Limited (AOC) for making available the core plug samples. We thank the two reviewers for their insight comments and constructive suggestions toward improving our manuscript. Finally, we thank John Still (University of Aberdeen Centre for Electron Microscopy, Analysis and Characterisation (ACEMAC)) for invaluable assistance in the acquisition of SEM images.Peer reviewedPostprin

Application of online-offline integrated medical care management in patients with gestational diabetes

Objectives: To investigate efficacy of online-offline integrated medical care management in patients with gestational diabetes. Material and methods: A total of 140 patients with gestational diabetes were randomly divided into two groups: integrated management (IM) group (n = 70) and control group (n = 70). Patients in the control group were treated with routine nursing intervention, and the patients in the IM group were treated with integrated care (offline medical and nursing management combined with WeChat online management). The fasting plasma glucose (FPG), 2h postprandial plasma glucose (2hPG), Self-rating Anxiety Scale (SAS) score, Self-rating Depression Scale (SDS) score, Diabetes Care Profile (DPC) score, 36-item Short-Form (SF-36) score, and poor pregnancy outcomes were compared between the two groups. Results: After intervention, the FPG, 2hPG, SAS score, SDS score, DPC score and SF-36 score were improved in both groups. All indicators in the IM group were better than the control group (p < 0.05). The incidence of premature delivery, polyhydramnios, neonatal respiratory distress, intrauterine distress, and postpartum hemorrhage in the IM group were lower than those in the control group (p < 0.05). Conclusions: The online-offline integrated medical care management effectively improved the blood glucose level, mental state, self-management behavior, quality of life and pregnancy outcomes of patients with gestational diabetes

Geographic Distribution and Genetic Diversity of Rice Stripe Mosaic Virus in Southern China

Rice stripe mosaic virus (RSMV) transmitted by the leafhopper Recilia dorsalis is a tentative new species in the genus Cytorhabdovirus identified recently in South China. To explore its geographic distribution and genetic diversity, field investigation and viral whole-genome sequencing were conducted in this study. The results indicated that RSMV was present in the rice samples collected across southern China. Twelve representative samples from different geographical regions were selected for viral whole-genome sequencing and the viral genome variation was analyzed in combination with a previously reported RSMV isolate. Identity analysis showed that the genome sequences of 13 RSMV isolates were highly conserved with nucleotide identities over 99.4%. There was a strong negative selection pressure during the evolution of RSMV with more transitions (72.08%) than transversions (27.92%) found between the RSMV isolates. Among the seven genes encoded by RSMV, the P gene was the most variable, followed by N, M, L, and G; the P3 and P6 amino acid sequences were not found to be mutated and no mutations were found in the non-coding region. A phylogenetic tree based on the RSMV whole-genome nucleotide sequences revealed that all RSMV isolates clustered in two groups based on geographical origin. Notably, the L proteins of the Guangxi and Hainan isolates had five and one specific amino acid sites, respectively, suggesting that the L gene has undergone environmental adaptive variation during the dispersal of RSMV

Molecular characterization of cathepsin B from Clonorchis sinensis excretory/secretory products and assessment of its potential for serodiagnosis of clonorchiasis

<p>Abstract</p> <p>Background</p> <p>Cathepsin cysteine proteases play multiple roles in the life cycle of parasites such as food uptake, immune invasion and pathogenesis, making them valuable targets for diagnostic assays, vaccines and drugs. The purpose of this study was to identify a cathepsin B of <it>Clonorchis sinensis </it>(<it>Cs</it>CB) and to investigate its diagnostic value for human helminthiases.</p> <p>Results</p> <p>The predicted amino acid sequence of the cathepsin B of <it>C. sinensis </it>shared 63%, 52%, 50% identity with that of <it>Schistosoma japonicum</it>, <it>Homo sapiens </it>and <it>Fasciola hepatica</it>, respectively. Sequence encoding proenzyme of <it>Cs</it>CB was overexpressed in <it>Escherichia coli</it>. Reverse transcription PCR experiments revealed that <it>Cs</it>CB transcribed in both adult worm and metacercaria of <it>C. sinensis</it>. <it>Cs</it>CB was identified as a <it>C. sinensis </it>excretory/secretory product by immunoblot assay, which was consistent with immunohistochemical localization showing that <it>Cs</it>CB was especially expressed in the intestine of <it>C. sinensis </it>adults. Both ELISA and western blotting analysis showed recombinant <it>Cs</it>CB could react with human sera from clonorchiasis and other helminthiases.</p> <p>Conclusions</p> <p>Our findings revealed that secreted CsCB may play an important role in the biology of C. sinensis and could be a diagnostic candidate for helminthiases.</p

IKKα negatively regulates ASC-dependent inflammasome activation.

The inflammasomes are multiprotein complexes that activate caspase-1 in response to infections and stress, resulting in the secretion of pro-inflammatory cytokines. Here we report that IκB kinase α (IKKα) is a critical negative regulator of apoptosis-associated specklike protein containing a C-terminal caspase-activation-andrecruitment (CARD) domain (ASC)-dependent inflammasomes. IKKα controls the inflammasome at the level of the adaptor ASC, which interacts with IKKα in the nucleus of resting macrophages in an IKKα kinase-dependent manner. Loss of IKKα kinase activity results in inflammasome hyperactivation. Mechanistically, the downstream nuclear effector IKK-related kinase (IKKi) facilitates translocation of ASC from the nucleus to the perinuclear area during inflammasome activation. ASC remains under the control of IKKα in the perinuclear area following translocation of the ASC/IKKα complex. Signal 2 of NLRP3 activation leads to inhibition of IKKα kinase activity through the recruitment of PP2A, allowing ASC to participate in NLRP3 inflammasome assembly. Taken together, these findings reveal a IKKi-IKKα-ASC axis that serves as a common regulatory mechanism for ASC-dependent inflammasomes